Stimuli-responsive thin film composites of conducting polymers
and cellulose nanocrystals for tissue engineering

J 2024

Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering

KORÁBKOVÁ, Eva; Zhanna BOEVA; Katarzyna Anna RADASZKIEWICZ; Kateřina SKOPALOVÁ; Věra KAŠPÁRKOVÁ et al.

Základní údaje

Originální název

Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering

Autoři

Vydání

International Journal of Biological Macromolecules, Elsevier, 2024, 0141-8130

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10404 Polymer science

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 8.500

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/24:00139764

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Cellulose nanocrystals; Polypyrrole; Poly(3.4-ethylenedioxythiophene); Human induced pluripotent stem cells

Štítky

14314010, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 3. 2025 13:49, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Thin composite films comprising two primary representatives of conducting polymers, poly(3, 4-ethylenedioxythiophene) (PEDOT) and polypyrrole (PPy), with eco-friendly cellulose nanocrystals (CNC) were prepared through electrochemical polymerization. The combination of CNC and PEDOT (or PPy) results in the formation of films with highly different surface topography and thickness. Intriguingly, different surface conductivity of PEDOT and PPy was revealed by atomic force microscopy albeit that the electrochemical properties were rather similar. The biological properties of the composites in contact with prospective human induced pluripotent stem cells (hiPSC) and cardiomyocytes derived from hiPSC demonstrated good cytocompatibility of both composites and their potential in engineering of electro-sensitive tissues. The as-prepared conducting, eco-friendly and cytocompatible composites are thus promising candidates for biomedical applications where stimuli-responsivity is a crucial cell-instructive property.

Návaznosti

GA23-07425S, projekt VaV

Název: Anisotropní a elektricky vodivé biomateriály

Investor: Grantová agentura ČR, Elektricky vodivé biomateriály

Citovat

KORÁBKOVÁ, Eva; Zhanna BOEVA; Katarzyna Anna RADASZKIEWICZ; Kateřina SKOPALOVÁ; Věra KAŠPÁRKOVÁ; Wenyang XU; Xiaoju WANG; Jiří PACHERNÍK; Antonín MINAŘÍK; Tom LINDFORS a Petr HUMPOLÍČEK. Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering. International Journal of Biological Macromolecules. Elsevier, 2024, roč. 265, April, s. 1-10. ISSN 0141-8130. Dostupné z: https://doi.org/10.1016/j.ijbiomac.2024.131036.

@article{2486398,
   author = {Korábková, Eva and Boeva, Zhanna and Radaszkiewicz, Katarzyna Anna and Skopalová, Kateřina and Kašpárková, Věra and Xu, Wenyang and Wang, Xiaoju and Pacherník, Jiří and Minařík, Antonín and Lindfors, Tom and Humpolíček, Petr},
   article_number = {April},
   doi = {https://doi.org/10.1016/j.ijbiomac.2024.131036},
   keywords = {Cellulose nanocrystals; Polypyrrole; Poly(3.4-ethylenedioxythiophene); Human induced pluripotent stem cells},
   language = {eng},
   issn = {0141-8130},
   journal = {International Journal of Biological Macromolecules},
   title = {Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering},
   url = {https://doi.org/10.1016/j.ijbiomac.2024.131036},
   volume = {265},
   year = {2024}
}

TY  - JOUR
ID  - 2486398
AU  - Korábková, Eva - Boeva, Zhanna - Radaszkiewicz, Katarzyna Anna - Skopalová, Kateřina - Kašpárková, Věra - Xu, Wenyang - Wang, Xiaoju - Pacherník, Jiří - Minařík, Antonín - Lindfors, Tom - Humpolíček, Petr
PY  - 2024
TI  - Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering
JF  - International Journal of Biological Macromolecules
VL  - 265
IS  - April
SP  - 1-10
EP  - 1-10
PB  - Elsevier
SN  - 01418130
KW  - Cellulose nanocrystals
KW  - Polypyrrole
KW  - Poly(3.4-ethylenedioxythiophene)
KW  - Human induced pluripotent stem cells
UR  - https://doi.org/10.1016/j.ijbiomac.2024.131036
N2  - Thin composite films comprising two primary representatives of conducting polymers, poly(3, 4-ethylenedioxythiophene) (PEDOT) and polypyrrole (PPy), with eco-friendly cellulose nanocrystals (CNC) were prepared through electrochemical polymerization. The combination of CNC and PEDOT (or PPy) results in the formation of films with highly different surface topography and thickness. Intriguingly, different surface conductivity of PEDOT and PPy was revealed by atomic force microscopy albeit that the electrochemical properties were rather similar. The biological properties of the composites in contact with prospective human induced pluripotent stem cells (hiPSC) and cardiomyocytes derived from hiPSC demonstrated good cytocompatibility of both composites and their potential in engineering of electro-sensitive tissues. The as-prepared conducting, eco-friendly and cytocompatible composites are thus promising candidates for biomedical applications where stimuli-responsivity is a crucial cell-instructive property.
ER  -

KORÁBKOVÁ, Eva; Zhanna BOEVA; Katarzyna Anna RADASZKIEWICZ; Kateřina SKOPALOVÁ; Věra KAŠPÁRKOVÁ; Wenyang XU; Xiaoju WANG; Jiří PACHERNÍK; Antonín MINAŘÍK; Tom LINDFORS a Petr HUMPOLÍČEK. Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering. \textit{International Journal of Biological Macromolecules}. Elsevier, 2024, roč.~265, April, s.~1-10. ISSN~0141-8130. Dostupné z: https://doi.org/10.1016/j.ijbiomac.2024.131036.

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