Late posttonsillectomy haemorrhage, differences in unilateral
versus bilateral tonsillectomy, a retrospective epidemiological
multicentric study

J 2025

Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study

VODICKA, Jan; Viktor CHROBOK; Martin CHOVANEC; Milan URÍK; Břetislav GÁL et al.

Základní údaje

Originální název

Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study

Autoři

Vydání

Nature Scientific Reports, Berlin, NATURE RESEARCH, 2025, 2045-2322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30206 Otorhinolaryngology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.900 v roce 2024

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/25:00143813

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Tonsillectomy; Haemorrhage; Late post-tonsillectomy haemorrhage

Štítky

14110126, 14110319, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 2. 2026 09:22, Mgr. Tereza Miškechová

Anotace

V originále

Tonsillectomy (TE) is one of the most performed head and neck surgeries. Patients range from children to seniors, and there is a wide range of indications and various complications related to TE. The most feared complication is post-tonsillectomy haemorrhage (PTH). Multicentric retrospective study, conducted between 2014 and 2018, includes data from 8166 patients who underwent TE. Among these patients, 3889 were men (47.62%) and 4277 were women (52.28%), with a mean age of 29.06 years. For this study, we analysed a total of 14,030 unilateral tonsillectomies (resected tonsils), of which 2,302 were performed primarily as unilateral surgeries, while 11,728 were part of bilateral procedures. Late post-tonsillectomy haemorrhage (LPTH) was significantly associated with the type of surgery performed (unilateral versus bilateral procedure; p < 0.0001). In the unilateral group, bleeding occurred in 217 cases (9.43%), while in the bilateral group, it was noted in 1062 cases (18.11%). When analysing the total sample (14030 unilateral tonsillectomies), the incidence of LPTH was found to be 9.12%. The occurrence of bleeding in our sample was influenced by several factors, including hospital choice, age, and gender (p < 0.0001). Additionally, the use of anticoagulants was associated with bleeding (p = 0.0449), as was antiplatelet medication (p = 0.0160). However, factors such as the spectrum of indications, surgical technique, surgeon experience, and the use of electrocoagulation during surgery did not impact LPTH. The severity of bleeding was linked to the use of anticoagulants (p = 0.0002) and antiplatelet medication (p = 0.0404). Our study highlighted the importance of methodology when studying LPTH as the outcome of unilateral and bilateral TE procedures. LPTH occurrence was most influenced by the choice of hospital and the patient's age and gender. The severity of bleeding was affected by the use of anticoagulants and antiplatelet agents. The manner in which LPTH was treated did not affect the likelihood of LPTH recurrence.

Citovat

VODICKA, Jan; Viktor CHROBOK; Martin CHOVANEC; Milan URÍK; Břetislav GÁL; Richard SALZMAN; Rami KATRA; Petr SKOPEK; Jan KOLIN; Zdenek KNIZEK; Hana DOLEZALOVA; Libor SYCHRA; Patrik BURSA; Lenka JETMAROVA; Silvia BERKOVA; Pavel STREJCEK; Josef HAJEK; Zdenek KUCERA; Jakub SYROVATKA; Tomas KOSTLIVY a David SLOUKA. Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study. Nature Scientific Reports. Berlin: NATURE RESEARCH, 2025, roč. 15, č. 1, s. 1-16. ISSN 2045-2322. Dostupné z: https://doi.org/10.1038/s41598-025-28189-x.

@article{2557105,
   author = {Vodicka, Jan and Chrobok, Viktor and Chovanec, Martin and Urík, Milan and Gál, Břetislav and Salzman, Richard and Katra, Rami and Skopek, Petr and Kolin, Jan and Knizek, Zdenek and Dolezalova, Hana and Sychra, Libor and Bursa, Patrik and Jetmarova, Lenka and Berkova, Silvia and Strejcek, Pavel and Hajek, Josef and Kucera, Zdenek and Syrovatka, Jakub and Kostlivy, Tomas and Slouka, David},
   article_location = {Berlin},
   article_number = {1},
   doi = {https://doi.org/10.1038/s41598-025-28189-x},
   keywords = {Tonsillectomy; Haemorrhage; Late post-tonsillectomy haemorrhage},
   language = {eng},
   issn = {2045-2322},
   journal = {Nature Scientific Reports},
   title = {Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study},
   url = {https://www.nature.com/articles/s41598-025-28189-x},
   volume = {15},
   year = {2025}
}

TY  - JOUR
ID  - 2557105
AU  - Vodicka, Jan - Chrobok, Viktor - Chovanec, Martin - Urík, Milan - Gál, Břetislav - Salzman, Richard - Katra, Rami - Skopek, Petr - Kolin, Jan - Knizek, Zdenek - Dolezalova, Hana - Sychra, Libor - Bursa, Patrik - Jetmarova, Lenka - Berkova, Silvia - Strejcek, Pavel - Hajek, Josef - Kucera, Zdenek - Syrovatka, Jakub - Kostlivy, Tomas - Slouka, David
PY  - 2025
TI  - Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study
JF  - Nature Scientific Reports
VL  - 15
IS  - 1
SP  - 1-16
EP  - 1-16
PB  - NATURE RESEARCH
SN  - 20452322
KW  - Tonsillectomy
KW  - Haemorrhage
KW  - Late post-tonsillectomy haemorrhage
UR  - https://www.nature.com/articles/s41598-025-28189-x
N2  - Tonsillectomy (TE) is one of the most performed head and neck surgeries. Patients range from children to seniors, and there is a wide range of indications and various complications related to TE. The most feared complication is post-tonsillectomy haemorrhage (PTH). Multicentric retrospective study, conducted between 2014 and 2018, includes data from 8166 patients who underwent TE. Among these patients, 3889 were men (47.62%) and 4277 were women (52.28%), with a mean age of 29.06 years. For this study, we analysed a total of 14,030 unilateral tonsillectomies (resected tonsils), of which 2,302 were performed primarily as unilateral surgeries, while 11,728 were part of bilateral procedures. Late post-tonsillectomy haemorrhage (LPTH) was significantly associated with the type of surgery performed (unilateral versus bilateral procedure; p < 0.0001). In the unilateral group, bleeding occurred in 217 cases (9.43%), while in the bilateral group, it was noted in 1062 cases (18.11%). When analysing the total sample (14030 unilateral tonsillectomies), the incidence of LPTH was found to be 9.12%. The occurrence of bleeding in our sample was influenced by several factors, including hospital choice, age, and gender (p < 0.0001). Additionally, the use of anticoagulants was associated with bleeding (p = 0.0449), as was antiplatelet medication (p = 0.0160). However, factors such as the spectrum of indications, surgical technique, surgeon experience, and the use of electrocoagulation during surgery did not impact LPTH. The severity of bleeding was linked to the use of anticoagulants (p = 0.0002) and antiplatelet medication (p = 0.0404). Our study highlighted the importance of methodology when studying LPTH as the outcome of unilateral and bilateral TE procedures. LPTH occurrence was most influenced by the choice of hospital and the patient's age and gender. The severity of bleeding was affected by the use of anticoagulants and antiplatelet agents. The manner in which LPTH was treated did not affect the likelihood of LPTH recurrence.
ER  -

VODICKA, Jan; Viktor CHROBOK; Martin CHOVANEC; Milan URÍK; Břetislav GÁL; Richard SALZMAN; Rami KATRA; Petr SKOPEK; Jan KOLIN; Zdenek KNIZEK; Hana DOLEZALOVA; Libor SYCHRA; Patrik BURSA; Lenka JETMAROVA; Silvia BERKOVA; Pavel STREJCEK; Josef HAJEK; Zdenek KUCERA; Jakub SYROVATKA; Tomas KOSTLIVY a David SLOUKA. Late posttonsillectomy haemorrhage, differences in unilateral versus bilateral tonsillectomy, a retrospective epidemiological multicentric study. \textit{Nature Scientific Reports}. Berlin: NATURE RESEARCH, 2025, roč.~15, č.~1, s.~1-16. ISSN~2045-2322. Dostupné z: https://doi.org/10.1038/s41598-025-28189-x.

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