Bimetallic nanoparticles: towards selective analysis of
phosphorylated compounds by surface-enhanced Raman spectroscopy

J 2025

Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy

JONAS, Vladimír; Jiří VOLÁNEK; Jan PŘIKRYL a Anna TÝČOVÁ

Základní údaje

Originální název

Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy

Název česky

Bimetalické nanočáctice: směrem k selektivní analýze fosforylovaných sloučenin pomocí povrchově zesílené Ramanovy spektroskopie

Autoři

JONAS, Vladimír; Jiří VOLÁNEK; Jan PŘIKRYL a Anna TÝČOVÁ

Vydání

Nanotechnology, IOP Publishing Ltd, 2025, 0957-4484

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10406 Analytical chemistry

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.800 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/25:00140985

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova česky

bimetalické; nanočístice; fosforylace; povrchem zesílená Ramanova spektrometrie; syntéza; UV-Vis spektrometrie; kompozit

Klíčová slova anglicky

bimetallic; nanoparticles; phosphorylation; surface-enhanced Raman spectroscopy; synthesis; UV-VIS spectrometry; composite

Štítky

14313010, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 4. 2026 10:35, Mgr. Petra Trembecká, Ph.D.

Anotace

V originále

The selective detection of phosphorylated molecules is crucial for various biochemical and analytical applications, yet remains challenging due to their weak Raman signals and limited interactions with conventional SERS substrates. This study presents a novel synthesis strategy for bimetallic Ag/FexOy nanocomposites with ambition for the improved sensitivity and selectivity of SERS detection for phosphorylated compounds. Our approach successfully integrates alkaline precipitation of iron salts with the reduction of silver cations, overcoming the inherent incompatibility of these processes to produce a stable colloid. The resulting nanocomposites feature an architecture that ensures direct analyte interaction with both components: iron oxides selectively capture phosphorylated molecules, while silver provides plasmonic enhancement of the Raman signal. Our findings highlight the critical role of the silver/iron oxides interface in governing SERS sensitivity. This work represents a significant step toward more effective SERS-based detection strategies, with potential applications in real-time analysis using flow-based systems, such as online monitoring after separation techniques in biochemical and medical fields.

Návaznosti

MUNI/A/1691/2024, interní kód MU

Název: Vývoj metod a instrumentace pro chemickou analýzu a studium přírodních a syntetických materiálů včetně biologicky významných látek 2025

Investor: Masarykova univerzita, Vývoj metod a instrumentace pro chemickou analýzu a studium přírodních a syntetických materiálů včetně biologicky významných látek 2025

Citovat

JONAS, Vladimír; Jiří VOLÁNEK; Jan PŘIKRYL a Anna TÝČOVÁ. Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy. Nanotechnology. IOP Publishing Ltd, 2025, roč. 36, č. 18, s. 1-11. ISSN 0957-4484. Dostupné z: https://doi.org/10.1088/1361-6528/adc583.

@article{2490280,
   author = {Jonas, Vladimír and Volánek, Jiří and Přikryl, Jan and Týčová, Anna},
   article_number = {18},
   doi = {https://doi.org/10.1088/1361-6528/adc583},
   keywords = {bimetallic; nanoparticles; phosphorylation; surface-enhanced Raman spectroscopy; synthesis; UV-VIS spectrometry; composite},
   language = {eng},
   issn = {0957-4484},
   journal = {Nanotechnology},
   title = {Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy},
   url = {https://iopscience.iop.org/article/10.1088/1361-6528/adc583},
   volume = {36},
   year = {2025}
}

TY  - JOUR
ID  - 2490280
AU  - Jonas, Vladimír - Volánek, Jiří - Přikryl, Jan - Týčová, Anna
PY  - 2025
TI  - Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy
JF  - Nanotechnology
VL  - 36
IS  - 18
SP  - 1-11
EP  - 1-11
PB  - IOP Publishing Ltd
SN  - 09574484
KW  - bimetallic
KW  - nanoparticles
KW  - phosphorylation
KW  - surface-enhanced Raman spectroscopy
KW  - synthesis
KW  - UV-VIS spectrometry
KW  - composite
UR  - https://iopscience.iop.org/article/10.1088/1361-6528/adc583
N2  - The selective detection of phosphorylated molecules is crucial for various biochemical and analytical applications, yet remains challenging due to their weak Raman signals and limited interactions with conventional SERS substrates. This study presents a novel synthesis strategy for bimetallic Ag/FexOy nanocomposites with ambition for the improved sensitivity and selectivity of SERS detection for phosphorylated compounds. Our approach successfully integrates alkaline precipitation of iron salts with the reduction of silver cations, overcoming the inherent incompatibility of these processes to produce a stable colloid. The resulting nanocomposites feature an architecture that ensures direct analyte interaction with both components: iron oxides selectively capture phosphorylated molecules, while silver provides plasmonic enhancement of the Raman signal. Our findings highlight the critical role of the silver/iron oxides interface in governing SERS sensitivity. This work represents a significant step toward more effective SERS-based detection strategies, with potential applications in real-time analysis using flow-based systems, such as online monitoring after separation techniques in biochemical and medical fields.
ER  -

JONAS, Vladimír; Jiří VOLÁNEK; Jan PŘIKRYL a Anna TÝČOVÁ. Bimetallic nanoparticles: towards selective analysis of phosphorylated compounds by surface-enhanced Raman spectroscopy. \textit{Nanotechnology}. IOP Publishing Ltd, 2025, roč.~36, č.~18, s.~1-11. ISSN~0957-4484. Dostupné z: https://doi.org/10.1088/1361-6528/adc583.

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