Immunochemical Applications Utilizing Laser-Induced Breakdown
Spectroscopy Detection

C 2025

Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection

ZIKMUNDOVÁ, Eva; Pavlína MODLITBOVÁ; Pavel POŘÍZKA; Zdeněk FARKA; Michaela KUCHYNKA et al.

Základní údaje

Originální název

Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection

Autoři

ZIKMUNDOVÁ, Eva; Pavlína MODLITBOVÁ; Pavel POŘÍZKA; Zdeněk FARKA; Michaela KUCHYNKA; Karel NOVOTNÝ a Jozef KAISER

Vydání

Cham, Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences, od s. 331-356, 26 s. Second Edition, 2025

Nakladatel

Springer

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10406 Analytical chemistry

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/25:00144353

Organizační jednotka

Přírodovědecká fakulta

ISBN

978-3-031-85974-8

DOI

https://doi.org/10.1007/978-3-031-85975-5_11

EID Scopus

2-s2.0-105022376781

Klíčová slova anglicky

laser-induced breakdown spectroscopy; LIBS; immunoassay; label; nanoparticle; laser ablation inductively coupled plasma mass spectrometry

Štítky

14313010, 14313050

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 1. 2. 2026 15:05, doc. Mgr. Zdeněk Farka, Ph.D.

Anotace

V originále

Immunochemistry specifically detects or visualizes biologically important analytes, such as disease biomarkers or pathogens, employing various detection techniques. This can be done by employing label-based assays for indirect detection of the analytes. The labels for immunochemical methods, typically with luminescence or enzymatic properties, are selected to allow a simple and fast detection, high accuracy, and reproducibility of the measurements. In this chapter, immunochemical methodology based on laser-induced breakdown spectroscopy (LIBS) detection is mainly discussed in comparison with other commonly used techniques based on luminescence or color change monitoring. Being a multielemental analytical technique, LIBS allows for the differentiation of the labels based on their elemental composition with no need for specific label properties (e.g., luminescence) while maintaining the information on the distribution of other valuable constituents. For the sake of complementarity, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) as a detection technique for immunochemical methods is also included in the chapter as it serves not only as a reference for the tag-LIBS technique. With the continual advancement of the instrumentation of both techniques, the possibility of a tandem analysis by tag-LIBS and LA-ICP-MS might be explored in the future.

Návaznosti

GA22-27580S, projekt VaV

Název: Laserová spektroskopie v imunostanovení a zobrazování s nanometalickými značkami (Akronym: IMMUNOLIBS)

Investor: Grantová agentura ČR, Laserová spektroskopie v imunostanovení a zobrazování s nanometalickými značkami

Citovat

ZIKMUNDOVÁ, Eva; Pavlína MODLITBOVÁ; Pavel POŘÍZKA; Zdeněk FARKA; Michaela KUCHYNKA; Karel NOVOTNÝ a Jozef KAISER. Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection. In Gábor Galbács. Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences. Cham: Springer, 2025, s. 331-356. Second Edition. ISBN 978-3-031-85974-8. Dostupné z: https://doi.org/10.1007/978-3-031-85975-5_11.

@inbook{2504540,
   author = {Zikmundová, Eva and Modlitbová, Pavlína and Pořízka, Pavel and Farka, Zdeněk and Kuchynka, Michaela and Novotný, Karel and Kaiser, Jozef},
   address = {Cham},
   booktitle = {Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences},
   doi = {https://doi.org/10.1007/978-3-031-85975-5_11},
   editor = {Gábor Galbács},
   keywords = {laser-induced breakdown spectroscopy; LIBS; immunoassay; label; nanoparticle; laser ablation inductively coupled plasma mass spectrometry},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Cham},
   isbn = {978-3-031-85974-8},
   pages = {331-356},
   publisher = {Springer},
   title = {Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection},
   url = {https://link.springer.com/chapter/10.1007/978-3-031-85975-5_11},
   year = {2025}
}

TY  - CHAP
ID  - 2504540
AU  - Zikmundová, Eva - Modlitbová, Pavlína - Pořízka, Pavel - Farka, Zdeněk - Kuchynka, Michaela - Novotný, Karel - Kaiser, Jozef
PY  - 2025
TI  - Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection
VL  - Second Edition
PB  - Springer
CY  - Cham
SN  - 9783031859748
KW  - laser-induced breakdown spectroscopy
KW  - LIBS
KW  - immunoassay
KW  - label
KW  - nanoparticle
KW  - laser ablation inductively coupled plasma mass spectrometry
UR  - https://link.springer.com/chapter/10.1007/978-3-031-85975-5_11
N2  - Immunochemistry specifically detects or visualizes biologically important analytes, such as disease biomarkers or pathogens, employing various detection techniques. This can be done by employing label-based assays for indirect detection of the analytes. The labels for immunochemical methods, typically with luminescence or enzymatic properties, are selected to allow a simple and fast detection, high accuracy, and reproducibility of the measurements. In this chapter, immunochemical methodology based on laser-induced breakdown spectroscopy (LIBS) detection is mainly discussed in comparison with other commonly used techniques based on luminescence or color change monitoring. Being a multielemental analytical technique, LIBS allows for the differentiation of the labels based on their elemental composition with no need for specific label properties (e.g., luminescence) while maintaining the information on the distribution of other valuable constituents. For the sake of complementarity, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) as a detection technique for immunochemical methods is also included in the chapter as it serves not only as a reference for the tag-LIBS technique. With the continual advancement of the instrumentation of both techniques, the possibility of a tandem analysis by tag-LIBS and LA-ICP-MS might be explored in the future.
ER  -

ZIKMUNDOVÁ, Eva; Pavlína MODLITBOVÁ; Pavel POŘÍZKA; Zdeněk FARKA; Michaela KUCHYNKA; Karel NOVOTNÝ a Jozef KAISER. Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection. In Gábor Galbács. \textit{Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences}. Cham: Springer, 2025, s.~331-356. Second Edition. ISBN~978-3-031-85974-8. Dostupné z: https://doi.org/10.1007/978-3-031-85975-5\_{}11.

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