Antimicrobials Shape the Gut Microbiome Structure and Digestive
Profile of Invertebrates

J 2025

Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates

FECKLER, Alexander; Eric BOLLINGER; Sven KATZENMEIER; Ondřej ADAMOVSKÝ; Hana VESPALCOVÁ et al.

Základní údaje

Originální název

Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates

Autoři

FECKLER, Alexander; Eric BOLLINGER; Sven KATZENMEIER; Ondřej ADAMOVSKÝ; Hana VESPALCOVÁ; Eva BUDINSKÁ; Thorsten STOECK a Mirco BUNDSCHUH

Vydání

ENVIRONMENTAL SCIENCE & TECHNOLOGY, WASHINGTON, DC (USA), AMER CHEMICAL SOC, 2025, 0013-936X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 11.300 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/25:00142634

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

antibiotic; detritivore; endosymbiont; fungi; fungicide; microbiome; prokaryotes

Štítky

143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 2. 2026 09:23, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

The gut microbiome is crucial for host well-being but is vulnerable to external stressors, such as antimicrobials. This study examined how an antibiotic, a fungicide, and their mixture affect the prokaryotic and fungal gut microbiome in Gammarus fossarum via dietary, waterborne, and combined exposure. Antimicrobial exposure altered the relative abundance of bacterial classes, including Verrucomicrobiae, Alphaproteobacteria, Betaproteobacteria, and Gammaproteobacteria, with effect directions depending on the antimicrobial. These structural shifts were predicted to enhance lipid and energy metabolism, particularly under dietary and combined exposure, potentially influencing host physiology. Previous studies on the same species reported up to 25% higher biomass gain under these exposure routes, whereas waterborne exposure had negligible effects. As this study primarily relies on predictive models linking microbiome shifts to physiological changes, experimental validation is required to substantiate these findings. Likewise, several fungal classes were affected, but limited knowledge of the mycobiome hinders functional interpretation. Overall, dietary uptake emerged as a key driver of gut microbiome changes, while waterborne exposure played a minor role in the metabolic and physiological responses. Future research should investigate the mycobiome alongside its prokaryotic counterpart for a more comprehensive understanding of the gut digestive profile of invertebrates as a whole and its role in host health.

Návaznosti

101057014, interní kód MU

Název: Partnership for the Assessment of Risks from Chemicals (Akronym: PARC)

Investor: Evropská unie, Partnership for the Assessment of Risks from Chemicals, Klastr 1 - Zdraví

857560, interní kód MU
(Kód CEP: EF17_043/0009632)

Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)

Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation

90269, velká výzkumná infrastruktura

Název: RECETOX RI II

Citovat

FECKLER, Alexander; Eric BOLLINGER; Sven KATZENMEIER; Ondřej ADAMOVSKÝ; Hana VESPALCOVÁ; Eva BUDINSKÁ; Thorsten STOECK a Mirco BUNDSCHUH. Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates. ENVIRONMENTAL SCIENCE & TECHNOLOGY. WASHINGTON, DC (USA): AMER CHEMICAL SOC, 2025, roč. 59, č. 37, s. 19667-19676. ISSN 0013-936X. Dostupné z: https://doi.org/10.1021/acs.est.5c04159.

@article{2534472,
   author = {Feckler, Alexander and Bollinger, Eric and Katzenmeier, Sven and Adamovský, Ondřej and Vespalcová, Hana and Budinská, Eva and Stoeck, Thorsten and Bundschuh, Mirco},
   article_location = {WASHINGTON, DC (USA)},
   article_number = {37},
   doi = {https://doi.org/10.1021/acs.est.5c04159},
   keywords = {antibiotic; detritivore; endosymbiont; fungi; fungicide; microbiome; prokaryotes},
   language = {eng},
   issn = {0013-936X},
   journal = {ENVIRONMENTAL SCIENCE & TECHNOLOGY},
   title = {Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates},
   url = {https://pubs.acs.org/doi/10.1021/acs.est.5c04159?src=getftr&utm_source=clarivate&getft_integrator=clarivate},
   volume = {59},
   year = {2025}
}

TY  - JOUR
ID  - 2534472
AU  - Feckler, Alexander - Bollinger, Eric - Katzenmeier, Sven - Adamovský, Ondřej - Vespalcová, Hana - Budinská, Eva - Stoeck, Thorsten - Bundschuh, Mirco
PY  - 2025
TI  - Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates
JF  - ENVIRONMENTAL SCIENCE & TECHNOLOGY
VL  - 59
IS  - 37
SP  - 19667-19676
EP  - 19667-19676
PB  - AMER CHEMICAL SOC
SN  - 0013936X
KW  - antibiotic
KW  - detritivore
KW  - endosymbiont
KW  - fungi
KW  - fungicide
KW  - microbiome
KW  - prokaryotes
UR  - https://pubs.acs.org/doi/10.1021/acs.est.5c04159?src=getftr&utm_source=clarivate&getft_integrator=clarivate
N2  - The gut microbiome is crucial for host well-being but is vulnerable to external stressors, such as antimicrobials. This study examined how an antibiotic, a fungicide, and their mixture affect the prokaryotic and fungal gut microbiome in Gammarus fossarum via dietary, waterborne, and combined exposure. Antimicrobial exposure altered the relative abundance of bacterial classes, including Verrucomicrobiae, Alphaproteobacteria, Betaproteobacteria, and Gammaproteobacteria, with effect directions depending on the antimicrobial. These structural shifts were predicted to enhance lipid and energy metabolism, particularly under dietary and combined exposure, potentially influencing host physiology. Previous studies on the same species reported up to 25% higher biomass gain under these exposure routes, whereas waterborne exposure had negligible effects. As this study primarily relies on predictive models linking microbiome shifts to physiological changes, experimental validation is required to substantiate these findings. Likewise, several fungal classes were affected, but limited knowledge of the mycobiome hinders functional interpretation. Overall, dietary uptake emerged as a key driver of gut microbiome changes, while waterborne exposure played a minor role in the metabolic and physiological responses. Future research should investigate the mycobiome alongside its prokaryotic counterpart for a more comprehensive understanding of the gut digestive profile of invertebrates as a whole and its role in host health.
ER  -

FECKLER, Alexander; Eric BOLLINGER; Sven KATZENMEIER; Ondřej ADAMOVSKÝ; Hana VESPALCOVÁ; Eva BUDINSKÁ; Thorsten STOECK a Mirco BUNDSCHUH. Antimicrobials Shape the Gut Microbiome Structure and Digestive Profile of Invertebrates. \textit{ENVIRONMENTAL SCIENCE \&{}amp; TECHNOLOGY}. WASHINGTON, DC (USA): AMER CHEMICAL SOC, 2025, roč.~59, č.~37, s.~19667-19676. ISSN~0013-936X. Dostupné z: https://doi.org/10.1021/acs.est.5c04159.

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