Attenuated total reflection Fourier transform infrared
spectroscopy (ATR-FTIR) analysis of human nails: Implications
for age determination in forensics

J 2025

Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics

MITU, Bilkis; Václav TROJAN; Radovan HŘIB a Lenka HALÁMKOVÁ

Základní údaje

Originální název

Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics

Autoři

MITU, Bilkis; Václav TROJAN; Radovan HŘIB a Lenka HALÁMKOVÁ

Vydání

Journal of Forensic Sciences, Hoboken, Wiley, 2025, 0022-1198

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30100 3.1 Basic medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.800 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14160/25:00140795

Organizační jednotka

Farmaceutická fakulta

Klíčová slova anglicky

age; ATR FT-IR; chemometrics; nails; PLS-DA; PLS-R

Štítky

rivok, ÚPL

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 3. 2026 13:15, Mgr. Irena Doubková

Anotace

V originále

A person's age estimation from biological evidence is a crucial aspect of forensic investigations, aiding in victim identification and criminal profiling. In this study, we present a novel approach of utilizing Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) spectroscopy to predict the age of donors based on nail samples. A diverse dataset comprising nails from donors spanning different age groups was analyzed using ATR FT-IR, with subsequent multivariate analysis techniques used for age prediction. The developed partial least squares regression (PLS-R) model demonstrated promising accuracy in age estimation, with a root mean square error of prediction (RMSEP) equal to 11.1 during external validation. Additionally, a partial least squares discriminant analysis (PLS-DA) classification model achieved high accuracy of 88% in classifying donors into younger and older age groups during external validation. This proof-of-concept study highlights the potential of ATR FT-IR spectroscopy as a non-destructive and efficient tool for age estimation in forensic investigations, offering a new approach to forensic analysis with practical implications.

Citovat

MITU, Bilkis; Václav TROJAN; Radovan HŘIB a Lenka HALÁMKOVÁ. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics. Journal of Forensic Sciences. Hoboken: Wiley, 2025, roč. 70, č. 1, s. 150-160. ISSN 0022-1198. Dostupné z: https://doi.org/10.1111/1556-4029.15641.

@article{2483013,
   author = {Mitu, Bilkis and Trojan, Václav and Hřib, Radovan and Halámková, Lenka},
   article_location = {Hoboken},
   article_number = {1},
   doi = {https://doi.org/10.1111/1556-4029.15641},
   keywords = {age; ATR FT-IR; chemometrics; nails; PLS-DA; PLS-R},
   language = {eng},
   issn = {0022-1198},
   journal = {Journal of Forensic Sciences},
   title = {Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics},
   url = {https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15641},
   volume = {70},
   year = {2025}
}

TY  - JOUR
ID  - 2483013
AU  - Mitu, Bilkis - Trojan, Václav - Hřib, Radovan - Halámková, Lenka
PY  - 2025
TI  - Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics
JF  - Journal of Forensic Sciences
VL  - 70
IS  - 1
SP  - 150-160
EP  - 150-160
PB  - Wiley
SN  - 00221198
KW  - age
KW  - ATR FT-IR
KW  - chemometrics
KW  - nails
KW  - PLS-DA
KW  - PLS-R
UR  - https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15641
N2  - A person's age estimation from biological evidence is a crucial aspect of forensic investigations, aiding in victim identification and criminal profiling. In this study, we present a novel approach of utilizing Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) spectroscopy to predict the age of donors based on nail samples. A diverse dataset comprising nails from donors spanning different age groups was analyzed using ATR FT-IR, with subsequent multivariate analysis techniques used for age prediction. The developed partial least squares regression (PLS-R) model demonstrated promising accuracy in age estimation, with a root mean square error of prediction (RMSEP) equal to 11.1 during external validation. Additionally, a partial least squares discriminant analysis (PLS-DA) classification model achieved high accuracy of 88% in classifying donors into younger and older age groups during external validation. This proof-of-concept study highlights the potential of ATR FT-IR spectroscopy as a non-destructive and efficient tool for age estimation in forensic investigations, offering a new approach to forensic analysis with practical implications.
ER  -

MITU, Bilkis; Václav TROJAN; Radovan HŘIB a Lenka HALÁMKOVÁ. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics. \textit{Journal of Forensic Sciences}. Hoboken: Wiley, 2025, roč.~70, č.~1, s.~150-160. ISSN~0022-1198. Dostupné z: https://doi.org/10.1111/1556-4029.15641.

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