Compact Monocular Video-Ophthalmoscope to Measure Retinal
Reflectance Changes to Flicker Light Stimuli

J 2025

Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

KOLAR, Radim; Tomas VICAR; Jiri CHMELIK; Roman JAKUBICEK; Jan ODSTRCILIK et al.

Základní údaje

Originální název

Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

Autoři

KOLAR, Radim; Tomas VICAR; Jiri CHMELIK; Roman JAKUBICEK; Jan ODSTRCILIK; Michal NOHEL; Karolína SKORKOVSKÁ a Ralf P TORNOW

Vydání

Journal of biophotonics, Weinheim, Wiley-VCH, 2025, 1864-063X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30207 Ophthalmology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.300 v roce 2024

Označené pro přenos do RIV

Ano

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

blood volume; fundus reflectance; light flickering; neurovascular coupling; optic nerve head; video-ophthalmoscopy

Štítky

14110615, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 3. 2026 08:25, Mgr. Tereza Miškechová

Anotace

V originále

This paper describes a compact video-ophthalmoscope (VO) designed for capturing retinal video sequences of the optic nerve head (ONH) under flicker light stimulation. The device uses an OLED display and a fiber optic-coupled LED light source, enabling high-frame-rate video at low illumination intensity (12 mu W/cm2). Retinal responses were recorded in 10 healthy subjects during flicker light exposure with a pupil irradiance of 2 mu W/cm2. Following 20 s of stimulation, all subjects displayed changes in retinal reflectance and pulsation attenuation, linked to blood flow and volume variations. These findings suggest that increased blood volume leads to decreased retinal reflectance. Temporal analysis confirmed the ability to capture flicker-induced retinal reflectance changes, indicating its potential for spatial and temporal analysis. Overall, this device offers a portable approach for investigating dynamic retinal responses to light stimuli, which can aid the diagnosis of retinal diseases like diabetic retinopathy, glaucoma, or neurodegenerative diseases affecting retinal blood circulation.

Citovat

KOLAR, Radim; Tomas VICAR; Jiri CHMELIK; Roman JAKUBICEK; Jan ODSTRCILIK; Michal NOHEL; Karolína SKORKOVSKÁ a Ralf P TORNOW. Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli. Journal of biophotonics. Weinheim: Wiley-VCH, 2025, roč. 18, č. 6, s. 1-10. ISSN 1864-063X. Dostupné z: https://doi.org/10.1002/jbio.202400494.

@article{2558419,
   author = {Kolar, Radim and Vicar, Tomas and Chmelik, Jiri and Jakubicek, Roman and Odstrcilik, Jan and Nohel, Michal and Skorkovská, Karolína and Tornow, Ralf P},
   article_location = {Weinheim},
   article_number = {6},
   doi = {https://doi.org/10.1002/jbio.202400494},
   keywords = {blood volume; fundus reflectance; light flickering; neurovascular coupling; optic nerve head; video-ophthalmoscopy},
   language = {eng},
   issn = {1864-063X},
   journal = {Journal of biophotonics},
   title = {Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli},
   url = {https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494},
   volume = {18},
   year = {2025}
}

TY  - JOUR
ID  - 2558419
AU  - Kolar, Radim - Vicar, Tomas - Chmelik, Jiri - Jakubicek, Roman - Odstrcilik, Jan - Nohel, Michal - Skorkovská, Karolína - Tornow, Ralf P
PY  - 2025
TI  - Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli
JF  - Journal of biophotonics
VL  - 18
IS  - 6
SP  - 1-10
EP  - 1-10
PB  - Wiley-VCH
SN  - 1864063X
KW  - blood volume
KW  - fundus reflectance
KW  - light flickering
KW  - neurovascular coupling
KW  - optic nerve head
KW  - video-ophthalmoscopy
UR  - https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494
N2  - This paper describes a compact video-ophthalmoscope (VO) designed for capturing retinal video sequences of the optic nerve head (ONH) under flicker light stimulation. The device uses an OLED display and a fiber optic-coupled LED light source, enabling high-frame-rate video at low illumination intensity (12 mu W/cm2). Retinal responses were recorded in 10 healthy subjects during flicker light exposure with a pupil irradiance of 2 mu W/cm2. Following 20 s of stimulation, all subjects displayed changes in retinal reflectance and pulsation attenuation, linked to blood flow and volume variations. These findings suggest that increased blood volume leads to decreased retinal reflectance. Temporal analysis confirmed the ability to capture flicker-induced retinal reflectance changes, indicating its potential for spatial and temporal analysis. Overall, this device offers a portable approach for investigating dynamic retinal responses to light stimuli, which can aid the diagnosis of retinal diseases like diabetic retinopathy, glaucoma, or neurodegenerative diseases affecting retinal blood circulation.
ER  -

KOLAR, Radim; Tomas VICAR; Jiri CHMELIK; Roman JAKUBICEK; Jan ODSTRCILIK; Michal NOHEL; Karolína SKORKOVSKÁ a Ralf P TORNOW. Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli. \textit{Journal of biophotonics}. Weinheim: Wiley-VCH, 2025, roč.~18, č.~6, s.~1-10. ISSN~1864-063X. Dostupné z: https://doi.org/10.1002/jbio.202400494.

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