Dermatomal Contact Heat Evoked Potentials for the Detection of
Subclinical Cervical Spinal Cord Injury in Asymptomatic
Degenerative Cervical Cord Compression

J 2025

Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression

JOPPEKOVÁ, Ľubica; Adam BETÍK; Lucia BAKOŠOVÁ; Iva ŠROTOVÁ; Tomáš ROHAN et al.

Základní údaje

Originální název

Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression

Autoři

JOPPEKOVÁ, Ľubica; Adam BETÍK; Lucia BAKOŠOVÁ; Iva ŠROTOVÁ; Tomáš ROHAN; Miloš KEŘKOVSKÝ; Marek DOSTÁL; Jan ŠTULÍK; Martin NEMEC; Jan VALOSEK; Eva VLČKOVÁ a Josef BEDNAŘÍK

Vydání

European Journal of Neurology, Hoboken, Wiley, 2025, 1351-5101

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.900 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/25:00143409

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

electromyography; evoked potentials; magnetic resonance imaging; spinal cord compression; spinal cord diseases

Štítky

14110216, 14110221, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 19. 1. 2026 09:46, Mgr. Tereza Miškechová

Anotace

V originále

Background Asymptomatic degenerative cervical cord compression (ADCC) represents a premyelopathic stage of degenerative cervical myelopathy (DCM), with high prevalence in older age and unclear management. Contact heat-evoked potentials (CHEPs) assess the integrity of the thermo-algesic somatosensory pathway and have shown the highest sensitivity among neurophysiological methods in detecting dysfunction in the centromedial and anterior spinal cord in DCM. Methods This cross-sectional cohort study evaluated the utility of upper extremity dermatomal C4, C6 and C8 CHEPs (dCHEPs) compared to standard neurophysiological methods-median and tibial nerves somatosensory evoked potentials (SEPs), upper and lower extremity motor evoked potentials (MEPs), and electromyography (EMG)-for detecting subclinical cervical cord dysfunction in ADCC. Two cohorts were included: 82 ADCC patients (mean age 53.7 +/- 9.8 years; 53 females) and 10 DCM patients (mean age 64.0 +/- 7.9 years; 4 females). All underwent bilateral dCHEPs (C4, C6, C8), SEPs, MEPs, and EMG (C5-C8 myotomes). Results dCHEPs abnormalities were found in 50% of ADCC patients, exceeding the rates for SEPs (32.1%), MEPs (21.8%), and EMG (13.9%). In 20.7%, dCHEPs were the only abnormal neurophysiological finding. In the DCM cohort, dCHEPs were abnormal in 80%, and were the only abnormality in 20%. In both groups, abnormalities were most frequent in the C8 dermatome. Conclusions dCHEPs demonstrated superior sensitivity in detecting cervical cord dysfunction, not only in DCM but also in ADCC. As a functional complement to MRI, they may aid in identifying early spinal cord involvement. Their prognostic role in ADCC warrants further study.

Návaznosti

MUNI/A/1522/2024, interní kód MU

Název: Diagnostika komplikací a komorbidit neurologických onemocnění

Investor: Masarykova univerzita, Diagnostika komplikací a komorbidit neurologických onemocnění

NU22-04-00024, projekt VaV

Název: Kvantitativní zobrazovací MR parametry jako prediktory průběhu nemyelopatické degenerativní komprese krční míchy: longitudinální studie

Investor: Ministerstvo zdravotnictví ČR, Kvantitativní zobrazovací MR parametry jako prediktory průběhu nemyelopatické degenerativní komprese krční míchy: longitudinální studie, Podprogram 1 - standardní

Citovat

JOPPEKOVÁ, Ľubica; Adam BETÍK; Lucia BAKOŠOVÁ; Iva ŠROTOVÁ; Tomáš ROHAN; Miloš KEŘKOVSKÝ; Marek DOSTÁL; Jan ŠTULÍK; Martin NEMEC; Jan VALOSEK; Eva VLČKOVÁ a Josef BEDNAŘÍK. Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression. European Journal of Neurology. Hoboken: Wiley, 2025, roč. 32, č. 12, s. 1-13. ISSN 1351-5101. Dostupné z: https://doi.org/10.1111/ene.70454.

@article{2548308,
   author = {Joppeková, Ľubica and Betík, Adam and Bakošová, Lucia and Šrotová, Iva and Rohan, Tomáš and Keřkovský, Miloš and Dostál, Marek and Štulík, Jan and Nemec, Martin and Valosek, Jan and Vlčková, Eva and Bednařík, Josef},
   article_location = {Hoboken},
   article_number = {12},
   doi = {https://doi.org/10.1111/ene.70454},
   keywords = {electromyography; evoked potentials; magnetic resonance imaging; spinal cord compression; spinal cord diseases},
   language = {eng},
   issn = {1351-5101},
   journal = {European Journal of Neurology},
   title = {Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression},
   url = {https://onlinelibrary.wiley.com/doi/10.1111/ene.70454},
   volume = {32},
   year = {2025}
}

TY  - JOUR
ID  - 2548308
AU  - Joppeková, Ľubica - Betík, Adam - Bakošová, Lucia - Šrotová, Iva - Rohan, Tomáš - Keřkovský, Miloš - Dostál, Marek - Štulík, Jan - Nemec, Martin - Valosek, Jan - Vlčková, Eva - Bednařík, Josef
PY  - 2025
TI  - Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression
JF  - European Journal of Neurology
VL  - 32
IS  - 12
SP  - 1-13
EP  - 1-13
PB  - Wiley
SN  - 13515101
KW  - electromyography
KW  - evoked potentials
KW  - magnetic resonance imaging
KW  - spinal cord compression
KW  - spinal cord diseases
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ene.70454
N2  - Background Asymptomatic degenerative cervical cord compression (ADCC) represents a premyelopathic stage of degenerative cervical myelopathy (DCM), with high prevalence in older age and unclear management. Contact heat-evoked potentials (CHEPs) assess the integrity of the thermo-algesic somatosensory pathway and have shown the highest sensitivity among neurophysiological methods in detecting dysfunction in the centromedial and anterior spinal cord in DCM. Methods This cross-sectional cohort study evaluated the utility of upper extremity dermatomal C4, C6 and C8 CHEPs (dCHEPs) compared to standard neurophysiological methods-median and tibial nerves somatosensory evoked potentials (SEPs), upper and lower extremity motor evoked potentials (MEPs), and electromyography (EMG)-for detecting subclinical cervical cord dysfunction in ADCC. Two cohorts were included: 82 ADCC patients (mean age 53.7 +/- 9.8 years; 53 females) and 10 DCM patients (mean age 64.0 +/- 7.9 years; 4 females). All underwent bilateral dCHEPs (C4, C6, C8), SEPs, MEPs, and EMG (C5-C8 myotomes). Results dCHEPs abnormalities were found in 50% of ADCC patients, exceeding the rates for SEPs (32.1%), MEPs (21.8%), and EMG (13.9%). In 20.7%, dCHEPs were the only abnormal neurophysiological finding. In the DCM cohort, dCHEPs were abnormal in 80%, and were the only abnormality in 20%. In both groups, abnormalities were most frequent in the C8 dermatome. Conclusions dCHEPs demonstrated superior sensitivity in detecting cervical cord dysfunction, not only in DCM but also in ADCC. As a functional complement to MRI, they may aid in identifying early spinal cord involvement. Their prognostic role in ADCC warrants further study.
ER  -

JOPPEKOVÁ, Ľubica; Adam BETÍK; Lucia BAKOŠOVÁ; Iva ŠROTOVÁ; Tomáš ROHAN; Miloš KEŘKOVSKÝ; Marek DOSTÁL; Jan ŠTULÍK; Martin NEMEC; Jan VALOSEK; Eva VLČKOVÁ a Josef BEDNAŘÍK. Dermatomal Contact Heat Evoked Potentials for the Detection of Subclinical Cervical Spinal Cord Injury in Asymptomatic Degenerative Cervical Cord Compression. \textit{European Journal of Neurology}. Hoboken: Wiley, 2025, roč.~32, č.~12, s.~1-13. ISSN~1351-5101. Dostupné z: https://doi.org/10.1111/ene.70454.

Přehled o publikaci