Unlocking Alimentary Transmission: How Milk Components Modulate
Tick-Borne Encephalitis Virus Stability

a 2025

Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability

MACHÁČEK, Martin; Michaela BERÁNKOVÁ; Jiří SALÁT a Daniel RŮŽEK

Základní údaje

Originální název

Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability

Autoři

MACHÁČEK, Martin; Michaela BERÁNKOVÁ; Jiří SALÁT a Daniel RŮŽEK

Vydání

International One Health Symposium, Berlin, 2025

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

10607 Virology

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova česky

virus klíšťové encefalitidy; alimentární infekce; mléko

Klíčová slova anglicky

tick-borne encephalitis virus; alimentary infection; milk

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 11. 2025 07:13, Mgr. Michaela Beránková

Anotace

V originále

Tick-borne encephalitis virus (TBEV) is not only transmitted by ticks but also via contaminated dairy products—a route that remains underappreciated despite its public health relevance. We explored how milk shapes viral survival in the digestive tract using simulated gastrointestinal conditions. Although milk can preserve TBEV infectivity at low temperatures, it acts very differently in the gastric environment, where it reduces viral stability and viability. This effect, driven by whey, casein, and lipids, suggests that rapid gastric transit is critical for successful infection. In the intestine, milk shields TBEV against bile salt–mediated inactivation, with casein emerging as the key protective factor. Thus, milk plays a dual role in TBEV alimentary transmission, limiting survival in the stomach but supporting persistence in the intestine. Our findings shed new light on how dietary components modulate viral stability, providing critical insights into the overlooked risk of foodborne tick-borne encephalitis.

Citovat

MACHÁČEK, Martin; Michaela BERÁNKOVÁ; Jiří SALÁT a Daniel RŮŽEK. Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability. In International One Health Symposium, Berlin. 2025.

@proceedings{2534397,
   author = {Macháček, Martin and Beránková, Michaela and Salát, Jiří and Růžek, Daniel},
   booktitle = {International One Health Symposium, Berlin},
   keywords = {tick-borne encephalitis virus; alimentary infection; milk},
   language = {eng},
   title = {Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability},
   url = {https://evis.events/event/571/contributions/5270/},
   year = {2025}
}

TY  - CONF
ID  - 2534397
AU  - Macháček, Martin - Beránková, Michaela - Salát, Jiří - Růžek, Daniel
PY  - 2025
TI  - Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability
KW  - tick-borne encephalitis virus
KW  - alimentary infection
KW  - milk
UR  - https://evis.events/event/571/contributions/5270/
N2  - Tick-borne encephalitis virus (TBEV) is not only transmitted by ticks but also via contaminated dairy products—a route that remains underappreciated despite its public health relevance. We explored how milk shapes viral survival in the digestive tract using simulated gastrointestinal conditions. Although milk can preserve TBEV infectivity at low temperatures, it acts very differently in the gastric environment, where it reduces viral stability and viability. This effect, driven by whey, casein, and lipids, suggests that rapid gastric transit is critical for successful infection. In the intestine, milk shields TBEV against bile salt–mediated inactivation, with casein emerging as the key protective factor. Thus, milk plays a dual role in TBEV alimentary transmission, limiting survival in the stomach but supporting persistence in the intestine. Our findings shed new light on how dietary components modulate viral stability, providing critical insights into the overlooked risk of foodborne tick-borne encephalitis.
ER  -

MACHÁČEK, Martin; Michaela BERÁNKOVÁ; Jiří SALÁT a Daniel RŮŽEK. Unlocking Alimentary Transmission: How Milk Components Modulate Tick-Borne Encephalitis Virus Stability. In \textit{International One Health Symposium, Berlin}. 2025.

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