Response to Letter to Editor by A. Derbalah et al.: the role of
automation in enhancing reproducibility and interoperability of
PBPK models

J 2025

Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models

DOMINGUEZ ROMERO, Elena; Stanislav MAZURENKO; Martin SCHERINGER; Vitor A. P. Martins DOS SANTOS; Chris T. EVELO et al.

Základní údaje

Originální název

Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models

Autoři

DOMINGUEZ ROMERO, Elena; Stanislav MAZURENKO; Martin SCHERINGER; Vitor A. P. Martins DOS SANTOS; Chris T. EVELO; Mihail ANTON; John M. HANCOCK; Anze ZUPANIC a Maria SUAREZ-DIEZ

Vydání

BRIEFINGS IN BIOINFORMATICS, OXFORD, OXFORD UNIV PRESS, 2025, 1467-5463

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10609 Biochemical research methods

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.700 v roce 2024

Označené pro přenos do RIV

Ano

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

reproducibility; PBPK models; standardization; automation

Štítky

143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 1. 2026 09:22, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

This text discusses automation in physiologically based pharmacokinetic (PBPK) modeling, emphasizing its benefits for building complex models efficiently and reproducibly. Manual scripting remains valuable for smaller models for teaching and conceptual understanding. The authors highlight the need for standardization and open collaboration through ELIXIR to advance automated PBPK model development.

Citovat

DOMINGUEZ ROMERO, Elena; Stanislav MAZURENKO; Martin SCHERINGER; Vitor A. P. Martins DOS SANTOS; Chris T. EVELO; Mihail ANTON; John M. HANCOCK; Anze ZUPANIC a Maria SUAREZ-DIEZ. Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models. BRIEFINGS IN BIOINFORMATICS. OXFORD: OXFORD UNIV PRESS, 2025, roč. 26, č. 1, s. 1-2. ISSN 1467-5463. Dostupné z: https://doi.org/10.1093/bib/bbaf060.

@article{2550362,
   author = {Dominguez Romero, Elena and Mazurenko, Stanislav and Scheringer, Martin and dos Santos, Vitor A. P. Martins and Evelo, Chris T. and Anton, Mihail and Hancock, John M. and Zupanic, Anze and SuarezandDiez, Maria},
   article_location = {OXFORD},
   article_number = {1},
   doi = {https://doi.org/10.1093/bib/bbaf060},
   keywords = {reproducibility; PBPK models; standardization; automation},
   language = {eng},
   issn = {1467-5463},
   journal = {BRIEFINGS IN BIOINFORMATICS},
   title = {Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models},
   url = {https://academic.oup.com/bib/article/26/1/bbaf060/8006249},
   volume = {26},
   year = {2025}
}

TY  - JOUR
ID  - 2550362
AU  - Dominguez Romero, Elena - Mazurenko, Stanislav - Scheringer, Martin - dos Santos, Vitor A. P. Martins - Evelo, Chris T. - Anton, Mihail - Hancock, John M. - Zupanic, Anze - Suarez-Diez, Maria
PY  - 2025
TI  - Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models
JF  - BRIEFINGS IN BIOINFORMATICS
VL  - 26
IS  - 1
SP  - 1-2
EP  - 1-2
PB  - OXFORD UNIV PRESS
SN  - 14675463
KW  - reproducibility
KW  - PBPK models
KW  - standardization
KW  - automation
UR  - https://academic.oup.com/bib/article/26/1/bbaf060/8006249
N2  - This text discusses automation in physiologically based pharmacokinetic (PBPK) modeling, emphasizing its benefits for building complex models efficiently and reproducibly. Manual scripting remains valuable for smaller models for teaching and conceptual understanding. The authors highlight the need for standardization and open collaboration through ELIXIR to advance automated PBPK model development.
ER  -

DOMINGUEZ ROMERO, Elena; Stanislav MAZURENKO; Martin SCHERINGER; Vitor A. P. Martins DOS SANTOS; Chris T. EVELO; Mihail ANTON; John M. HANCOCK; Anze ZUPANIC a Maria SUAREZ-DIEZ. Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models. \textit{BRIEFINGS IN BIOINFORMATICS}. OXFORD: OXFORD UNIV PRESS, 2025, roč.~26, č.~1, s.~1-2. ISSN~1467-5463. Dostupné z: https://doi.org/10.1093/bib/bbaf060.

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