The Timing of Diskectomy as a Predictor of Outcomes in Patients
With Lumbar Disk Herniation: A Cohort Study on Varying
Durations of Preoperative Symptoms

J 2026

The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms

SOLÁR, Peter; Dušan ONDÍRKO; Petra WESELÁ a Radim JANČÁLEK

Základní údaje

Originální název

The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms

Autoři

SOLÁR, Peter; Dušan ONDÍRKO; Petra WESELÁ a Radim JANČÁLEK

Vydání

NEUROSURGERY, PHILADELPHIA, LIPPINCOTT WILLIAMS & WILKINS, 2026, 0148-396X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30212 Surgery

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.900 v roce 2024

Označené pro přenos do RIV

Ano

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

lumbar disc herniation; discectomy timing; surgical outcomes; preoperative symptom duration; cohort study

Štítky

14110131, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 5. 2026 09:51, Mgr. Tereza Miškechová

Anotace

V originále

Background and objectives: Currently, the treatment of lumbar disk herniation (LDH) consists of conservative treatment followed by surgery when symptoms persist; however, the optimal timing of surgery to achieve the best clinical outcome is not clear. To evaluate the impact of durations of preoperative low back pain, disability, radicular leg pain, motor, and sensory deficit on postoperative outcomes in patients with LDH who underwent microdiskectomy. Methods: In our cohort study, we prospectively enrolled patients with different durations of preoperative LDH symptoms scheduled for microdiskectomy. The intensity and duration of radicular pain and disability were assessed using patient questionnaires. The motor deficit was classified based on the Medical Research Council scale. The sensory deficit was divided into present and absent. These parameters were assessed preoperatively and during postoperative 6-week, 6-, 12-, and 24-month follow-up visits. Results: In total, 1222 patients with LDH were enrolled. We observed that patients with LDH who underwent surgical intervention within 1 month after the onset of symptoms achieved more favorable outcomes compared with patients with longer duration of symptoms. Residual motor and sensory deficits 2 years after surgery were least common in patients with LDH-associated neurological symptoms lasting up to 1 month. Conclusion: Our results support the importance of timing surgery on the postoperative outcomes of patients with LDH. Surgery for LDH within 1 month of the onset of symptoms leads to a faster improvement in neurological deficit and more significant relief from radicular pain compared with the duration of the symptoms for more than 1 month.

Návaznosti

NW25J-10-00060, projekt VaV

Název: Role Cutibacterium acnes při rozvoji degenerativního onemocnění bederní meziobratlové ploténky a klinickém efektu mikrodiskektomie

Investor: Ministerstvo zdravotnictví ČR, Role Cutibacterium acnes při rozvoji degenerativního onemocnění bederní meziobratlové ploténky a klinickém efektu mikrodiskektomie, Podprogram 2 - juniorský

Citovat

SOLÁR, Peter; Dušan ONDÍRKO; Petra WESELÁ a Radim JANČÁLEK. The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms. NEUROSURGERY. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS, 2026, roč. 98, č. 5, s. 1051-1062. ISSN 0148-396X. Dostupné z: https://doi.org/10.1227/neu.0000000000003727.

@article{2548998,
   author = {Solár, Peter and Ondírko, Dušan and Weselá, Petra and Jančálek, Radim},
   article_location = {PHILADELPHIA},
   article_number = {5},
   doi = {https://doi.org/10.1227/neu.0000000000003727},
   keywords = {lumbar disc herniation; discectomy timing; surgical outcomes; preoperative symptom duration; cohort study},
   language = {eng},
   issn = {0148-396X},
   journal = {NEUROSURGERY},
   title = {The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms},
   url = {https://journals.lww.com/neurosurgery/fulltext/2026/05000/the_timing_of_diskectomy_as_a_predictor_of.10.aspx},
   volume = {98},
   year = {2026}
}

TY  - JOUR
ID  - 2548998
AU  - Solár, Peter - Ondírko, Dušan - Weselá, Petra - Jančálek, Radim
PY  - 2026
TI  - The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms
JF  - NEUROSURGERY
VL  - 98
IS  - 5
SP  - 1051-1062
EP  - 1051-1062
PB  - LIPPINCOTT WILLIAMS & WILKINS
SN  - 0148396X
KW  - lumbar disc herniation
KW  - discectomy timing
KW  - surgical outcomes
KW  - preoperative symptom duration
KW  - cohort study
UR  - https://journals.lww.com/neurosurgery/fulltext/2026/05000/the_timing_of_diskectomy_as_a_predictor_of.10.aspx
N2  - Background and objectives: Currently, the treatment of lumbar disk herniation (LDH) consists of conservative treatment followed by surgery when symptoms persist; however, the optimal timing of surgery to achieve the best clinical outcome is not clear. To evaluate the impact of durations of preoperative low back pain, disability, radicular leg pain, motor, and sensory deficit on postoperative outcomes in patients with LDH who underwent microdiskectomy. Methods: In our cohort study, we prospectively enrolled patients with different durations of preoperative LDH symptoms scheduled for microdiskectomy. The intensity and duration of radicular pain and disability were assessed using patient questionnaires. The motor deficit was classified based on the Medical Research Council scale. The sensory deficit was divided into present and absent. These parameters were assessed preoperatively and during postoperative 6-week, 6-, 12-, and 24-month follow-up visits. Results: In total, 1222 patients with LDH were enrolled. We observed that patients with LDH who underwent surgical intervention within 1 month after the onset of symptoms achieved more favorable outcomes compared with patients with longer duration of symptoms. Residual motor and sensory deficits 2 years after surgery were least common in patients with LDH-associated neurological symptoms lasting up to 1 month. Conclusion: Our results support the importance of timing surgery on the postoperative outcomes of patients with LDH. Surgery for LDH within 1 month of the onset of symptoms leads to a faster improvement in neurological deficit and more significant relief from radicular pain compared with the duration of the symptoms for more than 1 month.
ER  -

SOLÁR, Peter; Dušan ONDÍRKO; Petra WESELÁ a Radim JANČÁLEK. The Timing of Diskectomy as a Predictor of Outcomes in Patients With Lumbar Disk Herniation: A Cohort Study on Varying Durations of Preoperative Symptoms. \textit{NEUROSURGERY}. PHILADELPHIA: LIPPINCOTT WILLIAMS \&{} WILKINS, 2026, roč.~98, č.~5, s.~1051-1062. ISSN~0148-396X. Dostupné z: https://doi.org/10.1227/neu.0000000000003727.

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