Technological development of bioequivalent omeprazole product

a 2025

Technological development of bioequivalent omeprazole product

VETCHÝ, David; Gulzina KUMISBEK; Jiří ZEMAN; Miroslava PAVELKOVÁ; Kateřina KUBOVÁ et al.

Základní údaje

Originální název

Technological development of bioequivalent omeprazole product

Autoři

VETCHÝ, David; Gulzina KUMISBEK; Jiří ZEMAN ; Miroslava PAVELKOVÁ a Kateřina KUBOVÁ

Vydání

15th Central European Symposium on Pharmaceutical Technology, 2025

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Slovinsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Kniha abstraktů

Označené pro přenos do RIV

Organizační jednotka

Farmaceutická fakulta

ISBN

978-961-97122-0-7

Klíčová slova česky

omeprazol; generikum; inhibitor protonové pumpy; bioekvivalence; obalování; pelety

Klíčová slova anglicky

omeprazole; generic drug; bioquivalence; proton pump inhibitor; coating; pellets

Příznaky

Mezinárodní význam

Změněno: 20. 3. 2026 12:36, Mgr. Irena Doubková

Anotace

V originále

Proton pump inhibitors (PPIs) are the primary drugs used to treat acid-related diseases of the upper gastrointestinal tract due to their highly selective inhibitory effect on the acid-forming function of the stomach. The primary drug from the PPI group is omeprazole, which was synthesized in 1979 after discovering a unique enzyme, K+-stimulated ATPase, in parietal cells during experiments on the gastric mucosa [1]. In 2023, omeprazole was found to be the third most commonly prescribed chemical substance in England, with the drug listed on approximately 35 million prescriptions [2]. The localization of pharmaceutical drug production is one of Europe's primary strategies to ensure that the population has access to affordable and good-quality medicines. This study describes the technological development of bioequivalent delayed-release omeprazole.

Citovat

VETCHÝ, David; Gulzina KUMISBEK; Jiří ZEMAN; Miroslava PAVELKOVÁ a Kateřina KUBOVÁ. Technological development of bioequivalent omeprazole product. In 15th Central European Symposium on Pharmaceutical Technology. 2025. ISBN 978-961-97122-0-7.

@proceedings{2529621,
   author = {Vetchý, David and Kumisbek, Gulzina and Zeman, Jiří and Pavelková, Miroslava and Kubová, Kateřina},
   booktitle = {15th Central European Symposium on Pharmaceutical Technology},
   keywords = {omeprazole; generic drug; bioquivalence; proton pump inhibitor; coating; pellets},
   language = {eng},
   isbn = {978-961-97122-0-7},
   title = {Technological development of bioequivalent omeprazole product},
   url = {https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf},
   year = {2025}
}

TY  - CONF
ID  - 2529621
AU  - Vetchý, David - Kumisbek, Gulzina - Zeman, Jiří - Pavelková, Miroslava - Kubová, Kateřina
PY  - 2025
TI  - Technological development of bioequivalent omeprazole product
SN  - 9789619712207
KW  - omeprazole
KW  - generic drug
KW  - bioquivalence
KW  - proton pump inhibitor
KW  - coating
KW  - pellets
UR  - https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf
N2  - Proton pump inhibitors (PPIs) are the primary drugs used to treat acid-related diseases of the upper gastrointestinal tract due to their highly selective inhibitory effect on the acid-forming function of the stomach. The primary drug from the PPI group is omeprazole, which was synthesized in 1979 after discovering a unique enzyme, K+-stimulated ATPase, in parietal cells during experiments on the gastric mucosa [1]. In 2023, omeprazole was found to be the third most commonly prescribed chemical substance in England, with the drug listed on approximately 35 million prescriptions [2]. The localization of pharmaceutical drug production is one of Europe's primary strategies to ensure that the population has access to affordable and good-quality medicines. This study describes the technological development of bioequivalent delayed-release omeprazole.
ER  -

VETCHÝ, David; Gulzina KUMISBEK; Jiří ZEMAN; Miroslava PAVELKOVÁ a Kateřina KUBOVÁ. Technological development of bioequivalent omeprazole product. In \textit{15th Central European Symposium on Pharmaceutical Technology}. 2025. ISBN~978-961-97122-0-7.

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