J 1995

Analysis of zinc, iron, and copper levels in patients with common variable immunodeficiency.

LITZMAN, Jiří, Milan DASTYCH a Pavel HEGAR

Základní údaje

Originální název

Analysis of zinc, iron, and copper levels in patients with common variable immunodeficiency.

Autoři

LITZMAN, Jiří (203 Česká republika, garant), Milan DASTYCH (203 Česká republika) a Pavel HEGAR (203 Česká republika)

Vydání

Allergol. Immunopathol, Madrid, Editorial Grasi, 1995, 0211-6448

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Španělsko

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/95:00030427

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Common variable immunodeficiency; Nutritional status; Zinc; Irin; Copper
Změněno: 22. 6. 2009 16:44, prof. MUDr. Jiří Litzman, CSc.

Anotace

V originále

Serum zinc, copper and iron levels together with content of zinc in hair were investigated in 13 patients with common variable immunodeficiency (CVID) and in 13 controls. A significant decrease in serum zinc (mean = 11.3 mumol/l, SD = 2.9 in CVID patients compared to mean 14.3 mumol/l, SD = 2.4 in controls) and iron levels (mean = 11.8 mumol/l, SD = 3.1 in CVID patients, mean = 18.3 mumol/l, SD = 4.7 in controls) in CVID patients were observed. Hair zinc content of CVID patients was significantly decreased compared to healthy persons (1.41 mumol/g, SD = 0.64 in CVID patients, and mean = 2.23 mumol/g, SD = 0.83 in controls). Serum copper level in CVID patients was significantly increased compared to controls (mean = 24.4 mumol/l, SD = 4.8 in CVID Patients, mean = 14.6 mumol/l, SD = 2.8 in controls). The decreased serum zinc and iron levels may be caused by disturbed absorption in the intestines of patients with CVID, but redistribution due to chronic inflammatory processes is a second possible explanation of hypozincemia in CVID patients

Česky

Byly analyzovány hladin Zn, Fe a Cu u nemocných s primárními humorálními imunodefcity.