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@article{342739,
author = {Divišová, Hana and Havlišová, Helena and Borek, Petr and Pazdera, Pavel},
article_location = {Basel},
article_number = {5},
language = {eng},
issn = {1420-3049},
journal = {Molecules},
title = {One-pot Syntheses of Fused Quinazolines by Reaction of N-(2-Cyanophenyl)chloromethanimidoyl Chloride. I. A New Synthesis of 1,3-Oxazolo- and 1,3-Oxazino[2,3-b]quinazolines},
volume = {5},
year = {2000}
}
TY - JOUR
ID - 342739
AU - Divišová, Hana - Havlišová, Helena - Borek, Petr - Pazdera, Pavel
PY - 2000
TI - One-pot Syntheses of Fused Quinazolines by Reaction of N-(2-Cyanophenyl)chloromethanimidoyl Chloride. I. A New Synthesis of 1,3-Oxazolo- and 1,3-Oxazino[2,3-b]quinazolines
JF - Molecules
VL - 5
IS - 5
SP - 1166
EP - 1166
PB - MDPI
SN - 14203049
N2 - 12H-Benzo[1,3]oxazolo[2,3-b]quinazolin-12-imine, 9-chloro-12H-benzo[ 1,3]oxazolo[2,3-b]quinazolin-12-imine, 2,3-dihydro-5H-[1,3]oxazolo[2,3- b]quinazolin-5-imine, 2,3-dihydro-3,3-dimethyl-5H-[1,3]oxazolo[2,3-b]quinazolin-5-imine and 3,4-dihydro-2H,6H-[1,3]oxazino[2,3-b]quinazolin-6-imine were synthesized in a one-pot reaction of N-(2-cyanophenyl)chloromethanimidoyl chloride with 2-aminophenols, 2-aminoethanol, and 3-aminopropanol in the presence of a base. The course of the reaction was controlled by the temperature and the amount of base used. N-(2- Cyanophenyl)-(2-hydroxyanilino)methanimidoyl chloride, 2-chloro-3-(2-hydroxy-phenyl)-3,4-dihydroquinazolin-4-imine and 6-imino-2H, 3H, 4H, 6H, 11H-1,3-oxazino[2,3-b]-5-quinazolinium chloride were identified as intermediates of the one-pot process.
ER -
DIVIŠOVÁ, Hana, Helena HAVLIŠOVÁ, Petr BOREK a Pavel PAZDERA. One-pot Syntheses of Fused Quinazolines by Reaction of N-(2-Cyanophenyl)chloromethanimidoyl Chloride. I. A New Synthesis of 1,3-Oxazolo- and 1,3-Oxazino[2,3-b]quinazolines. \textit{Molecules}. Basel: MDPI, 2000, roč.~5, č.~5, s.~1166-1174. ISSN~1420-3049.
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