| LI, Hua, YX ZHANG, Pavla POLÁŠKOVÁ a Josef HAVEL. Enhancement of precision in the analysis of medicines by capillary electrophoresis using artificial neural networks. ACTA CHIMICA SINICA. BEIJING: SCIENCE CHINA PRESS, 2002, roč. 60, č. 7, s. 1264-1268. ISSN 0567-7351. |
Další formáty:
BibTeX
LaTeX
RIS
@article{485223,
author = {Li, Hua and Zhang, YX and Polášková, Pavla and Havel, Josef},
article_location = {BEIJING},
article_number = {7},
keywords = {Enhancement of precision; analysis of medicines; capillary electrophoresis},
language = {eng},
issn = {0567-7351},
journal = {ACTA CHIMICA SINICA},
title = {Enhancement of precision in the analysis of medicines by capillary electrophoresis using artificial neural networks},
volume = {60},
year = {2002}
}
TY - JOUR
ID - 485223
AU - Li, Hua - Zhang, YX - Polášková, Pavla - Havel, Josef
PY - 2002
TI - Enhancement of precision in the analysis of medicines by capillary electrophoresis using artificial neural networks
JF - ACTA CHIMICA SINICA
VL - 60
IS - 7
SP - 1264-1268
EP - 1264-1268
PB - SCIENCE CHINA PRESS
SN - 05677351
KW - Enhancement of precision
KW - analysis of medicines
KW - capillary electrophoresis
N2 - Possibility of increasing the precision of quantitative determination of memantine by capillary electrophoresis (CE) was studied using artificial neural networks (ANNs). ANNs show their unique merits in the calibration of non-linear models. In the analysis of memantine by CE, there is no obvious linear relationships between the concentrations of the memantine and its peak areas or heights, or even their ratios to those of the corresponding internal standards, respectively. The greatest advantage of ANNs is that no prior knowledge of migration behavior and separation system is needed. The inputs of the ANNs were the peak areas and heights of memantine, and the outputs were the concentrations of the memantine. The 2:2: 1 ANNs gave excellent results. The ANNs approach can also he used to improve the precision of determination of other kinds of analytes for its general validity.
ER -
LI, Hua, YX ZHANG, Pavla POLÁŠKOVÁ a Josef HAVEL. Enhancement of precision in the analysis of medicines by capillary electrophoresis using artificial neural networks. \textit{ACTA CHIMICA SINICA}. BEIJING: SCIENCE CHINA PRESS, 2002, roč.~60, č.~7, s.~1264-1268. ISSN~0567-7351.
|
