Comprehensive characterization of European house dust
contaminants: Concentrations and profiles, geographical
variability, and implications for chemical regulation and
health risk

J 2024

Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk

HAGLUND, Peter; Nikiforos A. ALYGIZAKIS; Adrian COVACI; Lisa Emily MELYMUK; Pernilla Bohlin NIZZETTO et al.

Základní údaje

Originální název

Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk

Autoři

Vydání

Science of The Total Environment, Elsevier B.V. 2024, 0048-9697

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 8.000

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/24:00140909

Organizační jednotka

Přírodovědecká fakulta

DOI

https://doi.org/10.1016/j.scitotenv.2024.177639

EID Scopus

2-s2.0-85210753396

Klíčová slova anglicky

Geographical trends; House dust; Human exposome; Mass spectrometry; Organic contaminant profiling; Risk assessment

Štítky

143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 30. 7. 2025 12:33, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

This study investigated the concentration profiles and geographical variability of contaminants in house dust across Europe. A collaborative trial (CT) was organized by the NORMAN network using pooled dust and advanced chromatographic and mass spectrometric techniques combined with suspect screening and non-target screening (NTS). Over 1200 anthropogenic compounds were tentatively identified. Additionally, seventy-five individual samples were subjected to target analysis and NTS. The median concentrations of most contaminants varied <3-fold across Europe, and the contaminant profile of European dust was similar to that of North American dust, which was investigated in a previous CT. This similarity may be attributed to the use of similar consumer articles and building materials throughout the developed world. Multivariate data analysis revealed geographical trends in contaminant distribution, with north-south gradients across Europe. Geographical trends were more frequently found for compounds with rapid release (pharmaceuticals, personal care products, fragrances, pesticides, biocides) and smoke-related compounds. The concentrations of chlorinated paraffins, polycyclic aromatic hydrocarbons (PAHs), perfluorinated alkyl substances and stimulants generally increased from north to south, whereas the biocides levels decreased from north to south. Despite widespread presence of in-use contaminants in dusts, some of the highest risks come from compounds that have been restricted for decades or more. These include di(2-ethylhexyl) phthalate (DEHP), polychlorinated biphenyl (PCB) 118 and polybrominated diphenyl ethers 47, 99, and 153. DEHP remains the most abundant contaminant in European house dust, while the other compounds are classified as persistent organic pollutants (POPs). Moreover, there is a striking lack of reliable toxicity data, particularly for emerging compounds. For instance, although acceptable daily intakes (ADIs) were examined for 202 compounds, only 46 had consensus-based ADI values. The results highlight the need for proactive measures to prevent hazardous chemicals from entering the market and for careful selection of substitute chemicals, when such are needed, to avoid regrettable substitutions.

Návaznosti

GA22-32743S, projekt VaV

Název: Propojení složení chemických látek a mikrobiomu v domácím prachu s environmentálními parametry

Investor: Grantová agentura ČR, Propojení složení chemických látek a mikrobiomu v domácím prachu s environmentálními parametry

LM2023069, projekt VaV

Název: Výzkumná infrastruktura RECETOX

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

857560, interní kód MU
(Kód CEP: EF17_043/0009632)

Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)

Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation

Citovat

HAGLUND, Peter; Nikiforos A. ALYGIZAKIS; Adrian COVACI; Lisa Emily MELYMUK; Pernilla Bohlin NIZZETTO; Pawel ROSTKOWSKI; Alexandre ALBINET; Sylvana ALIRAI; Dagny AURICH; Stefan BIEBER; Ana BALLESTEROS-GÓMEZ; Amanda A. BRENNAN; Hélène BUDZINSKI; Gabriela CASTRO; Fatima DEN OUDEN; Marie-Hélène DÉVIER; Valeria DULIO; Yong-Lai FENG; Marta GABRIEL; Christine GALLAMPOIS a Xianyu WANG. Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk. Science of The Total Environment. Elsevier B.V., 2024, roč. 957, December, s. 1-20. ISSN 0048-9697. Dostupné z: https://doi.org/10.1016/j.scitotenv.2024.177639.

@article{2488156,
   author = {Haglund, Peter and Alygizakis, Nikiforos A. and Covaci, Adrian and Melymuk, Lisa Emily and Nizzetto, Pernilla Bohlin and Rostkowski, Pawel and Albinet, Alexandre and Alirai, Sylvana and Aurich, Dagny and Bieber, Stefan and BallesterosandGómez, Ana and Brennan, Amanda A. and Budzinski, Hélène and Castro, Gabriela and den Ouden, Fatima and Dévier, MarieandHélène and Dulio, Valeria and Feng, YongandLai and Gabriel, Marta and Gallampois, Christine and Wang, Xianyu},
   article_number = {December},
   doi = {https://doi.org/10.1016/j.scitotenv.2024.177639},
   keywords = {Geographical trends; House dust; Human exposome; Mass spectrometry; Organic contaminant profiling; Risk assessment},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of The Total Environment},
   note = {Nedoplňovat EF17_043/0009632.},
   title = {Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk},
   url = {https://doi.org/10.1016/j.scitotenv.2024.177639},
   volume = {957},
   year = {2024}
}

TY  - JOUR
ID  - 2488156
AU  - Haglund, Peter - Alygizakis, Nikiforos A. - Covaci, Adrian - Melymuk, Lisa Emily - Nizzetto, Pernilla Bohlin - Rostkowski, Pawel - Albinet, Alexandre - Alirai, Sylvana - Aurich, Dagny - Bieber, Stefan - Ballesteros-Gómez, Ana - Brennan, Amanda A. - Budzinski, Hélène - Castro, Gabriela - den Ouden, Fatima - Dévier, Marie-Hélène - Dulio, Valeria - Feng, Yong-Lai - Gabriel, Marta - Gallampois, Christine - Wang, Xianyu
PY  - 2024
TI  - Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk
JF  - Science of The Total Environment
VL  - 957
IS  - December
SP  - 1-20
EP  - 1-20
PB  - Elsevier B.V.
SN  - 00489697
N1  - Nedoplňovat EF17_043/0009632.
KW  - Geographical trends
KW  - House dust
KW  - Human exposome
KW  - Mass spectrometry
KW  - Organic contaminant profiling
KW  - Risk assessment
UR  - https://doi.org/10.1016/j.scitotenv.2024.177639
N2  - This study investigated the concentration profiles and geographical variability of contaminants in house dust across Europe. A collaborative trial (CT) was organized by the NORMAN network using pooled dust and advanced chromatographic and mass spectrometric techniques combined with suspect screening and non-target screening (NTS). Over 1200 anthropogenic compounds were tentatively identified. Additionally, seventy-five individual samples were subjected to target analysis and NTS. The median concentrations of most contaminants varied <3-fold across Europe, and the contaminant profile of European dust was similar to that of North American dust, which was investigated in a previous CT. This similarity may be attributed to the use of similar consumer articles and building materials throughout the developed world. Multivariate data analysis revealed geographical trends in contaminant distribution, with north-south gradients across Europe. Geographical trends were more frequently found for compounds with rapid release (pharmaceuticals, personal care products, fragrances, pesticides, biocides) and smoke-related compounds. The concentrations of chlorinated paraffins, polycyclic aromatic hydrocarbons (PAHs), perfluorinated alkyl substances and stimulants generally increased from north to south, whereas the biocides levels decreased from north to south. Despite widespread presence of in-use contaminants in dusts, some of the highest risks come from compounds that have been restricted for decades or more. These include di(2-ethylhexyl) phthalate (DEHP), polychlorinated biphenyl (PCB) 118 and polybrominated diphenyl ethers 47, 99, and 153. DEHP remains the most abundant contaminant in European house dust, while the other compounds are classified as persistent organic pollutants (POPs). Moreover, there is a striking lack of reliable toxicity data, particularly for emerging compounds. For instance, although acceptable daily intakes (ADIs) were examined for 202 compounds, only 46 had consensus-based ADI values. The results highlight the need for proactive measures to prevent hazardous chemicals from entering the market and for careful selection of substitute chemicals, when such are needed, to avoid regrettable substitutions.
ER  -

HAGLUND, Peter; Nikiforos A. ALYGIZAKIS; Adrian COVACI; Lisa Emily MELYMUK; Pernilla Bohlin NIZZETTO; Pawel ROSTKOWSKI; Alexandre ALBINET; Sylvana ALIRAI; Dagny AURICH; Stefan BIEBER; Ana BALLESTEROS-GÓMEZ; Amanda A. BRENNAN; Hélène BUDZINSKI; Gabriela CASTRO; Fatima DEN OUDEN; Marie-Hélène DÉVIER; Valeria DULIO; Yong-Lai FENG; Marta GABRIEL; Christine GALLAMPOIS a Xianyu WANG. Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk. \textit{Science of The Total Environment}. Elsevier B.V., 2024, roč.~957, December, s.~1-20. ISSN~0048-9697. Dostupné z: https://doi.org/10.1016/j.scitotenv.2024.177639.

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