1995
Analysis of zinc, iron, and copper levels in patients with common variable immunodeficiency.
LITZMAN, Jiří, Milan DASTYCH a Pavel HEGARZákladní údaje
Originální název
Analysis of zinc, iron, and copper levels in patients with common variable immunodeficiency.
Autoři
LITZMAN, Jiří (203 Česká republika, garant), Milan DASTYCH (203 Česká republika) a Pavel HEGAR (203 Česká republika)
Vydání
Allergol. Immunopathol, Madrid, Editorial Grasi, 1995, 0211-6448
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30200 3.2 Clinical medicine
Stát vydavatele
Španělsko
Utajení
není předmětem státního či obchodního tajemství
Kód RIV
RIV/00216224:14110/95:00030427
Organizační jednotka
Lékařská fakulta
Klíčová slova anglicky
Common variable immunodeficiency; Nutritional status; Zinc; Irin; Copper
Změněno: 22. 6. 2009 16:44, prof. MUDr. Jiří Litzman, CSc.
V originále
Serum zinc, copper and iron levels together with content of zinc in hair were investigated in 13 patients with common variable immunodeficiency (CVID) and in 13 controls. A significant decrease in serum zinc (mean = 11.3 mumol/l, SD = 2.9 in CVID patients compared to mean 14.3 mumol/l, SD = 2.4 in controls) and iron levels (mean = 11.8 mumol/l, SD = 3.1 in CVID patients, mean = 18.3 mumol/l, SD = 4.7 in controls) in CVID patients were observed. Hair zinc content of CVID patients was significantly decreased compared to healthy persons (1.41 mumol/g, SD = 0.64 in CVID patients, and mean = 2.23 mumol/g, SD = 0.83 in controls). Serum copper level in CVID patients was significantly increased compared to controls (mean = 24.4 mumol/l, SD = 4.8 in CVID Patients, mean = 14.6 mumol/l, SD = 2.8 in controls). The decreased serum zinc and iron levels may be caused by disturbed absorption in the intestines of patients with CVID, but redistribution due to chronic inflammatory processes is a second possible explanation of hypozincemia in CVID patients
Česky
Byly analyzovány hladin Zn, Fe a Cu u nemocných s primárními humorálními imunodefcity.