SSI and their Treatment: A Comprehensive Approach

p 2025

SSI and their Treatment: A Comprehensive Approach

VEVERKOVÁ, Lenka a Petr DOLEŽAL

Základní údaje

Originální název

SSI and their Treatment: A Comprehensive Approach

Autoři

VEVERKOVÁ, Lenka a Petr DOLEŽAL

Vydání

LINK for Wound Healing Congress 2025 Berlin Germany, 2025

Další údaje

Jazyk

angličtina

Typ výsledku

Vyžádané přednášky

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

SSI NPWT

Změněno: 17. 3. 2026 14:46, Mgr. Tereza Miškechová

Anotace

V originále

Introduction Surgical site infections (SSI) are a significant complication in oncological patients due to immunosuppression, malnutrition, and the effects of cancer treatments such as chemotherapy and radiotherapy. These factors impair wound healing, increasing the risk of infections. Oncological patients often undergo major surgeries, which further complicates recovery. The study aimed to assess the incidence of SSI in oncological patients and identify associated risk factors. Methods A retrospective analysis was conducted using data from 38,596 hospitalizations at the First Surgical Clinic of FN USA in Brno between 2013 and 2024. Among these, 2,425 patients underwent surgery for oncological diagnoses under general anesthesia. SSI cases were identified and analyzed. Data was extracted from the clinical information system NISstat, and statistical analysis was performed using R software. Hypothesis testing was carried out using Welch's t-test and Pearson’s Chi-squared test. Results SSI occurred in 201 out of 2,425 oncological surgeries (8.3%). Statistical analysis revealed that an oncological diagnosis was a significant risk factor for the development of SSI (p < 0.001). The median length of hospitalization for patients with SSI was 7 days, while the presence of an oncological diagnosis did not significantly impact hospitalization duration. Negative pressure wound therapy (NPWT) was used in 137 patients and was associated with shorter treatment and hospitalization durations. Discussion/Conclusion Oncological patients are at higher risk for SSI, and their treatment requires a comprehensive approach, including advanced wound management methods like NPWT. Early detection and appropriate intervention are essential to improving patient outcomes and minimizing healthcare costs

Návaznosti

MUNI/A/1692/2024, interní kód MU

Název: Ovlivnění strategie chirurgické léčby u komplikovaných operací II

Investor: Masarykova univerzita, Ovlivnění strategie chirurgické léčby u komplikovaných operací II

Citovat

VEVERKOVÁ, Lenka a Petr DOLEŽAL. SSI and their Treatment: A Comprehensive Approach. In LINK for Wound Healing Congress 2025 Berlin Germany. 2025.

@misc{2551718,
   author = {Veverková, Lenka and Doležal, Petr},
   booktitle = {LINK for Wound Healing Congress 2025 Berlin Germany},
   keywords = {SSI NPWT},
   language = {eng},
   title = {SSI and their Treatment: A Comprehensive Approach},
   url = {https://www.linkforwoundhealing.info/en/events/2025/link-for-wound-healing-congress-2025},
   year = {2025}
}

TY  - SLIDE
ID  - 2551718
AU  - Veverková, Lenka - Doležal, Petr
PY  - 2025
TI  - SSI and their Treatment: A Comprehensive Approach
KW  - SSI NPWT
UR  - https://www.linkforwoundhealing.info/en/events/2025/link-for-wound-healing-congress-2025
N2  - Introduction Surgical site infections (SSI) are a significant complication in oncological patients due to immunosuppression, malnutrition, and the effects of cancer treatments such as chemotherapy and radiotherapy. These factors impair wound healing, increasing the risk of infections. Oncological patients often undergo major surgeries, which further complicates recovery. The study aimed to assess the incidence of SSI in oncological patients and identify associated risk factors. Methods A retrospective analysis was conducted using data from 38,596 hospitalizations at the First Surgical Clinic of FN USA in Brno between 2013 and 2024. Among these, 2,425 patients underwent surgery for oncological diagnoses under general anesthesia. SSI cases were identified and analyzed. Data was extracted from the clinical information system NISstat, and statistical analysis was performed using R software. Hypothesis testing was carried out using Welch's t-test and Pearson’s Chi-squared test. Results SSI occurred in 201 out of 2,425 oncological surgeries (8.3%). Statistical analysis revealed that an oncological diagnosis was a significant risk factor for the development of SSI (p < 0.001). The median length of hospitalization for patients with SSI was 7 days, while the presence of an oncological diagnosis did not significantly impact hospitalization duration. Negative pressure wound therapy (NPWT) was used in 137 patients and was associated with shorter treatment and hospitalization durations. Discussion/Conclusion Oncological patients are at higher risk for SSI, and their treatment requires a comprehensive approach, including advanced wound management methods like NPWT. Early detection and appropriate intervention are essential to improving patient outcomes and minimizing healthcare costs
ER  -

VEVERKOVÁ, Lenka a Petr DOLEŽAL. SSI and their Treatment: A Comprehensive Approach. In \textit{LINK for Wound Healing Congress 2025 Berlin Germany}. 2025.

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