New instrument for effective detection of a history of COPD
exacerbations, including usually unreported events

J 2025

New instrument for effective detection of a history of COPD exacerbations, including usually unreported events

ZATLOUKAL, Jaromir; Eva VOLAKOVA; Jana KOVACIKOVA; Martina KULIROVA; Miroslav MARUSCAK et al.

Základní údaje

Originální název

New instrument for effective detection of a history of COPD exacerbations, including usually unreported events

Autoři

ZATLOUKAL, Jaromir; Eva VOLAKOVA; Jana KOVACIKOVA; Martina KULIROVA; Miroslav MARUSCAK; Blanka HYTYCHOVA a Vladimir KOBLIZEK

Vydání

Frontiers in Medicine, LAUSANNE, FRONTIERS MEDIA SA, 2025, 2296-858X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30230 Other clinical medicine subjects

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.000 v roce 2024

Organizační jednotka

CZECRIN IV

DOI

https://doi.org/10.3389/fmed.2025.1630338

UT WoS

001586753800001

Klíčová slova česky

obstructive lung disease; structured checklist; questionnaire; flare-up; disease history; dyspnea; cough

Klíčová slova anglicky

obstructive lung disease; structured checklist; questionnaire; flare-up; disease history; dyspnea; cough

Štítky

Excelence Science, FN HK, RIV, user, článek v časopise

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 1. 2026 09:56, Bc. Hana Vladíková, BBA

Anotace

V originále

Background: COPD exacerbations are important events for disease management. The incidence of exacerbations impacts prognosis, guides treatment, and predicts future exacerbations. Despite their importance, exacerbations are often underdiagnosed and underreported. The aim of our study was to test and evaluate the effectiveness of a structured checklist for detecting past exacerbations that we developed and that would be suitable for routine clinical practice. Methods: 350 patients with COPD and FEV1 < 80% of the predicted value were enrolled in 35 centers. Each patient completed a structured checklist and underwent an interview with the physician. The number of exacerbations, their symptoms and duration, and the treatments were evaluated. Clinical data on exacerbations in the previous 12 months were retrieved from the patient's medical records and analyzed retrospectively. The data obtained using the structured checklist were compared with the data from the interviews and medical records. Results: Compared to the patient-physician interview, the structured checklist detected more exacerbations since the previous visit (p = 0.025). The difference was significant also for severe exacerbations (p = 0.003). In patients reporting only one event, the structured checklist was more sensitive in detecting mild events than the interview (p < 0.001). The structured checklist detected mild exacerbations in 10 patients in whom the interview detected none. Compared to the number of exacerbations in the medical records, the structured checklist detected more than twice as many events. The mean duration of an exacerbation was 9.7 days, and the most prominent symptoms were dyspnea and productive cough. Conclusion: Proposed structured checklist improved the detection of past exacerbations, including usually unreported events. Moreover, the structured checklist allows the severity and other clinical characteristics of past exacerbations to be specified and used to direct further COPD therapy.

Návaznosti

90249, velká výzkumná infrastruktura

Název: CZECRIN IV

Citovat

ZATLOUKAL, Jaromir; Eva VOLAKOVA; Jana KOVACIKOVA; Martina KULIROVA; Miroslav MARUSCAK; Blanka HYTYCHOVA a Vladimir KOBLIZEK. New instrument for effective detection of a history of COPD exacerbations, including usually unreported events. Frontiers in Medicine. LAUSANNE: FRONTIERS MEDIA SA, 2025, roč. 12, NA, s. 1-10. ISSN 2296-858X. Dostupné z: https://doi.org/10.3389/fmed.2025.1630338.

@article{2549173,
   author = {Zatloukal, Jaromir and Volakova, Eva and Kovacikova, Jana and Kulirova, Martina and Maruscak, Miroslav and Hytychova, Blanka and Koblizek, Vladimir},
   article_location = {LAUSANNE},
   article_number = {NA},
   doi = {https://doi.org/10.3389/fmed.2025.1630338},
   keywords = {obstructive lung disease; structured checklist; questionnaire; flare-up; disease history; dyspnea; cough},
   language = {eng},
   issn = {2296-858X},
   journal = {Frontiers in Medicine},
   title = {New instrument for effective detection of a history of COPD exacerbations, including usually unreported events},
   url = {https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1630338/full},
   volume = {12},
   year = {2025}
}

TY  - JOUR
ID  - 2549173
AU  - Zatloukal, Jaromir - Volakova, Eva - Kovacikova, Jana - Kulirova, Martina - Maruscak, Miroslav - Hytychova, Blanka - Koblizek, Vladimir
PY  - 2025
TI  - New instrument for effective detection of a history of COPD exacerbations, including usually unreported events
JF  - Frontiers in Medicine
VL  - 12
IS  - NA
SP  - 1-10
EP  - 1-10
PB  - FRONTIERS MEDIA SA
SN  - 2296858X
KW  - obstructive lung disease
KW  - structured checklist
KW  - questionnaire
KW  - flare-up
KW  - disease history
KW  - dyspnea
KW  - cough
UR  - https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1630338/full
N2  - Background: COPD exacerbations are important events for disease management. The incidence of exacerbations impacts prognosis, guides treatment, and predicts future exacerbations. Despite their importance, exacerbations are often underdiagnosed and underreported. The aim of our study was to test and evaluate the effectiveness of a structured checklist for detecting past exacerbations that we developed and that would be suitable for routine clinical practice. Methods: 350 patients with COPD and FEV1 < 80% of the predicted value were enrolled in 35 centers. Each patient completed a structured checklist and underwent an interview with the physician. The number of exacerbations, their symptoms and duration, and the treatments were evaluated. Clinical data on exacerbations in the previous 12 months were retrieved from the patient's medical records and analyzed retrospectively. The data obtained using the structured checklist were compared with the data from the interviews and medical records. Results: Compared to the patient-physician interview, the structured checklist detected more exacerbations since the previous visit (p = 0.025). The difference was significant also for severe exacerbations (p = 0.003). In patients reporting only one event, the structured checklist was more sensitive in detecting mild events than the interview (p < 0.001). The structured checklist detected mild exacerbations in 10 patients in whom the interview detected none. Compared to the number of exacerbations in the medical records, the structured checklist detected more than twice as many events. The mean duration of an exacerbation was 9.7 days, and the most prominent symptoms were dyspnea and productive cough. Conclusion: Proposed structured checklist improved the detection of past exacerbations, including usually unreported events. Moreover, the structured checklist allows the severity and other clinical characteristics of past exacerbations to be specified and used to direct further COPD therapy.
ER  -

ZATLOUKAL, Jaromir; Eva VOLAKOVA; Jana KOVACIKOVA; Martina KULIROVA; Miroslav MARUSCAK; Blanka HYTYCHOVA a Vladimir KOBLIZEK. New instrument for effective detection of a history of COPD exacerbations, including usually unreported events. \textit{Frontiers in Medicine}. LAUSANNE: FRONTIERS MEDIA SA, 2025, roč.~12, NA, s.~1-10. ISSN~2296-858X. Dostupné z: https://doi.org/10.3389/fmed.2025.1630338.

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