Towards a comprehensive methodology for ecotoxicological
assessment: Prioritizing plant protection products for mixture
testing in edge-of-field surface waterbodies

J 2024

Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies

ABRANTES, Nelson; Joana Luísa PEREIRA; Ana-Belén Muñiz GONZÁLEZ; Isabel CAMPOS; Irene NAVARRO et al.

Základní údaje

Originální název

Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies

Autoři

Vydání

Science of The Total Environment, Elsevier B.V. 2024, 0048-9697

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 8.000

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/24:00140908

Organizační jednotka

Přírodovědecká fakulta

DOI

https://doi.org/10.1016/j.scitotenv.2024.177322

EID Scopus

2-s2.0-85208110311

Klíčová slova anglicky

Pesticides; Risk quotient; Mixtures; Risk assessment; Freshwater

Štítky

143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 6. 2025 09:46, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Pesticide applications in agriculture result in complex mixtures of Plant Protection Products (PPPs) in the environment. The ecotoxicological effects of these mixtures can occur at concentrations considered safe for individual chemicals, indicating potential risks underestimated by current regulatory assessments focused on individual active ingredients. To address this challenge, our study introduces a methodology for identifying priority PPPs for formulating mixtures, enabling further ecotoxicological testing in water and sediment compartments of edge-of-field surface water bodies, targeting pelagic and benthic organisms. This methodology was primarily based on the actual quantification of PPPs present in these compartments from selected case study sites (CSSs) in Europe and Argentina (11 and 4 for water and sediments, respectively). A conceptual framework was developed that discriminates and selects concerning PPPs based on their individual risk quotient and frequency of occurrence in each CSS, drawing upon two EU regulatory risk assessment approaches, i.e., the general approach under REACH for any environmental contaminant of concern – the European Chemicals Agency (ECHA) approach; and that specifically focusing on PPPs – the European Food Safety Authority (EFSA) approach. Irrespective of whether the focus is on water or sediments, the study revealed disparities in PPP rankings depending on the approach used to identify PPPs of concern, with the ECHA approach being more conservative than the EFSA approach. Despite this, the EFSA approach follows a more standardized assessment factor definition strategy, potentially allowing avoidance of risk overestimation, as well as resulting in a more balanced representation of different PPP classes for subsequent mixtures testing. Overall, the methodological development reported herein, along with the inconsistencies found when comparing different regulatory approaches to assess the risk of environmental contaminants, highlight the need for further discussion on the most appropriate directions towards the standardization of the regulatory risk assessment of PPP mixtures.

Návaznosti

862568, interní kód MU

Název: Sustainable Plant Protection Transition: A Global Health Approach (Akronym: SPRINT)

Investor: Evropská unie, Sustainable Plant Protection Transition: A Global Health Approach, Food security, sustainable agriculture and forestry, marine and maritime and inland water research (Societal Challenges)

Citovat

ABRANTES, Nelson; Joana Luísa PEREIRA; Ana-Belén Muñiz GONZÁLEZ; Isabel CAMPOS; Irene NAVARRO; Adrián DE LA TORRE; María Ángeles MARTÍNEZ; Rima OSMAN; Chrow KHURSHID; Paula HARKES; Esperanza Huerta LWANGA; Francisco ALCON; Josefa CONTRERAS; Isabelle BALDI; Mathilde BUREAU; Abdallah ALAOUI; Florian CHRIST; Daniele MANDRIOLI; Daria SGARGI; Igor PASKOVIĆ; Igor PASKOVIĆ; Marija Polić PASKOVIĆ; Matjaž GLAVAN; Jakub HOFMAN; Trine NORGAARD; Virginia APARICIO a Vera SILVA. Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies. Science of The Total Environment. Elsevier B.V., 2024, roč. 956, December, s. 1-13. ISSN 0048-9697. Dostupné z: https://doi.org/10.1016/j.scitotenv.2024.177322.

@article{2488137,
   author = {Abrantes, Nelson and Pereira, Joana Luísa and González, AnaandBelén Muñiz and Campos, Isabel and Navarro, Irene and de la Torre, Adrián and Martínez, María Ángeles and Osman, Rima and Khurshid, Chrow and Harkes, Paula and Lwanga, Esperanza Huerta and Alcon, Francisco and Contreras, Josefa and Baldi, Isabelle and Bureau, Mathilde and Alaoui, Abdallah and Christ, Florian and Mandrioli, Daniele and Sgargi, Daria and Pasković, Igor and Pasković, Igor and Pasković, Marija Polić and Glavan, Matjaž and Hofman, Jakub and Norgaard, Trine and Aparicio, Virginia and Silva, Vera},
   article_number = {December},
   doi = {https://doi.org/10.1016/j.scitotenv.2024.177322},
   keywords = {Pesticides; Risk quotient; Mixtures; Risk assessment; Freshwater},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of The Total Environment},
   title = {Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies},
   url = {https://doi.org/10.1016/j.scitotenv.2024.177322},
   volume = {956},
   year = {2024}
}

TY  - JOUR
ID  - 2488137
AU  - Abrantes, Nelson - Pereira, Joana Luísa - González, Ana-Belén Muñiz - Campos, Isabel - Navarro, Irene - de la Torre, Adrián - Martínez, María Ángeles - Osman, Rima - Khurshid, Chrow - Harkes, Paula - Lwanga, Esperanza Huerta - Alcon, Francisco - Contreras, Josefa - Baldi, Isabelle - Bureau, Mathilde - Alaoui, Abdallah - Christ, Florian - Mandrioli, Daniele - Sgargi, Daria - Pasković, Igor - Pasković, Igor - Pasković, Marija Polić - Glavan, Matjaž - Hofman, Jakub - Norgaard, Trine - Aparicio, Virginia - Silva, Vera
PY  - 2024
TI  - Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies
JF  - Science of The Total Environment
VL  - 956
IS  - December
SP  - 1-13
EP  - 1-13
PB  - Elsevier B.V.
SN  - 00489697
KW  - Pesticides
KW  - Risk quotient
KW  - Mixtures
KW  - Risk assessment
KW  - Freshwater
UR  - https://doi.org/10.1016/j.scitotenv.2024.177322
N2  - Pesticide applications in agriculture result in complex mixtures of Plant Protection Products (PPPs) in the environment. The ecotoxicological effects of these mixtures can occur at concentrations considered safe for individual chemicals, indicating potential risks underestimated by current regulatory assessments focused on individual active ingredients. To address this challenge, our study introduces a methodology for identifying priority PPPs for formulating mixtures, enabling further ecotoxicological testing in water and sediment compartments of edge-of-field surface water bodies, targeting pelagic and benthic organisms. This methodology was primarily based on the actual quantification of PPPs present in these compartments from selected case study sites (CSSs) in Europe and Argentina (11 and 4 for water and sediments, respectively). A conceptual framework was developed that discriminates and selects concerning PPPs based on their individual risk quotient and frequency of occurrence in each CSS, drawing upon two EU regulatory risk assessment approaches, i.e., the general approach under REACH for any environmental contaminant of concern – the European Chemicals Agency (ECHA) approach; and that specifically focusing on PPPs – the European Food Safety Authority (EFSA) approach. Irrespective of whether the focus is on water or sediments, the study revealed disparities in PPP rankings depending on the approach used to identify PPPs of concern, with the ECHA approach being more conservative than the EFSA approach. Despite this, the EFSA approach follows a more standardized assessment factor definition strategy, potentially allowing avoidance of risk overestimation, as well as resulting in a more balanced representation of different PPP classes for subsequent mixtures testing. Overall, the methodological development reported herein, along with the inconsistencies found when comparing different regulatory approaches to assess the risk of environmental contaminants, highlight the need for further discussion on the most appropriate directions towards the standardization of the regulatory risk assessment of PPP mixtures.
ER  -

ABRANTES, Nelson; Joana Luísa PEREIRA; Ana-Belén Muñiz GONZÁLEZ; Isabel CAMPOS; Irene NAVARRO; Adrián DE LA TORRE; María Ángeles MARTÍNEZ; Rima OSMAN; Chrow KHURSHID; Paula HARKES; Esperanza Huerta LWANGA; Francisco ALCON; Josefa CONTRERAS; Isabelle BALDI; Mathilde BUREAU; Abdallah ALAOUI; Florian CHRIST; Daniele MANDRIOLI; Daria SGARGI; Igor PASKOVI$\backslash$'C; Igor PASKOVI$\backslash$'C; Marija Poli$\backslash$'c PASKOVI$\backslash$'C; Matjaž GLAVAN; Jakub HOFMAN; Trine NORGAARD; Virginia APARICIO a Vera SILVA. Towards a comprehensive methodology for ecotoxicological assessment: Prioritizing plant protection products for mixture testing in edge-of-field surface waterbodies. \textit{Science of The Total Environment}. Elsevier B.V., 2024, roč.~956, December, s.~1-13. ISSN~0048-9697. Dostupné z: https://doi.org/10.1016/j.scitotenv.2024.177322.

Přehled o publikaci