Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial
BOSSERDT, Maria; Lina M SERNA-HIGUITA; Gudrun FEUCHTNER; Bela MERKELY; Klaus F KOFOED et. al.
Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial
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BOSSERDT, Maria; Lina M SERNA-HIGUITA; Gudrun FEUCHTNER; Bela MERKELY; Klaus F KOFOED; Theodora BENEDEK; Patrick DONNELLY; Jose RODRIGUEZ-PALOMARES; Andrejs ERGLIS; Cyril STECHOVSKY; Gintare SAKALYTE; Nada Cemerlic ADIC; Matthias GUTBERLET; Jonathan D DODD; Ignacio DIEZ; Gershan DAVIS; Elke ZIMMERMANN; Cezary KEPKA; Radosav VIDAKOVIC; Marco FRANCONE; Malgorzata ILNICKA-SUCKIEL; Fabian PLANK; Juhani KNUUTI; Rita FARIA; Stephen SCHROEDER; Colin BERRY; Luca SABA; Balazs RUZSICS; Nina RIECKMANN; Christine KUBIAK; Kristian Schultz HANSEN; Jacqueline MUELLER-NORDHORN; Balint SZILVESZTER; Per E SIGVARDSEN; Imre BENEDEK; Clare ORR; Filipa Xavier VALENTE; Ligita ZVAIGZNE; Vojtech SUCHANEK; Antanas JANKAUSKAS; Filip ADIC; Michael WOINKE; Mark HENSEY; Inigo LECUMBERRI; Erica THWAITE; Michael LAULE; Mariusz KRUK; Aleksandar N NESKOVIC; Massimo MANCONE; Donata KUSMIERZ; Mikko PIETILAE; Vasco Gama RIBEIRO; Tanja DROSCH; Christian DELLES; Maurizio PORCU; Michael FISHER; Melinda BOUSSOUSSOU; Charlotte KRAGELUND; Rosca AURELIAN; Stephanie KELLY; del Blanco Bruno GARCIA; Ainhoa RUBIO; Pal MAUROVICH-HORVAT; Jens D HOVE; Ioana RODEAN; Susan REGAN; Hug CUELLAR-CALABRIA; Levente MOLNAR; Linnea LARSEN; Roxana HODAS; Adriane E NAPP; Robert HAASE; Sarah FEGER; Mahmoud MOHAMED; Konrad NEUMANN; Henryk DREGER; Matthias RIEF; Viktoria WIESKE; Melanie ESTRELLA; Peter MARTUS; Harold C SOX a Marc DEWEY
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JAMA Cardiology, Chicago, American Medical Association, 2024, 2380-6583
Importance The effectiveness and safety of computed tomography (CT) and invasive coronary angiography (ICA) in different age groups is unknown. Objective To determine the association of age with outcomes of CT and ICA in patients with stable chest pain. Design, Setting, and Participants The assessor-blinded Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial was conducted between October 2015 and April 2019 in 26 European centers. Patients referred for ICA with stable chest pain and an intermediate probability of obstructive coronary artery disease were analyzed in an intention-to-treat analysis. Data were analyzed from July 2022 to January 2023. Interventions Patients were randomly assigned to a CT-first strategy or a direct-to-ICA strategy.
BOSSERDT, Maria; Lina M SERNA-HIGUITA; Gudrun FEUCHTNER; Bela MERKELY; Klaus F KOFOED; Theodora BENEDEK; Patrick DONNELLY; Jose RODRIGUEZ-PALOMARES; Andrejs ERGLIS; Cyril STECHOVSKY; Gintare SAKALYTE; Nada Cemerlic ADIC; Matthias GUTBERLET; Jonathan D DODD; Ignacio DIEZ; Gershan DAVIS; Elke ZIMMERMANN; Cezary KEPKA; Radosav VIDAKOVIC; Marco FRANCONE; Malgorzata ILNICKA-SUCKIEL; Fabian PLANK; Juhani KNUUTI; Rita FARIA; Stephen SCHROEDER; Colin BERRY; Luca SABA; Balazs RUZSICS; Nina RIECKMANN; Christine KUBIAK; Kristian Schultz HANSEN; Jacqueline MUELLER-NORDHORN; Balint SZILVESZTER; Per E SIGVARDSEN; Imre BENEDEK; Clare ORR; Filipa Xavier VALENTE; Ligita ZVAIGZNE; Vojtech SUCHANEK; Antanas JANKAUSKAS; Filip ADIC; Michael WOINKE; Mark HENSEY; Inigo LECUMBERRI; Erica THWAITE; Michael LAULE; Mariusz KRUK; Aleksandar N NESKOVIC; Massimo MANCONE; Donata KUSMIERZ; Mikko PIETILAE; Vasco Gama RIBEIRO; Tanja DROSCH; Christian DELLES; Maurizio PORCU; Michael FISHER; Melinda BOUSSOUSSOU; Charlotte KRAGELUND; Rosca AURELIAN; Stephanie KELLY; del Blanco Bruno GARCIA; Ainhoa RUBIO; Pal MAUROVICH-HORVAT; Jens D HOVE; Ioana RODEAN; Susan REGAN; Hug CUELLAR-CALABRIA; Levente MOLNAR; Linnea LARSEN; Roxana HODAS; Adriane E NAPP; Robert HAASE; Sarah FEGER; Mahmoud MOHAMED; Konrad NEUMANN; Henryk DREGER; Matthias RIEF; Viktoria WIESKE; Melanie ESTRELLA; Peter MARTUS; Harold C SOX a Marc DEWEY. Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial. JAMA Cardiology. Chicago: American Medical Association, 2024, roč. 9, č. 4, s. 346-356. ISSN 2380-6583. Dostupné z: https://dx.doi.org/10.1001/jamacardio.2024.0001.
@article{2466319, author = {Bosserdt, Maria and SernaandHiguita, Lina M and Feuchtner, Gudrun and Merkely, Bela and Kofoed, Klaus F and Benedek, Theodora and Donnelly, Patrick and RodriguezandPalomares, Jose and Erglis, Andrejs and Stechovsky, Cyril and Sakalyte, Gintare and Adic, Nada Cemerlic and Gutberlet, Matthias and Dodd, Jonathan D and Diez, Ignacio and Davis, Gershan and Zimmermann, Elke and Kepka, Cezary and Vidakovic, Radosav and Francone, Marco and IlnickaandSuckiel, Malgorzata and Plank, Fabian and Knuuti, Juhani and Faria, Rita and Schroeder, Stephen and Berry, Colin and Saba, Luca and Ruzsics, Balazs and Rieckmann, Nina and Kubiak, Christine and Hansen, Kristian Schultz and MuellerandNordhorn, Jacqueline and Szilveszter, Balint and Sigvardsen, Per E and Benedek, Imre and Orr, Clare and Valente, Filipa Xavier and Zvaigzne, Ligita and Suchanek, Vojtech and Jankauskas, Antanas and Adic, Filip and Woinke, Michael and Hensey, Mark and Lecumberri, Inigo and Thwaite, Erica and Laule, Michael and Kruk, Mariusz and Neskovic, Aleksandar N and Mancone, Massimo and Kusmierz, Donata and Pietilae, Mikko and Ribeiro, Vasco Gama and Drosch, Tanja and Delles, Christian and Porcu, Maurizio and Fisher, Michael and Boussoussou, Melinda and Kragelund, Charlotte and Aurelian, Rosca and Kelly, Stephanie and Garcia, del Blanco Bruno and Rubio, Ainhoa and MaurovichandHorvat, Pal and Hove, Jens D and Rodean, Ioana and Regan, Susan and CuellarandCalabria, Hug and Molnar, Levente and Larsen, Linnea and Hodas, Roxana and Napp, Adriane E and Haase, Robert and Feger, Sarah and Mohamed, Mahmoud and Neumann, Konrad and Dreger, Henryk and Rief, Matthias and Wieske, Viktoria and Estrella, Melanie and Martus, Peter and Sox, Harold C and Dewey, Marc}, article_location = {Chicago}, article_number = {4}, doi = {http://dx.doi.org/10.1001/jamacardio.2024.0001}, keywords = {DISCHARGE TRIAL; computed tomography; invasive coronary angiography; MACE}, language = {eng}, issn = {2380-6583}, journal = {JAMA Cardiology}, title = {Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial}, url = {https://jamanetwork.com/journals/jamacardiology/article-abstract/2815696}, volume = {9}, year = {2024} }
TY - JOUR ID - 2466319 AU - Bosserdt, Maria - Serna-Higuita, Lina M - Feuchtner, Gudrun - Merkely, Bela - Kofoed, Klaus F - Benedek, Theodora - Donnelly, Patrick - Rodriguez-Palomares, Jose - Erglis, Andrejs - Stechovsky, Cyril - Sakalyte, Gintare - Adic, Nada Cemerlic - Gutberlet, Matthias - Dodd, Jonathan D - Diez, Ignacio - Davis, Gershan - Zimmermann, Elke - Kepka, Cezary - Vidakovic, Radosav - Francone, Marco - Ilnicka-Suckiel, Malgorzata - Plank, Fabian - Knuuti, Juhani - Faria, Rita - Schroeder, Stephen - Berry, Colin - Saba, Luca - Ruzsics, Balazs - Rieckmann, Nina - Kubiak, Christine - Hansen, Kristian Schultz - Mueller-Nordhorn, Jacqueline - Szilveszter, Balint - Sigvardsen, Per E - Benedek, Imre - Orr, Clare - Valente, Filipa Xavier - Zvaigzne, Ligita - Suchanek, Vojtech - Jankauskas, Antanas - Adic, Filip - Woinke, Michael - Hensey, Mark - Lecumberri, Inigo - Thwaite, Erica - Laule, Michael - Kruk, Mariusz - Neskovic, Aleksandar N - Mancone, Massimo - Kusmierz, Donata - Pietilae, Mikko - Ribeiro, Vasco Gama - Drosch, Tanja - Delles, Christian - Porcu, Maurizio - Fisher, Michael - Boussoussou, Melinda - Kragelund, Charlotte - Aurelian, Rosca - Kelly, Stephanie - Garcia, del Blanco Bruno - Rubio, Ainhoa - Maurovich-Horvat, Pal - Hove, Jens D - Rodean, Ioana - Regan, Susan - Cuellar-Calabria, Hug - Molnar, Levente - Larsen, Linnea - Hodas, Roxana - Napp, Adriane E - Haase, Robert - Feger, Sarah - Mohamed, Mahmoud - Neumann, Konrad - Dreger, Henryk - Rief, Matthias - Wieske, Viktoria - Estrella, Melanie - Martus, Peter - Sox, Harold C - Dewey, Marc PY - 2024 TI - Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial JF - JAMA Cardiology VL - 9 IS - 4 SP - 346-356 EP - 346-356 PB - American Medical Association SN - 23806583 KW - DISCHARGE TRIAL KW - computed tomography KW - invasive coronary angiography KW - MACE UR - https://jamanetwork.com/journals/jamacardiology/article-abstract/2815696 N2 - Importance The effectiveness and safety of computed tomography (CT) and invasive coronary angiography (ICA) in different age groups is unknown. Objective To determine the association of age with outcomes of CT and ICA in patients with stable chest pain. Design, Setting, and Participants The assessor-blinded Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial was conducted between October 2015 and April 2019 in 26 European centers. Patients referred for ICA with stable chest pain and an intermediate probability of obstructive coronary artery disease were analyzed in an intention-to-treat analysis. Data were analyzed from July 2022 to January 2023. Interventions Patients were randomly assigned to a CT-first strategy or a direct-to-ICA strategy. ER -
BOSSERDT, Maria; Lina M SERNA-HIGUITA; Gudrun FEUCHTNER; Bela MERKELY; Klaus F KOFOED; Theodora BENEDEK; Patrick DONNELLY; Jose RODRIGUEZ-PALOMARES; Andrejs ERGLIS; Cyril STECHOVSKY; Gintare SAKALYTE; Nada Cemerlic ADIC; Matthias GUTBERLET; Jonathan D DODD; Ignacio DIEZ; Gershan DAVIS; Elke ZIMMERMANN; Cezary KEPKA; Radosav VIDAKOVIC; Marco FRANCONE; Malgorzata ILNICKA-SUCKIEL; Fabian PLANK; Juhani KNUUTI; Rita FARIA; Stephen SCHROEDER; Colin BERRY; Luca SABA; Balazs RUZSICS; Nina RIECKMANN; Christine KUBIAK; Kristian Schultz HANSEN; Jacqueline MUELLER-NORDHORN; Balint SZILVESZTER; Per E SIGVARDSEN; Imre BENEDEK; Clare ORR; Filipa Xavier VALENTE; Ligita ZVAIGZNE; Vojtech SUCHANEK; Antanas JANKAUSKAS; Filip ADIC; Michael WOINKE; Mark HENSEY; Inigo LECUMBERRI; Erica THWAITE; Michael LAULE; Mariusz KRUK; Aleksandar N NESKOVIC; Massimo MANCONE; Donata KUSMIERZ; Mikko PIETILAE; Vasco Gama RIBEIRO; Tanja DROSCH; Christian DELLES; Maurizio PORCU; Michael FISHER; Melinda BOUSSOUSSOU; Charlotte KRAGELUND; Rosca AURELIAN; Stephanie KELLY; del Blanco Bruno GARCIA; Ainhoa RUBIO; Pal MAUROVICH-HORVAT; Jens D HOVE; Ioana RODEAN; Susan REGAN; Hug CUELLAR-CALABRIA; Levente MOLNAR; Linnea LARSEN; Roxana HODAS; Adriane E NAPP; Robert HAASE; Sarah FEGER; Mahmoud MOHAMED; Konrad NEUMANN; Henryk DREGER; Matthias RIEF; Viktoria WIESKE; Melanie ESTRELLA; Peter MARTUS; Harold C SOX a Marc DEWEY. Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial. \textit{JAMA Cardiology}. Chicago: American Medical Association, 2024, roč.~9, č.~4, s.~346-356. ISSN~2380-6583. Dostupné z: https://dx.doi.org/10.1001/jamacardio.2024.0001.