Clinical characteristics, management, and predictors of
mortality: results from the national prospective cardiogenic
shock registry (CZECH-SHOCK)

J 2025

Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)

PAZDERNIK, Michal; Petr OSTADAL; Jiri SEINER; Jan PUDIL; Anna CHALOUPKA et al.

Základní údaje

Originální název

Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)

Autoři

Vydání

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, OXFORD, OXFORD UNIV PRESS, 2025, 2048-8726

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.600 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/25:00141315

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Cardiogenic shock; CZECH-SHOCK; AMI-CS; Shock registry; Mortality

Štítky

14110115, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 2. 2026 12:14, Mgr. Tereza Miškechová

Anotace

V originále

Aims Only limited epidemiological data exist from national or international prospective multicentre registries covering the whole spectrum of cardiogenic shock (CS) aetiologies.Methods and results A national prospective multicentre observational study, CZECH-SHOCK, was conducted in 15 main tertiary care centres in Czechia over a 12 month period from March 2023 to February 2024. A total of 418 patients with a median age of 70 (interquartile range 59-76) years were enrolled. The majority of patients was males (69.6%). A newly developed heart failure was observed in 76.8% patients, and acute myocardial infarction complicated by CS was the most frequent cause of a CS episode (56.7%). Mechanical circulatory support devices were utilized in 28.2% of cases. A 30 day mortality was 39.5%. In a multivariate analysis, six independent factors were associated with a higher 30 day mortality: age [odds ratio (OR) per 10-year increase: 1.78, 95% confidence interval (CI): 1.45-2.19], history of coronary artery disease (OR: 2.38, 95% CI: 1.41-4.30), history of chronic obstructive pulmonary disease (OR: 2.58, 95% CI: 1.27-5.25), Society for Cardiovascular Angiography and Interventions class on admission (OR per one class increase: 1.64, 95% CI: 1.27-2.11), renal replacement therapy during in-hospital stay (OR: 2.46, 95% CI: 1.32-4.59), and new mechanical ventilation after admission (OR: 4.58, 95% CI: 2.50-8.39).Conclusion Acute myocardial infarction complicated by CS still represents the most frequent cause of CS episodes. The in-hospital mortality of patients with CS remains high, despite frequent utilization of haemodynamic support and organ replacement therapies.

Citovat

PAZDERNIK, Michal; Petr OSTADAL; Jiri SEINER; Jan PUDIL; Anna CHALOUPKA; Martin NOVÁK; Eva LICHNEROVA; Radek PELOUCH; Dagmar VONDRAKOVA; Aneta DVORAKOVA; David FORAL; Ales KOVARIK; Tomas HNAT; Ahmad ZOHOOR; Adam POCAROVSKY; Aneta HAINZOVA; Jan MATEJKA; Ondrej SIROTEK; Anna VALERIANOVA; Martin VOJTISEK; Jan PRECEK; Peter MISUN; Marek SRAMKO; Jan MARES a Jan BELOHLAVEK. Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK). EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. OXFORD: OXFORD UNIV PRESS, 2025, roč. 14, č. 6, s. 359-363. ISSN 2048-8726. Dostupné z: https://doi.org/10.1093/ehjacc/zuaf034.

@article{2501038,
   author = {Pazdernik, Michal and Ostadal, Petr and Seiner, Jiri and Pudil, Jan and Chaloupka, Anna and Novák, Martin and Lichnerova, Eva and Pelouch, Radek and Vondrakova, Dagmar and Dvorakova, Aneta and Foral, David and Kovarik, Ales and Hnat, Tomas and Zohoor, Ahmad and Pocarovsky, Adam and Hainzova, Aneta and Matejka, Jan and Sirotek, Ondrej and Valerianova, Anna and Vojtisek, Martin and Precek, Jan and Misun, Peter and Sramko, Marek and Mares, Jan and Belohlavek, Jan},
   article_location = {OXFORD},
   article_number = {6},
   doi = {https://doi.org/10.1093/ehjacc/zuaf034},
   keywords = {Cardiogenic shock; CZECH-SHOCK; AMI-CS; Shock registry; Mortality},
   language = {eng},
   issn = {2048-8726},
   journal = {EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE},
   title = {Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)},
   url = {https://academic.oup.com/ehjacc/advance-article/doi/10.1093/ehjacc/zuaf034/8046213?login=true},
   volume = {14},
   year = {2025}
}

TY  - JOUR
ID  - 2501038
AU  - Pazdernik, Michal - Ostadal, Petr - Seiner, Jiri - Pudil, Jan - Chaloupka, Anna - Novák, Martin - Lichnerova, Eva - Pelouch, Radek - Vondrakova, Dagmar - Dvorakova, Aneta - Foral, David - Kovarik, Ales - Hnat, Tomas - Zohoor, Ahmad - Pocarovsky, Adam - Hainzova, Aneta - Matejka, Jan - Sirotek, Ondrej - Valerianova, Anna - Vojtisek, Martin - Precek, Jan - Misun, Peter - Sramko, Marek - Mares, Jan - Belohlavek, Jan
PY  - 2025
TI  - Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)
JF  - EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
VL  - 14
IS  - 6
SP  - 359-363
EP  - 359-363
PB  - OXFORD UNIV PRESS
SN  - 20488726
KW  - Cardiogenic shock
KW  - CZECH-SHOCK
KW  - AMI-CS
KW  - Shock registry
KW  - Mortality
UR  - https://academic.oup.com/ehjacc/advance-article/doi/10.1093/ehjacc/zuaf034/8046213?login=true
N2  - Aims Only limited epidemiological data exist from national or international prospective multicentre registries covering the whole spectrum of cardiogenic shock (CS) aetiologies.Methods and results A national prospective multicentre observational study, CZECH-SHOCK, was conducted in 15 main tertiary care centres in Czechia over a 12 month period from March 2023 to February 2024. A total of 418 patients with a median age of 70 (interquartile range 59-76) years were enrolled. The majority of patients was males (69.6%). A newly developed heart failure was observed in 76.8% patients, and acute myocardial infarction complicated by CS was the most frequent cause of a CS episode (56.7%). Mechanical circulatory support devices were utilized in 28.2% of cases. A 30 day mortality was 39.5%. In a multivariate analysis, six independent factors were associated with a higher 30 day mortality: age [odds ratio (OR) per 10-year increase: 1.78, 95% confidence interval (CI): 1.45-2.19], history of coronary artery disease (OR: 2.38, 95% CI: 1.41-4.30), history of chronic obstructive pulmonary disease (OR: 2.58, 95% CI: 1.27-5.25), Society for Cardiovascular Angiography and Interventions class on admission (OR per one class increase: 1.64, 95% CI: 1.27-2.11), renal replacement therapy during in-hospital stay (OR: 2.46, 95% CI: 1.32-4.59), and new mechanical ventilation after admission (OR: 4.58, 95% CI: 2.50-8.39).Conclusion Acute myocardial infarction complicated by CS still represents the most frequent cause of CS episodes. The in-hospital mortality of patients with CS remains high, despite frequent utilization of haemodynamic support and organ replacement therapies.
ER  -

PAZDERNIK, Michal; Petr OSTADAL; Jiri SEINER; Jan PUDIL; Anna CHALOUPKA; Martin NOVÁK; Eva LICHNEROVA; Radek PELOUCH; Dagmar VONDRAKOVA; Aneta DVORAKOVA; David FORAL; Ales KOVARIK; Tomas HNAT; Ahmad ZOHOOR; Adam POCAROVSKY; Aneta HAINZOVA; Jan MATEJKA; Ondrej SIROTEK; Anna VALERIANOVA; Martin VOJTISEK; Jan PRECEK; Peter MISUN; Marek SRAMKO; Jan MARES a Jan BELOHLAVEK. Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK). \textit{EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE}. OXFORD: OXFORD UNIV PRESS, 2025, roč.~14, č.~6, s.~359-363. ISSN~2048-8726. Dostupné z: https://doi.org/10.1093/ehjacc/zuaf034.

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