Precise Localization of the Subsolid Lesion by Colour Marking
under CT-Guided Control before Video-Assisted Surgery
Resection: A Case Report

J 2025

Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report

ČERVEŇÁK, Vladimír; Zdeněk CHOVANEC; Jan RESLER; Tomáš HANSLÍK; Alena BERKOVÁ et al.

Základní údaje

Originální název

Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report

Název česky

Přesná lokalizace subsolidní léze pomocí barevného značení pod kontrolou CT před video-asistovanou chirurgickou resekcí: kazuistika

Autoři

ČERVEŇÁK, Vladimír; Zdeněk CHOVANEC; Jan RESLER; Tomáš HANSLÍK ; Alena BERKOVÁ; Ondřej BÍLEK; Klára NOVOSÁDOVÁ; Viktor WEISS a Jiří VANÍČEK

Vydání

Case Rep Oncol, Basel, S. Karger AG, 2025, 1662-6575

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30212 Surgery

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.700 v roce 2024

Označené pro přenos do RIV

Ano

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Blue dye marking; Lung cancer; Subsolid nodule; Video-assisted surgery

Štítky

rivok

Příznaky

Recenzováno

Změněno: 5. 3. 2026 15:00, Mgr. Tereza Miškechová

Anotace

V originále

Introduction: Lung cancer is one of the leading causes of death worldwide. Lung lesions, often discovered incidentally on chest CT, pose a diagnostic challenge due to their diverse etiology, including both benign and malignant nature. A key step in the assessment of these lesions is the evaluation of their morphological features in the CT image, size, and behavior over time. Nodules are divided into solid and subsolid according to their density. When surgical resection is necessary, solid lesions are palpable peroperatively, whereas subsolid lesions may be unidentifiable by palpation, and their precise localization is difficult. To spare patients from extensive surgery such as thoracotomy, it is advantageous to use one of the methods of preoperative marking of these lesions. Best practices include marking with mixtures containing patent blue and contrast agents, applied under CT guidance. This method allows accurate visualization of the localization of the lesion, which facilitates their resection by minimally invasive video-assisted surgery (VATS). Case Presentation: A 51-year-old female patient was found to have a subsolid lesion in the right lung during a routine follow-up CT scan of the lung for a history of malignant melanoma. The lesion was followed for 4 years and showed slow size progression and change from a pure ground glass nodule to a subsolid nodule. Due to the persistence of the nodule, change in morphology, and size progression, the patient was indicated for surgical resection. Using preoperative labeling with a mixture of blue dye and contrast agent, the nodule was successfully located and sublobary VATS resected. Conclusion: The color marking allowed accurate identification of the subpleurally located lesion, which would otherwise have been unvisualized and intangible, thus minimizing the need for more extensive surgery. This case highlights the key role of color marking in increasing resection success and surgical safety, particularly in small and subsolid nodules.

Návaznosti

MUNI/A/1692/2024, interní kód MU

Název: Ovlivnění strategie chirurgické léčby u komplikovaných operací II

Investor: Masarykova univerzita, Ovlivnění strategie chirurgické léčby u komplikovaných operací II

Citovat

ČERVEŇÁK, Vladimír; Zdeněk CHOVANEC; Jan RESLER; Tomáš HANSLÍK; Alena BERKOVÁ; Ondřej BÍLEK; Klára NOVOSÁDOVÁ; Viktor WEISS a Jiří VANÍČEK. Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report. Case Rep Oncol. Basel: S. Karger AG, 2025, roč. 18, č. 1, s. 508-514. ISSN 1662-6575. Dostupné z: https://doi.org/10.1159/000545435.

@article{2493821,
   author = {Červeňák, Vladimír and Chovanec, Zdeněk and Resler, Jan and Hanslík, Tomáš and Berková, Alena and Bílek, Ondřej and Novosádová, Klára and Weiss, Viktor and Vaníček, Jiří},
   article_location = {Basel},
   article_number = {1},
   doi = {https://doi.org/10.1159/000545435},
   keywords = {Blue dye marking; Lung cancer; Subsolid nodule; Video-assisted surgery},
   language = {eng},
   issn = {1662-6575},
   journal = {Case Rep Oncol},
   title = {Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report},
   url = {https://karger.com/cro/article/18/1/508/924304/Precise-Localization-of-the-Subsolid-Lesion-by},
   volume = {18},
   year = {2025}
}

TY  - JOUR
ID  - 2493821
AU  - Červeňák, Vladimír - Chovanec, Zdeněk - Resler, Jan - Hanslík, Tomáš - Berková, Alena - Bílek, Ondřej - Novosádová, Klára - Weiss, Viktor - Vaníček, Jiří
PY  - 2025
TI  - Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report
JF  - Case Rep Oncol
VL  - 18
IS  - 1
SP  - 508-514
EP  - 508-514
PB  - S. Karger AG
SN  - 16626575
KW  - Blue dye marking
KW  - Lung cancer
KW  - Subsolid nodule
KW  - Video-assisted surgery
UR  - https://karger.com/cro/article/18/1/508/924304/Precise-Localization-of-the-Subsolid-Lesion-by
N2  - Introduction: Lung cancer is one of the leading causes of death worldwide. Lung lesions, often discovered incidentally on chest CT, pose a diagnostic challenge due to their diverse etiology, including both benign and malignant nature. A key step in the assessment of these lesions is the evaluation of their morphological features in the CT image, size, and behavior over time. Nodules are divided into solid and subsolid according to their density. When surgical resection is necessary, solid lesions are palpable peroperatively, whereas subsolid lesions may be unidentifiable by palpation, and their precise localization is difficult. To spare patients from extensive surgery such as thoracotomy, it is advantageous to use one of the methods of preoperative marking of these lesions. Best practices include marking with mixtures containing patent blue and contrast agents, applied under CT guidance. This method allows accurate visualization of the localization of the lesion, which facilitates their resection by minimally invasive video-assisted surgery (VATS). Case Presentation: A 51-year-old female patient was found to have a subsolid lesion in the right lung during a routine follow-up CT scan of the lung for a history of malignant melanoma. The lesion was followed for 4 years and showed slow size progression and change from a pure ground glass nodule to a subsolid nodule. Due to the persistence of the nodule, change in morphology, and size progression, the patient was indicated for surgical resection. Using preoperative labeling with a mixture of blue dye and contrast agent, the nodule was successfully located and sublobary VATS resected. Conclusion: The color marking allowed accurate identification of the subpleurally located lesion, which would otherwise have been unvisualized and intangible, thus minimizing the need for more extensive surgery. This case highlights the key role of color marking in increasing resection success and surgical safety, particularly in small and subsolid nodules.
ER  -

ČERVEŇÁK, Vladimír; Zdeněk CHOVANEC; Jan RESLER; Tomáš HANSLÍK; Alena BERKOVÁ; Ondřej BÍLEK; Klára NOVOSÁDOVÁ; Viktor WEISS a Jiří VANÍČEK. Precise Localization of the Subsolid Lesion by Colour Marking under CT-Guided Control before Video-Assisted Surgery Resection: A Case Report. \textit{Case Rep Oncol}. Basel: S. Karger AG, 2025, roč.~18, č.~1, s.~508-514. ISSN~1662-6575. Dostupné z: https://doi.org/10.1159/000545435.

Přehled o publikaci