Orangutan herbal remedies: lessons for human health

k 2025

Orangutan herbal remedies: lessons for human health

FOITOVÁ, Ivona; Radka PECKOVÁ; Karel DOLEŽAL; Wisnu NURCAHYO; Milan OLŠANSKÝ et al.

Základní údaje

Originální název

Orangutan herbal remedies: lessons for human health

Autoři

FOITOVÁ, Ivona; Radka PECKOVÁ; Karel DOLEŽAL; Wisnu NURCAHYO a Milan OLŠANSKÝ

Vydání

Phytochemicals as Drugs, Foods and Biocommunicators, 2025

Další údaje

Jazyk

angličtina

Typ výsledku

Prezentace na konferencích

Obor

10606 Microbiology

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/25:00144499

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

self-medication; ; anti-parasitic activity; orangutan; in vitro tests

Štítky

14314020

Příznaky

Mezinárodní význam

Změněno: 4. 11. 2025 09:27, Mgr. Radka Pecková, Ph.D.

Anotace

V originále

Both human and animal health are continually threatened by infectious diseases. The “One Health concept” has highlighted the strong interrelation between human and animal health in recent years. Understanding factors affecting individual health is crucial for determining the underlying health and resilience of the International Congress on Natural Products Research 2024 Phytochemistry Letters 69 (2025) 102917 46 environment. The health of both individuals and ecosystems depends on homeostasis, the balancing of dynamic processes through continuous interaction and feedback within the integrated system. Parasites play a significant role in individual, species, and ecosystem health. Given the phylogenetic similarities between humans and orangutans, studying orangutan feeding behavior is relevant, particularly regarding specific plant foods consumed to combat parasitic infections. Orangutans, the only ape species in Southeast Asia, face critical endangerment, listed as such by the IUCN. Self-medication in primates sheds new light into the complex interactions of the animal, plant and parasite. While primates consume a variety of nonnutritional plant compounds and nutrient-poor bark, little is understood about the potential medicinal benefits of such ingestion. Our recent research confirms self- medication in orangutans (Pongo pygmaeus) for the first time, based on pharmacological analyses. Several plants in the orangutan diet hold potential medicinal value, some used in traditional human medicine. This presentation will explore plants within the orangutan diet that demonstrate effectiveness against parasites through in vitro testing, such as Piper betle, Archidendron fagifollium, Mimosa sp., Knema laurina. Our findings, along with descriptions of plant species exhibiting novel antiparasitic effects, may inform drug development efforts to combat infectious diseases in both human and animal populations.

Návaznosti

GA23-06571S, projekt VaV

Název: Co nás mohou naučit orangutani: protiamébová a protigiardiová aktivita rostlin používaných orangutany k možné sebemedikaci

Investor: Grantová agentura ČR, What orangutans can teach us: plants used for self-medication as a potential source of bioactive substances with amoebicidal and antigiardial effects

Citovat

FOITOVÁ, Ivona; Radka PECKOVÁ; Karel DOLEŽAL; Wisnu NURCAHYO a Milan OLŠANSKÝ. Orangutan herbal remedies: lessons for human health. In Phytochemicals as Drugs, Foods and Biocommunicators. 2025.

@proceedings{2530498,
   author = {Foitová, Ivona and Pecková, Radka and Doležal, Karel and Nurcahyo, Wisnu and Olšanský, Milan},
   booktitle = {Phytochemicals as Drugs, Foods and Biocommunicators},
   keywords = {self-medication; ; anti-parasitic activity; orangutan; in vitro tests},
   language = {eng},
   title = {Orangutan herbal remedies: lessons for human health},
   url = {https://www.sciencedirect.com/science/article/pii/S1874390025012364?via%3Dihub},
   year = {2025}
}

TY  - CONF
ID  - 2530498
AU  - Foitová, Ivona - Pecková, Radka - Doležal, Karel - Nurcahyo, Wisnu - Olšanský, Milan
PY  - 2025
TI  - Orangutan herbal remedies: lessons for human health
KW  - self-medication
KW  -
KW  - anti-parasitic activity
KW  - orangutan
KW  - in vitro tests
UR  - https://www.sciencedirect.com/science/article/pii/S1874390025012364?via%3Dihub
N2  - Both human and animal health are continually threatened by infectious diseases. The “One Health concept” has highlighted the strong interrelation between human and animal health in recent years. Understanding factors affecting individual health is crucial for determining the underlying health and resilience of the International Congress on Natural Products Research 2024 Phytochemistry Letters 69 (2025) 102917 46 environment. The health of both individuals and ecosystems depends on homeostasis, the balancing of dynamic processes through continuous interaction and feedback within the integrated system. Parasites play a significant role in individual, species, and ecosystem health. Given the phylogenetic similarities between humans and orangutans, studying orangutan feeding behavior is relevant, particularly regarding specific plant foods consumed to combat parasitic infections. Orangutans, the only ape species in Southeast Asia, face critical endangerment, listed as such by the IUCN. Self-medication in primates sheds new light into the complex interactions of the animal, plant and parasite. While primates consume a variety of nonnutritional plant compounds and nutrient-poor bark, little is understood about the potential medicinal benefits of such ingestion. Our recent research confirms self- medication in orangutans (Pongo pygmaeus) for the first time, based on pharmacological analyses. Several plants in the orangutan diet hold potential medicinal value, some used in traditional human medicine. This presentation will explore plants within the orangutan diet that demonstrate effectiveness against parasites through in vitro testing, such as Piper betle, Archidendron fagifollium, Mimosa sp., Knema laurina. Our findings, along with descriptions of plant species exhibiting novel antiparasitic effects, may inform drug development efforts to combat infectious diseases in both human and animal populations.
ER  -

FOITOVÁ, Ivona; Radka PECKOVÁ; Karel DOLEŽAL; Wisnu NURCAHYO a Milan OLŠANSKÝ. Orangutan herbal remedies: lessons for human health. In \textit{Phytochemicals as Drugs, Foods and Biocommunicators}. 2025.

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