Amide conjugates of the jasmonate precursor
cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis
during plant stress responses

J 2025

Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses

ŠIROKÁ, Jitka; Anita AMENT; Václav MIK; Tomáš POSPÍŠIL; Michaela KRALOVÁ et. al.

Základní údaje

Originální název

Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses

Autoři

Vydání

Plant Physiology, Oxford University Press, 2025, 0032-0889

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10611 Plant sciences, botany

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.900 v roce 2024

Organizační jednotka

Přírodovědecká fakulta

DOI

https://doi.org/10.1093/plphys/kiae636

UT WoS

001379179400001

EID Scopus

2-s2.0-85214319629

Klíčová slova anglicky

Arabidopsis thaliana; jasmonates; cis-OPDA; OPDA amino acid conjugates

Štítky

143160, CF PLANT, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 3. 2025 15:51, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Jasmonates are a family of oxylipin phytohormones regulating plant development and growth and mediating "defense versus growth" responses. The upstream JA biosynthetic precursor cis-(+)-12-oxo-phytodienoic acid (cis-OPDA) acts independently of CORONATIVE INSENSITIVE 1-mediated JA signaling in several stress-induced and developmental processes. However, its perception and metabolism are only partially understood. An isoleucine analog of the biologically active JA-Ile, OPDA-Ile, was detected years ago in wounded leaves of flowering plants, opening up the possibility that conjugation of cis-OPDA to amino acids might be a relevant mechanism for cis-OPDA regulation. Here, we extended the analysis of amino acid conjugates of cis-OPDA and identified naturally occurring OPDA-Val, OPDA-Phe, OPDA-Ala, OPDA-Glu, and OPDA-Asp accumulating in response to biotic and abiotic stress in Arabidopsis (Arabidopsis thaliana). The OPDA amino acid conjugates displayed cis-OPDA-related plant responses in a JA-Ile-dependent manner. We also showed that the synthesis and hydrolysis of cis-OPDA amino acid conjugates are mediated by members of the amidosynthetase GRETCHEN HAGEN 3 and the amidohydrolase INDOLE-3-ACETYL-LEUCINE RESISTANT 1/ILR1-like families. Thus, OPDA amino acid conjugates function in the catabolism or temporary storage of cis-OPDA in stress responses instead of acting as chemical signals per se.

Citovat

ŠIROKÁ, Jitka; Anita AMENT; Václav MIK; Tomáš POSPÍŠIL; Michaela KRALOVÁ; Chao ZHANG; Markéta PERNISOVÁ; Michal KARADY; Vladimira NOŽKOVÁ; Yuho NISHIZATO; Takuya KAJI; Rina SAITO; Mohamed HTITICH; Kristýna FLOKOVÁ; Claus WASTERNACK; Miroslav STRNAD; Minoru UEDA; Ondřej NOVÁK a Federica BRUNONI. Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses. Plant Physiology. Oxford University Press, 2025, roč. 197, č. 1, s. 1-17. ISSN 0032-0889. Dostupné z: https://doi.org/10.1093/plphys/kiae636.

@article{2472339,
   author = {Široká, Jitka and Ament, Anita and Mik, Václav and Pospíšil, Tomáš and Kralová, Michaela and Zhang, Chao and Pernisová, Markéta and Karady, Michal and Nožková, Vladimira and Nishizato, Yuho and Kaji, Takuya and Saito, Rina and Htitich, Mohamed and Floková, Kristýna and Wasternack, Claus and Strnad, Miroslav and Ueda, Minoru and Novák, Ondřej and Brunoni, Federica},
   article_number = {1},
   doi = {https://doi.org/10.1093/plphys/kiae636},
   keywords = {Arabidopsis thaliana; jasmonates; cis-OPDA; OPDA amino acid conjugates},
   language = {eng},
   issn = {0032-0889},
   journal = {Plant Physiology},
   title = {Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses},
   url = {https://academic.oup.com/plphys/article/197/1/kiae636/7912146},
   volume = {197},
   year = {2025}
}

TY  - JOUR
ID  - 2472339
AU  - Široká, Jitka - Ament, Anita - Mik, Václav - Pospíšil, Tomáš - Kralová, Michaela - Zhang, Chao - Pernisová, Markéta - Karady, Michal - Nožková, Vladimira - Nishizato, Yuho - Kaji, Takuya - Saito, Rina - Htitich, Mohamed - Floková, Kristýna - Wasternack, Claus - Strnad, Miroslav - Ueda, Minoru - Novák, Ondřej - Brunoni, Federica
PY  - 2025
TI  - Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses
JF  - Plant Physiology
VL  - 197
IS  - 1
SP  - 1-17
EP  - 1-17
PB  - Oxford University Press
SN  - 00320889
KW  - Arabidopsis thaliana
KW  - jasmonates
KW  - cis-OPDA
KW  - OPDA amino acid conjugates
UR  - https://academic.oup.com/plphys/article/197/1/kiae636/7912146
N2  - Jasmonates are a family of oxylipin phytohormones regulating plant development and growth and mediating "defense versus growth" responses. The upstream JA biosynthetic precursor cis-(+)-12-oxo-phytodienoic acid (cis-OPDA) acts independently of CORONATIVE INSENSITIVE 1-mediated JA signaling in several stress-induced and developmental processes. However, its perception and metabolism are only partially understood. An isoleucine analog of the biologically active JA-Ile, OPDA-Ile, was detected years ago in wounded leaves of flowering plants, opening up the possibility that conjugation of cis-OPDA to amino acids might be a relevant mechanism for cis-OPDA regulation. Here, we extended the analysis of amino acid conjugates of cis-OPDA and identified naturally occurring OPDA-Val, OPDA-Phe, OPDA-Ala, OPDA-Glu, and OPDA-Asp accumulating in response to biotic and abiotic stress in Arabidopsis (Arabidopsis thaliana). The OPDA amino acid conjugates displayed cis-OPDA-related plant responses in a JA-Ile-dependent manner. We also showed that the synthesis and hydrolysis of cis-OPDA amino acid conjugates are mediated by members of the amidosynthetase GRETCHEN HAGEN 3 and the amidohydrolase INDOLE-3-ACETYL-LEUCINE RESISTANT 1/ILR1-like families. Thus, OPDA amino acid conjugates function in the catabolism or temporary storage of cis-OPDA in stress responses instead of acting as chemical signals per se.
ER  -

ŠIROKÁ, Jitka; Anita AMENT; Václav MIK; Tomáš POSPÍŠIL; Michaela KRALOVÁ; Chao ZHANG; Markéta PERNISOVÁ; Michal KARADY; Vladimira NOŽKOVÁ; Yuho NISHIZATO; Takuya KAJI; Rina SAITO; Mohamed HTITICH; Kristýna FLOKOVÁ; Claus WASTERNACK; Miroslav STRNAD; Minoru UEDA; Ondřej NOVÁK a Federica BRUNONI. Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses. \textit{Plant Physiology}. Oxford University Press, 2025, roč.~197, č.~1, s.~1-17. ISSN~0032-0889. Dostupné z: https://doi.org/10.1093/plphys/kiae636.

Přehled o publikaci