Restoration of lamellar structures in adult rat Pacinian
corpuscles following their simultaneous freezing injury and
denervation

J 2000

Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation

DUBOVÝ, Petr

Základní údaje

Originální název

Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation

Název česky

Obnova lamel vnitřního sloupce Paciniho tělísek po jejich mrazovém poškození a denervaci

Autoři

DUBOVÝ, Petr

Vydání

Anatomy and Embryology, Heidelberg, Springer-Verlag, 2000, 0340-2061

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.851

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/00:00002374

Organizační jednotka

Lékařská fakulta

UT WoS

000089074400006

Klíčová slova anglicky

inner core; Schwann cells

Štítky

inner core, Schwann cells

Změněno: 17. 6. 2009 11:41, prof. RNDr. Petr Dubový, CSc.

Anotace

ORIG CZ

V originále

The capsule and inner core are multilamellar auxiliary structures enveloping the axon terminal of the Pacinian corpuscle. The freezing injury of the rat interosseal Pacinian corpuscles induced the destruction of all cellular components while the extracellular matrix including the basal laminae survive the treatment. Simultaneous denervation and the freezing treatment of the Pacinian corpuscles discovered an ability of the basal lamina and other components of the extracellular matrix to stimulate a differentiation of migrated Schwann cells and fibroblasts into multilamellar auxiliary structures. The restoration of inner core and capsule in the Pacinian corpuscles was independent of the presence of sensory axon terminals. The restored lamellar structures of Pacinian corpuscles in long-term surviving rat (4 to 8 months) displayed atrophic changes. The results suggest that the extracellular matrix of rat Pacinian corpuscles may contain molecules which are produced by Schwann cells and fibroblasts during maturation of the multilamellar auxiliary structures. The molecules deposited into the extracellular matrix are able to influence the re-differentiation of multilamellar auxiliary structures from immature cells.

Česky

Vnitřní sloupec Paciniho tělísek je tvořen specializovanými Schwannovými buňkami. Po mrazové evakuaci a denervaci dochází k obnově těchto struktur bez přítomnosti axonu.

Návaznosti

GA309/97/0107, projekt VaV

Název: Exprese integrinů při diferenciaci Schwannových buněk a odvozených struktur v periferní nervové soustavě laboratorního potkana

Investor: Grantová agentura ČR, Exprese integrinů při diferenciaci Schwannových buněk a odvozených struktur v periferní nervové soustavě laboratorního potkana

Citovat

DUBOVÝ, Petr. Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation. Anatomy and Embryology. Heidelberg: Springer-Verlag, 2000, roč. 202, č. 3, s. 235-245. ISSN 0340-2061.

@article{335051,
   author = {Dubový, Petr},
   article_location = {Heidelberg},
   article_number = {3},
   keywords = {inner core; Schwann cells},
   language = {eng},
   issn = {0340-2061},
   journal = {Anatomy and Embryology},
   title = {Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation},
   volume = {202},
   year = {2000}
}

TY  - JOUR
ID  - 335051
AU  - Dubový, Petr
PY  - 2000
TI  - Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation
JF  - Anatomy and Embryology
VL  - 202
IS  - 3
SP  - 235
EP  - 235
PB  - Springer-Verlag
SN  - 03402061
KW  - inner core
KW  - Schwann cells
N2  - The capsule and inner core are multilamellar auxiliary structures enveloping the axon terminal of the Pacinian corpuscle. The freezing injury of the rat interosseal Pacinian corpuscles induced the destruction of all cellular components while the extracellular matrix including the basal laminae survive the treatment. Simultaneous denervation and the freezing treatment of the Pacinian corpuscles discovered an ability of the basal lamina and other components of the extracellular matrix to stimulate a differentiation of migrated Schwann cells and fibroblasts into multilamellar auxiliary structures. The restoration of inner core and capsule in the Pacinian corpuscles was independent of the presence of sensory axon terminals. The restored lamellar structures of Pacinian corpuscles in long-term surviving rat (4 to 8 months) displayed atrophic changes. The results suggest that the extracellular matrix of rat Pacinian corpuscles may contain molecules which are produced by Schwann cells and fibroblasts during maturation of the multilamellar auxiliary structures. The molecules deposited into the extracellular matrix are able to influence the re-differentiation of multilamellar auxiliary structures from immature cells.
ER  -

DUBOVÝ, Petr. Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation. \textit{Anatomy and Embryology}. Heidelberg: Springer-Verlag, 2000, roč.~202, č.~3, s.~235-245. ISSN~0340-2061.

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