a 2002

The role of actin cytoskeleton in apoptotic cell death

NERADIL, Jakub, Renata VESELSKÁ, Karel ZITTERBART and Augustin SVOBODA

Basic information

Original name

The role of actin cytoskeleton in apoptotic cell death

Authors

NERADIL, Jakub (203 Czech Republic, guarantor), Renata VESELSKÁ (203 Czech Republic), Karel ZITTERBART (203 Czech Republic) and Augustin SVOBODA (203 Czech Republic)

Edition

10th Euroconference on Apoptosis - "Charming to Death" 2002

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/02:00006514

Organization unit

Faculty of Medicine

Keywords in English

induced differentiation; apoptosis; actin cytoskeleton; HL-60 cell line; P19 cell line

Tags

Změněno: 6/4/2010 20:21, prof. RNDr. Renata Veselská, Ph.D., M.Sc.

Abstract

V originále

Morphology of the actin cytoskeleton during apoptosis associated with the process of induced differentiation was studied on P19 and HL-60 cell lines using transmission electron microscopy, epifluorescence and confocal microscopy. Actin cytoskeleton underwent specific alterations and rearrangements during the apoptotic process. These structural changes are common for the apoptotic cell death, play the active role in the morphological features of apoptosis and they are independent on the course of differentiation associated with apoptosis induction.

Links

GA304/00/0403, research and development project
Name: Změny cytoskeletu buněk nádorových linií v průběhu indukované apoptózy v závislosti na stádiu diferenciace.
Investor: Czech Science Foundation, Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation