Higher toxicity of ingested metallic lead in a toddler compared
to an adolescent

J 2025

Higher toxicity of ingested metallic lead in a toddler compared to an adolescent

PELCLOVA, Daniela; Petr JABANDŽIEV; Štefánia AULICKÁ a Jan PAPEŽ

Základní údaje

Originální název

Higher toxicity of ingested metallic lead in a toddler compared to an adolescent

Autoři

PELCLOVA, Daniela; Petr JABANDŽIEV; Štefánia AULICKÁ a Jan PAPEŽ

Vydání

Pediatrics International, Wiley, 2025, 1442-200X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30209 Paediatrics

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1111/ped.70039

UT WoS

999

EID Scopus

999

Štítky

14110317, 14110320

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 29. 4. 2025 13:37, Mgr. Tereza Miškechová

Anotace

V originále

Non-occupational sources of lead ingestion may include lead objects, historical ceramics, or old paints. Lead is a cumulative poison with a long elimination half-life of 5–10 years, due to absorption in the bones, where it replaces calcium. Therefore, the intoxication is typically subacute or chronic with anemia, vomiting, constipation, and saturnine colic. In children, due to their less-resistant blood–brain barrier, also lower intellectual quotient may occur. Here we present images documenting ingested lead objects in two patients and a rapid lead absorption in a toddler. Data of two patients who ingested metallic lead objects, the time of their elimination from the gastrointestinal tract (GIT), blood lead level (BLL), hematological and biochemical findings were searched. Finally, the differences in dose and duration of chelation treatment were compared. Required informed consent has been given for both subjects prior to their inclusion in the study. A 14-month-old boy, with body weight (b.w.) 9.8 kg, accidentally swallowed a round metal historical coin, found by his father 1 h earlier in the forest in August 2020. X-ray on the same day revealed it in the stomach. The boy was monitored, and his stool checked, according to European Society of Gastrointestinal Endoscopy Guidelines, which recommend removal if the object is >2.5 cm in diameter.

Citovat

PELCLOVA, Daniela; Petr JABANDŽIEV; Štefánia AULICKÁ a Jan PAPEŽ. Higher toxicity of ingested metallic lead in a toddler compared to an adolescent. Pediatrics International. Wiley, 2025. ISSN 1442-200X. Dostupné z: https://dx.doi.org/10.1111/ped.70039.

@article{2493859,
   author = {Pelclova, Daniela and Jabandžiev, Petr and Aulická, Štefánia and Papež, Jan},
   doi = {http://dx.doi.org/10.1111/ped.70039},
   language = {eng},
   issn = {1442-200X},
   journal = {Pediatrics International},
   title = {Higher toxicity of ingested metallic lead in a toddler compared to an adolescent},
   url = {https://onlinelibrary.wiley.com/doi/10.1111/ped.70039},
   year = {2025}
}

TY  - JOUR
ID  - 2493859
AU  - Pelclova, Daniela - Jabandžiev, Petr - Aulická, Štefánia - Papež, Jan
PY  - 2025
TI  - Higher toxicity of ingested metallic lead in a toddler compared to an adolescent
JF  - Pediatrics International
PB  - Wiley
SN  - 1442200X
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ped.70039
N2  - Non-occupational sources of lead ingestion may include lead objects, historical ceramics, or old paints. Lead is a cumulative poison with a long elimination half-life of 5–10 years, due to absorption in the bones, where it replaces calcium. Therefore, the intoxication is typically subacute or chronic with anemia, vomiting, constipation, and saturnine colic. In children, due to their less-resistant blood–brain barrier, also lower intellectual quotient may occur. Here we present images documenting ingested lead objects in two patients and a rapid lead absorption in a toddler. Data of two patients who ingested metallic lead objects, the time of their elimination from the gastrointestinal tract (GIT), blood lead level (BLL), hematological and biochemical findings were searched. Finally, the differences in dose and duration of chelation treatment were compared. Required informed consent has been given for both subjects prior to their inclusion in the study. A 14-month-old boy, with body weight (b.w.) 9.8 kg, accidentally swallowed a round metal historical coin, found by his father 1 h earlier in the forest in August 2020. X-ray on the same day revealed it in the stomach. The boy was monitored, and his stool checked, according to European Society of Gastrointestinal Endoscopy Guidelines, which recommend removal if the object is >2.5 cm in diameter.
ER  -

PELCLOVA, Daniela; Petr JABANDŽIEV; Štefánia AULICKÁ a Jan PAPEŽ. Higher toxicity of ingested metallic lead in a toddler compared to an adolescent. \textit{Pediatrics International}. Wiley, 2025. ISSN~1442-200X. Dostupné z: https://dx.doi.org/10.1111/ped.70039.

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