Reinnervation of the rat biceps brachii muscle through the
cellular and acellular nerve grafts introduced into the ventral
horn of the spinal cord

D 2000

Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL

Základní údaje

Originální název

Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord

Název česky

Reinervace m. biceps brachii přes celulární a acelulární nervový štěp

Autoři

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL

Vydání

2000. vyd. California, The AANS-CNS Book, s. 101-101, 2000

Nakladatel

AANS-CNS

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/00:00003129

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

acellular; cellular; nerve graft

Štítky

acellular, cellular, nerve graft

Změněno: 17. 6. 2009 11:35, prof. RNDr. Petr Dubový, CSc.

Anotace

ORIG CZ

V originále

The cellular and acellular nerve grafts were utilized to repair a functional connection between the motoneuron pool of the cervical spinal cord and the biceps brachii muscle through the musculocutaneous nerve. The were sutured with either cellular and acellular nerve grafts prepared from the saphenous nerve of the same animal. The one end of graft was sutured with the musculocutaneous nerve stump, the opposite end of the graft was introduced into the cervical spinal cord cranially to the avulsed C5 ventral root. The functional reinnervation of the biceps brachii muscle was evaluated by means of the behavioral (grooming) test, and electrophysiological methods. The presence of myelinated and unmyelinated axons in the nerve grafts and the musculocutaneous nerve stump was demonstrated by light and electron microscope. Our results demonstrate reinnervation of the musculocutaneous nerve via both cellular and acellular nerve grafts by axonal sprouts of the cervical motoneurons. Prior to axon regeneration, the acellular nerve graft was repopulated by Schwann cells migrating from the musculocutaneous nerve stump. The reinnervation by the way of acellular nerve graft was delayed and worse compared with the cellular graft.

Česky

Celulární a acelulární nervový štěp byl použit k reinervaci m. biceps brachii.

Návaznosti

GA309/00/0407, projekt VaV

Název: Celulární a extracelulární prostředí pro regeneraci axonů při kořenových a distálních lezích periferních nervů

Investor: Grantová agentura ČR, Celulární a extracelulární prostředí pro regeneraci axonů při kořenových a distálních lezích periferních nervů

Citovat

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL. Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord. In The AANS-CNS Book. 2000. vyd. California: AANS-CNS, 2000, s. 101.

@inproceedings{358831,
   author = {Haninec, Pavel and Dubový, Petr and Houšťava, Ladislav and Stejskal, Ladislav},
   address = {California},
   booktitle = {The AANS-CNS Book},
   edition = {2000},
   keywords = {acellular; cellular; nerve graft},
   language = {eng},
   location = {California},
   pages = {101-101},
   publisher = {AANS-CNS},
   title = {Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord},
   year = {2000}
}

TY  - CONF
ID  - 358831
AU  - Haninec, Pavel - Dubový, Petr - Houšťava, Ladislav - Stejskal, Ladislav
PY  - 2000
TI  - Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord
PB  - AANS-CNS
CY  - California
KW  - acellular
KW  - cellular
KW  - nerve graft
N2  - The cellular and acellular nerve grafts were utilized to repair a functional connection between the motoneuron pool of the cervical spinal cord and the biceps brachii muscle through the musculocutaneous nerve. The were sutured with either cellular and acellular nerve grafts prepared from the saphenous nerve of the same animal. The one end of graft was sutured with the musculocutaneous nerve stump, the opposite end of the graft was introduced into the cervical spinal cord cranially to the avulsed C5 ventral root. The functional reinnervation of the biceps brachii muscle was evaluated by means of the behavioral (grooming) test, and electrophysiological methods. The presence of myelinated and unmyelinated axons in the nerve grafts and the musculocutaneous nerve stump was demonstrated by light and electron microscope. Our results demonstrate reinnervation of the musculocutaneous nerve via both cellular and acellular nerve grafts by axonal sprouts of the cervical motoneurons. Prior to axon regeneration, the acellular nerve graft was repopulated by Schwann cells migrating from the musculocutaneous nerve stump. The reinnervation by the way of acellular nerve graft was delayed and worse compared with the cellular graft.
ER  -

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL. Reinnervation of the rat biceps brachii muscle through the cellular and acellular nerve grafts introduced into the ventral horn of the spinal cord. In \textit{The AANS-CNS Book}. 2000. vyd. California: AANS-CNS, 2000, s.~101.

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