Relations between behavioral risk factors and genomic
constitution in essential hypertension

J 2000

Relations between behavioral risk factors and genomic constitution in essential hypertension

VAŠKŮ, Anna, Lydie IZAKOVIČOVÁ HOLLÁ a Miloslav KUKLETA

Základní údaje

Originální název

Relations between behavioral risk factors and genomic constitution in essential hypertension

Autoři

VAŠKŮ, Anna (203 Česká republika, garant), Lydie IZAKOVIČOVÁ HOLLÁ (203 Česká republika) a Miloslav KUKLETA (203 Česká republika)

Vydání

Homeostasis, Praha, Foun. for Stress Prevent. and Behav. Med, 2000, 1960-7560

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/00:00002862

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

ambulatory blood pressure monitoring; smoking; obesity; alcohol consumption; TABP score; emotional load; essential hypertension

Štítky

alcohol consumption, Ambulatory blood pressure monitoring, emotional load, essential hypertension, obesity, Smoking, TABP score

Změněno: 24. 4. 2003 10:25, prof. MUDr. Anna Vašků, CSc.

Anotace

V originále

The aim of the study was to associate alleles and/or genotype of the candidate gene polymorphisms for essential hypertension with some known cardiovascular risk factors as blood pressure parameters, smoking, alcohol consumption, obesity, type A behavioral pattern score and emotional load in 202 hypertensives and 196 normotensives subjects. No significant association among the gene polymorphisms and normotensives-hypertensives, blood pressure parameters from ambulatory blood pressure monitoring, smoking, salt consumption, alcohol consumption, BMI were found when single gene differences were calculated. When genotype concurrence of the two polymorphisms was evaluated, marginal association with TABP score was found(P=0.030). Three genotypes (IITT, IDMT, DDMM) were found more frequently in subjects with higher emotional load compared to the other genotype combinations (P=0.064).

Návaznosti

GA306/93/2192, projekt VaV

Název: Polymorfismy genů pro angiotensinogen a angiotensin I konvertasu u esenciální hypertense.

Investor: Grantová agentura ČR, Polymorfismy genů pro angiotensinogen a angiotensin I konvertasu u esenciální hypertense

MSM 141100002, záměr

Název: Molekulární patofyziologie multigenních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Molekulární patofyziologie multigenních chorob

VS96097, projekt VaV

Název: Molekulární patofyziologie vybraných "civilizačních", multigenně podmíněných chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Molekulární patofyziologie vybraných "civilizačních", multigenně podmíněných chorob

Citovat

VAŠKŮ, Anna, Lydie IZAKOVIČOVÁ HOLLÁ a Miloslav KUKLETA. Relations between behavioral risk factors and genomic constitution in essential hypertension. Homeostasis. Praha: Foun. for Stress Prevent. and Behav. Med, 2000, roč. 40, 3-4, s. 149-151. ISSN 1960-7560.

@article{348933,
   author = {Vašků, Anna and Izakovičová Hollá, Lydie and Kukleta, Miloslav},
   article_location = {Praha},
   article_number = {3-4},
   keywords = {ambulatory blood pressure monitoring; smoking; obesity; alcohol consumption; TABP score; emotional load; essential hypertension},
   language = {eng},
   issn = {1960-7560},
   journal = {Homeostasis},
   title = {Relations between behavioral risk factors and genomic constitution in essential hypertension},
   volume = {40},
   year = {2000}
}

TY  - JOUR
ID  - 348933
AU  - Vašků, Anna - Izakovičová Hollá, Lydie - Kukleta, Miloslav
PY  - 2000
TI  - Relations between behavioral risk factors and genomic constitution in essential hypertension
JF  - Homeostasis
VL  - 40
IS  - 3-4
SP  - 149
EP  - 149
PB  - Foun. for Stress Prevent. and Behav. Med
SN  - 19607560
KW  - ambulatory blood pressure monitoring
KW  - smoking
KW  - obesity
KW  - alcohol consumption
KW  - TABP score
KW  - emotional load
KW  - essential hypertension
N2  - The aim of the study was to associate alleles and/or genotype of the candidate gene polymorphisms for essential hypertension with some known cardiovascular risk factors as blood pressure parameters, smoking, alcohol consumption, obesity, type A behavioral pattern score and emotional load in 202 hypertensives and 196 normotensives subjects. No significant association among the gene polymorphisms and normotensives-hypertensives, blood pressure parameters from ambulatory blood pressure monitoring, smoking, salt consumption, alcohol consumption, BMI were found when single gene differences were calculated. When genotype concurrence of the two polymorphisms was evaluated, marginal association with TABP score was found(P=0.030). Three genotypes (IITT, IDMT, DDMM) were found more frequently in subjects with higher emotional load compared to the other genotype combinations (P=0.064).
ER  -

VAŠKŮ, Anna, Lydie IZAKOVIČOVÁ HOLLÁ a Miloslav KUKLETA. Relations between behavioral risk factors and genomic constitution in essential hypertension. \textit{Homeostasis}. Praha: Foun. for Stress Prevent. and Behav. Med, 2000, roč.~40, 3-4, s.~149-151. ISSN~1960-7560.

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