Vitamin D supplementation in cancer prevention and the
management of cancer therapy

J 2024

Vitamin D supplementation in cancer prevention and the management of cancer therapy

KLENA, Ladislav; Kristina GALVANKOVA; Adela PENESOVA a Oľga KRIŽANOVÁ

Základní údaje

Originální název

Vitamin D supplementation in cancer prevention and the management of cancer therapy

Autoři

KLENA, Ladislav; Kristina GALVANKOVA; Adela PENESOVA a Oľga KRIŽANOVÁ

Vydání

Neoplasma, Bratislava, Aepress, 2024, 0028-2685

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30204 Oncology

Stát vydavatele

Slovensko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.200

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/24:00137798

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

vitamin D; cancer; vitamin D receptor; obesity

Štítky

14110515, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 28. 11. 2024 08:41, Mgr. Tereza Miškechová

Anotace

V originále

Vitamin D is an important steroid hormone that exerts immunomodulatory actions, controls calcium and phosphate homeostasis, and significantly affects human health. Vitamin D deficiency is a global health problem, affecting approximately 60% of adults worldwide, and has been implicated in a range of different types of diseases, e.g., cancer. Vitamin D is involved in the regulation of cell proliferation, differentiation, energetic metabolism, and different types of cell death (e.g., apoptosis, autophagy, etc.). In physiological conditions, it is also able to modulate immune responses, angiogenesis, etc., which belongs to fundamental cancer-related processes. Vitamin D deficiency has been associated with an increased risk of some types of cancer, e.g., colorectal, breast, ovarian, prostate, pancreatic, etc. The role of vitamin D in cancer prevention, carcinogenesis, and cancer treatment is still under investigation and depends on the type of cancer. This review summarizes the role of vitamin D in all three above-mentioned aspects and discusses the mechanism of action and potential possibilities in cancer treatment.

Citovat

KLENA, Ladislav; Kristina GALVANKOVA; Adela PENESOVA a Oľga KRIŽANOVÁ. Vitamin D supplementation in cancer prevention and the management of cancer therapy. Neoplasma. Bratislava: Aepress, 2024, roč. 71, č. 4, s. 307-318. ISSN 0028-2685. Dostupné z: https://doi.org/10.4149/neo_2024_240531N240.

@article{2455438,
   author = {Klena, Ladislav and Galvankova, Kristina and Penesova, Adela and Križanová, Oľga},
   article_location = {Bratislava},
   article_number = {4},
   doi = {https://doi.org/10.4149/neo_2024_240531N240},
   keywords = {vitamin D; cancer; vitamin D receptor; obesity},
   language = {eng},
   issn = {0028-2685},
   journal = {Neoplasma},
   title = {Vitamin D supplementation in cancer prevention and the management of cancer therapy},
   url = {https://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=8394&category_id=196&option=com_virtuemart},
   volume = {71},
   year = {2024}
}

TY  - JOUR
ID  - 2455438
AU  - Klena, Ladislav - Galvankova, Kristina - Penesova, Adela - Križanová, Oľga
PY  - 2024
TI  - Vitamin D supplementation in cancer prevention and the management of cancer therapy
JF  - Neoplasma
VL  - 71
IS  - 4
SP  - 307-318
EP  - 307-318
PB  - Aepress
SN  - 00282685
KW  - vitamin D
KW  - cancer
KW  - vitamin D receptor
KW  - obesity
UR  - https://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=8394&category_id=196&option=com_virtuemart
N2  - Vitamin D is an important steroid hormone that exerts immunomodulatory actions, controls calcium and phosphate homeostasis, and significantly affects human health. Vitamin D deficiency is a global health problem, affecting approximately 60% of adults worldwide, and has been implicated in a range of different types of diseases, e.g., cancer. Vitamin D is involved in the regulation of cell proliferation, differentiation, energetic metabolism, and different types of cell death (e.g., apoptosis, autophagy, etc.). In physiological conditions, it is also able to modulate immune responses, angiogenesis, etc., which belongs to fundamental cancer-related processes. Vitamin D deficiency has been associated with an increased risk of some types of cancer, e.g., colorectal, breast, ovarian, prostate, pancreatic, etc. The role of vitamin D in cancer prevention, carcinogenesis, and cancer treatment is still under investigation and depends on the type of cancer. This review summarizes the role of vitamin D in all three above-mentioned aspects and discusses the mechanism of action and potential possibilities in cancer treatment.
ER  -

KLENA, Ladislav; Kristina GALVANKOVA; Adela PENESOVA a Oľga KRIŽANOVÁ. Vitamin D supplementation in cancer prevention and the management of cancer therapy. \textit{Neoplasma}. Bratislava: Aepress, 2024, roč.~71, č.~4, s.~307-318. ISSN~0028-2685. Dostupné z: https://doi.org/10.4149/neo\_{}2024\_{}240531N240.

Přehled o publikaci