Capillary zone electrophoresis and artificial neural networks
for estimation of the post-mortem interval (PMI) using
electrolytes measurements in human vetreous humour

J 2002

Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour

BOCAZ BENEVENTI, Gaston Guiller; F. TAGLIARO; F. BORTOLOTTI; G. MANETTO; Josef HAVEL et al.

Základní údaje

Originální název

Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour

Autoři

BOCAZ BENEVENTI, Gaston Guiller; F. TAGLIARO; F. BORTOLOTTI; G. MANETTO a Josef HAVEL

Vydání

International journal of legal medicine, Germany, Springer, 2002, 0937-9827

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10406 Analytical chemistry

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.918

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/02:00005630

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

capillary zone electrophoresis; artificial neural networks; post-mortem interval

Štítky

artificial neural networks, Capillary Zone Electrophoresis, post-mortem interval

Změněno: 2. 6. 2003 13:15, prof. RNDr. Josef Havel, DrSc.

Anotace

V originále

Determination of electrolyte concentrations in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval. On the basis of its well known potential in ion analysis, capillary zone electrophoresis has recently been applied to achieve a rapid and simultaneous determination of inorganic ions in this extracellular fluid. In the present work, artificial neural networks were applied for modelling of the relationship of multicomponent CZE analysis of K+, NH4+, Na+ and Ba2+ ions in vitreous humour with PMI. In a study based on 61 cases with different causes of death and a known PMI ranging from 3 to 144 h, the use of ANNs considering all inorganic ion data from the human vitreous humour, achieved a substantial improvement of post-mortem interval prediction. Good linear correlation was observed and in comparison to the traditional linear least squares method applied only to K+ levels in the vitreous humour, the prediction of PMI with ANN was improved by a factor of 5 from 15 h to less than 3 h.

Návaznosti

MSM 143100011, záměr

Název: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů

Citovat

BOCAZ BENEVENTI, Gaston Guiller; F. TAGLIARO; F. BORTOLOTTI; G. MANETTO a Josef HAVEL. Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour. International journal of legal medicine. Germany: Springer, 2002, roč. 116, č. 1, s. 5-10. ISSN 0937-9827.

@article{402191,
   author = {Bocaz Beneventi, Gaston Guiller and Tagliaro, F. and Bortolotti, F. and Manetto, G. and Havel, Josef},
   article_location = {Germany},
   article_number = {1},
   keywords = {capillary zone electrophoresis; artificial neural networks; post-mortem interval},
   language = {eng},
   issn = {0937-9827},
   journal = {International journal of legal medicine},
   title = {Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour},
   volume = {116},
   year = {2002}
}

TY  - JOUR
ID  - 402191
AU  - Bocaz Beneventi, Gaston Guiller - Tagliaro, F. - Bortolotti, F. - Manetto, G. - Havel, Josef
PY  - 2002
TI  - Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour
JF  - International journal of legal medicine
VL  - 116
IS  - 1
SP  - 5
EP  - 5
PB  - Springer
SN  - 09379827
KW  - capillary zone electrophoresis
KW  - artificial neural networks
KW  - post-mortem interval
N2  - Determination of electrolyte concentrations in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval. On the basis of its well known potential in ion analysis, capillary zone electrophoresis has recently been applied to achieve a rapid and simultaneous determination of inorganic ions in this extracellular fluid. In the present work, artificial neural networks were applied for modelling of the relationship of multicomponent CZE analysis of K+, NH4+, Na+ and Ba2+ ions in vitreous humour with PMI. In a study based on 61 cases with different causes of death and a known PMI ranging from 3 to 144 h, the use of ANNs considering all inorganic ion data from the human vitreous humour, achieved a substantial improvement of post-mortem interval prediction. Good linear correlation was observed and in comparison to the traditional linear least squares method applied only to K+ levels in the vitreous humour, the prediction of PMI with ANN was improved by a factor of 5 from 15 h to less than 3 h.
ER  -

BOCAZ BENEVENTI, Gaston Guiller; F. TAGLIARO; F. BORTOLOTTI; G. MANETTO a Josef HAVEL. Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour. \textit{International journal of legal medicine}. Germany: Springer, 2002, roč.~116, č.~1, s.~5-10. ISSN~0937-9827.

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