Traditional Human Populations and Nonhuman Primates Show
Parallel Gut Microbiome Adaptations to Analogous Ecological
Conditions

J 2020

Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions

SHARMA, Ashok K.; Klara PETRZELKOVA; Barbora PAFČO; Carolyn A. Jost ROBINSON; Terence FUH et al.

Základní údaje

Originální název

Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions

Autoři

Vydání

MSYSTEMS, WASHINGTON, AMER SOC MICROBIOLOGY, 2020

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10606 Microbiology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

gut microbiome; metagenomics; gorillas; traditional agriculturalists; hunter-gatherers

Štítky

RIV ne

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 3. 2026 14:51, Mgr. Lucie Jarošová, DiS.

Anotace

V originále

Compared with urban-industrial populations, small-scale human communities worldwide share a significant number of gut microbiome traits with nonhuman primates. This overlap is thought to be driven by analogous dietary triggers; however, the ecological and functional bases of this similarity are not fully understood. To start addressing this issue, fecal metagenomes of BaAka hunter-gatherers and traditional Bantu agriculturalists from the Central African Republic were profiled and compared with those of a sympatric western lowland gorilla group (Gorilla gorilla gorilla) across two seasons of variable dietary intake. Results show that gorilla gut microbiomes shared similar functional traits with each human group, depending on seasonal dietary behavior. Specifically, parallel microbiome traits were observed between hunter-gatherers and gorillas when the latter consumed more structural polysaccharides during dry seasons, while small-scale agriculturalist and gorilla microbiomes showed significant functional overlap when gorillas consumed more seasonal ripe fruit during wet seasons. Notably, dominance of microbial transporters, transduction systems, and gut xenobiotic metabolism was observed in association with traditional agriculture and energy-dense diets in gorillas at the expense of a functional microbiome repertoire capable of metabolizing more complex polysaccharides. Differential abundance of bacterial taxa that typically distinguish traditional from industrialized human populations (e.g., Prevotella spp.) was also recapitulated in the human and gorilla groups studied, possibly reflecting the degree of polysaccharide complexity included in each group's dietary niche. These results show conserved functional gut microbiome adaptations to analogous diets in small-scale human populations and nonhuman primates, highlighting the role of plant dietary polysaccharides and diverse environmental exposures in this convergence.

Citovat

SHARMA, Ashok K.; Klara PETRZELKOVA; Barbora PAFČO; Carolyn A. Jost ROBINSON; Terence FUH; Brenda A. WILSON; Rebecca M. STUMPF; Manolito G. TORRALBA; Ran BLEKHMAN; Bryan WHITE; Karen E. NELSON; Steven R. LEIGH a Andres GOMEZ. Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions. Online. MSYSTEMS. WASHINGTON: AMER SOC MICROBIOLOGY, 2020, roč. 5, č. 6, s. 1-18. Dostupné z: https://doi.org/10.1128/mSystems.00815-20.

@article{2558551,
   author = {Sharma, Ashok K. and Petrzelkova, Klara and Pafčo, Barbora and Robinson, Carolyn A. Jost and Fuh, Terence and Wilson, Brenda A. and Stumpf, Rebecca M. and Torralba, Manolito G. and Blekhman, Ran and White, Bryan and Nelson, Karen E. and Leigh, Steven R. and Gomez, Andres},
   article_location = {WASHINGTON},
   article_number = {6},
   doi = {https://doi.org/10.1128/mSystems.00815-20},
   keywords = {gut microbiome; metagenomics; gorillas; traditional agriculturalists; hunter-gatherers},
   language = {eng},
   journal = {MSYSTEMS},
   title = {Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions},
   url = {http://dx.doi.org/10.1128/mSystems.00815-20},
   volume = {5},
   year = {2020}
}

TY  - JOUR
ID  - 2558551
AU  - Sharma, Ashok K. - Petrzelkova, Klara - Pafčo, Barbora - Robinson, Carolyn A. Jost - Fuh, Terence - Wilson, Brenda A. - Stumpf, Rebecca M. - Torralba, Manolito G. - Blekhman, Ran - White, Bryan - Nelson, Karen E. - Leigh, Steven R. - Gomez, Andres
PY  - 2020
TI  - Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions
JF  - MSYSTEMS
VL  - 5
IS  - 6
SP  - 1-18
EP  - 1-18
PB  - AMER SOC MICROBIOLOGY
KW  - gut microbiome
KW  - metagenomics
KW  - gorillas
KW  - traditional agriculturalists
KW  - hunter-gatherers
UR  - http://dx.doi.org/10.1128/mSystems.00815-20
N2  - Compared with urban-industrial populations, small-scale human communities worldwide share a significant number of gut microbiome traits with nonhuman primates. This overlap is thought to be driven by analogous dietary triggers; however, the ecological and functional bases of this similarity are not fully understood. To start addressing this issue, fecal metagenomes of BaAka hunter-gatherers and traditional Bantu agriculturalists from the Central African Republic were profiled and compared with those of a sympatric western lowland gorilla group (Gorilla gorilla gorilla) across two seasons of variable dietary intake. Results show that gorilla gut microbiomes shared similar functional traits with each human group, depending on seasonal dietary behavior. Specifically, parallel microbiome traits were observed between hunter-gatherers and gorillas when the latter consumed more structural polysaccharides during dry seasons, while small-scale agriculturalist and gorilla microbiomes showed significant functional overlap when gorillas consumed more seasonal ripe fruit during wet seasons. Notably, dominance of microbial transporters, transduction systems, and gut xenobiotic metabolism was observed in association with traditional agriculture and energy-dense diets in gorillas at the expense of a functional microbiome repertoire capable of metabolizing more complex polysaccharides. Differential abundance of bacterial taxa that typically distinguish traditional from industrialized human populations (e.g., Prevotella spp.) was also recapitulated in the human and gorilla groups studied, possibly reflecting the degree of polysaccharide complexity included in each group's dietary niche. These results show conserved functional gut microbiome adaptations to analogous diets in small-scale human populations and nonhuman primates, highlighting the role of plant dietary polysaccharides and diverse environmental exposures in this convergence.
ER  -

SHARMA, Ashok K.; Klara PETRZELKOVA; Barbora PAFČO; Carolyn A. Jost ROBINSON; Terence FUH; Brenda A. WILSON; Rebecca M. STUMPF; Manolito G. TORRALBA; Ran BLEKHMAN; Bryan WHITE; Karen E. NELSON; Steven R. LEIGH a Andres GOMEZ. Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions. Online. \textit{MSYSTEMS}. WASHINGTON: AMER SOC MICROBIOLOGY, 2020, roč.~5, č.~6, s.~1-18. Dostupné z: https://doi.org/10.1128/mSystems.00815-20.

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