2024
Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications
OLIVER-URRUTIA, Carolina; Mariano CASAS-LUNA; Zuzana SUMBALOVÁ KOLEDOVÁ; Karel SLAMECKA; Tomas ZIKMUND et al.Základní údaje
Originální název
Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications
Autoři
OLIVER-URRUTIA, Carolina; Mariano CASAS-LUNA; Zuzana SUMBALOVÁ KOLEDOVÁ; Karel SLAMECKA; Tomas ZIKMUND; Jozef KAISER; Ladislav CELKO a Edgar B. MONTUFAR
Vydání
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T, AMSTERDAM, ELSEVIER, 2024, 2238-7854
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
20601 Medical engineering
Stát vydavatele
Nizozemské království
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 6.600
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/24:00137424
Organizační jednotka
Lékařská fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
Titanium; Metallic foam; Scaffold; Direct foaming; Robocasting; Osteoblast
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 25. 10. 2024 10:44, Mgr. Tereza Miškechová
Anotace
V originále
Titanium (Ti) foams offer a promising alternative for bone reconstruction and repair due to their high porosity and lower stiffness compared to solid metals, which improves in vivo osseointegration by reducing the stress shielding effect and allowing bone ingrowth. In this work, customized Ti foams were successfully fabricated for the first time at room temperature using a direct foaming method. Ti powder suspension with a water-soluble surfactant and environmentally friendly thickener was foamed by mechanical stirring. Then, 3D-printed moulds were utilized to achieve near-net shape foams, which were subsequently consolidated by sintering, thus avoiding the need for complex processing of molten Ti. The resulting Ti foams exhibited a cancellous-like open-cell structure, high porosity (> 80%), and a five times higher effective surface area than a 3D Ti mesh with a primitive cubic-based cell fabricated by additive manufacturing. In addition, the Ti foams exhibited similar mechanical properties to cancellous bone and facilitated the adhesion, proliferation, and maturation of human osteoblasts in vitro.
Návaznosti
| 90251, velká výzkumná infrastruktura |
|