| MCGRATH, Deirdre, Patrick J FOLEY, Martin PETREK, Lydie IZAKOVIČOVÁ HOLLÁ, Vítězslav KOLEK, Srihari VEERARAGHAVAN, Penelope A LYMPANY, Panagiotis PANTELIDIS, Anna VAŠKŮ, Athol U WELLS, Kenneth I WELSH and Roland M DU BOIS. ACE gene I/D polymorphism and pulmonary disease severity in UK and Czech sarcoidosis populations. Am.J.Respir.Crit.Care Med. Chicago: American Thoracic Society, 2001, vol. 164, No 2, p. 197-201. ISSN 1073-449X. |
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@article{361752,
author = {McGrath, Deirdre and Foley, Patrick J and Petrek, Martin and Izakovičová Hollá, Lydie and Kolek, Vítězslav and Veeraraghavan, Srihari and Lympany, Penelope A and Pantelidis, Panagiotis and Vašků, Anna and Wells, Athol U and Welsh, Kenneth I and du Bois, Roland M},
article_location = {Chicago},
article_number = {2},
keywords = {gene; polymorphism; ACE; sarcoidosis; severity; disease susceptibility},
language = {eng},
issn = {1073-449X},
journal = {Am.J.Respir.Crit.Care Med},
title = {ACE gene I/D polymorphism and pulmonary disease severity in UK and Czech sarcoidosis populations},
volume = {164},
year = {2001}
}
TY - JOUR
ID - 361752
AU - McGrath, Deirdre - Foley, Patrick J - Petrek, Martin - Izakovičová Hollá, Lydie - Kolek, Vítězslav - Veeraraghavan, Srihari - Lympany, Penelope A - Pantelidis, Panagiotis - Vašků, Anna - Wells, Athol U - Welsh, Kenneth I - du Bois, Roland M
PY - 2001
TI - ACE gene I/D polymorphism and pulmonary disease severity in UK and Czech sarcoidosis populations
JF - Am.J.Respir.Crit.Care Med
VL - 164
IS - 2
SP - 197
EP - 197
PB - American Thoracic Society
SN - 1073449X
KW - gene
KW - polymorphism
KW - ACE
KW - sarcoidosis
KW - severity
KW - disease susceptibility
N2 - Previous studies of the Insertion/Deletion (I/D) polymorphism of the Angiotensin-Converting Enzyme (ACE) gene in sarcoidosis have revealed both ethnic heterogeneity of I/D frequencies and controversy surrounding the association between the polymorphism and severity of disease. The objective of this study was, therefore, to clarify the role of the ACE I/D polymorphism in, 1) disease susceptibility, 2) pulmonary disease severity (with particular reference to pulmonary fibrosis) and 3) pulmonary disease progression, in two distinct European sarcoidosis populations.
ER -
MCGRATH, Deirdre, Patrick J FOLEY, Martin PETREK, Lydie IZAKOVIČOVÁ HOLLÁ, Vítězslav KOLEK, Srihari VEERARAGHAVAN, Penelope A LYMPANY, Panagiotis PANTELIDIS, Anna VAŠKŮ, Athol U WELLS, Kenneth I WELSH and Roland M DU BOIS. ACE gene I/D polymorphism and pulmonary disease severity in UK and Czech sarcoidosis populations. \textit{Am.J.Respir.Crit.Care Med}. Chicago: American Thoracic Society, 2001, vol.~164, No~2, p.~197-201. ISSN~1073-449X.
|
