| HERMANOVÁ, Markéta, Z. LUKÁŠ, Iva KROUPOVÁ, Z. KLEIBL, Ivo NOVOTNÝ, R. NENUTIL, Marie PAZOURKOVÁ, J. BRÁZDIL, L. KŘEN a Petr DÍTĚ. Realtionship betwen K-ras mutation and the expression of p21 WAF1/CIP1 and p53 in chronic pankreatitis and pancreatic adenocarcinoma. Neoplasma. Bratislava: Slovak Academy of Sociences, 2003, roč. 50, č. 5, s. 319-325. ISSN 0028-2685. |
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@article{491507,
author = {Hermanová, Markéta and Lukáš, Z. and Kroupová, Iva and Kleibl, Z. and Novotný, Ivo and Nenutil, R. and Pazourková, Marie and Brázdil, J. and Křen, L. and Dítě, Petr},
article_location = {Bratislava},
article_number = {5},
keywords = {Pancreatic intraepihedial neoplasia; K-ras; p21WAF1/CIP1; p53},
language = {eng},
issn = {0028-2685},
journal = {Neoplasma},
title = {Realtionship betwen K-ras mutation and the expression of p21 WAF1/CIP1 and p53 in chronic pankreatitis and pancreatic adenocarcinoma},
volume = {50},
year = {2003}
}
TY - JOUR
ID - 491507
AU - Hermanová, Markéta - Lukáš, Z. - Kroupová, Iva - Kleibl, Z. - Novotný, Ivo - Nenutil, R. - Pazourková, Marie - Brázdil, J. - Křen, L. - Dítě, Petr
PY - 2003
TI - Realtionship betwen K-ras mutation and the expression of p21 WAF1/CIP1 and p53 in chronic pankreatitis and pancreatic adenocarcinoma
JF - Neoplasma
VL - 50
IS - 5
SP - 319-325
EP - 319-325
PB - Slovak Academy of Sociences
SN - 00282685
KW - Pancreatic intraepihedial neoplasia
KW - K-ras
KW - p21WAF1/CIP1
KW - p53
N2 - Overexpression of p21WAF1/CIP1wasrecently discribed as an early event in the development of pancreatic intraepihelial neoplasia. Since activating K-ras mutation are described in more than 80% of pancreatic cancers and are known to increase intracellular levels of p21WAF1/CIP1 in experimental models, the posible role of activating K-ras mutations in an induction of the p21WAF1/CIP1 expression was investigated in our study.
ER -
HERMANOVÁ, Markéta, Z. LUKÁŠ, Iva KROUPOVÁ, Z. KLEIBL, Ivo NOVOTNÝ, R. NENUTIL, Marie PAZOURKOVÁ, J. BRÁZDIL, L. KŘEN a Petr DÍTĚ. Realtionship betwen K-ras mutation and the expression of p21 WAF1/CIP1 and p53 in chronic pankreatitis and pancreatic adenocarcinoma. \textit{Neoplasma}. Bratislava: Slovak Academy of Sociences, 2003, roč.~50, č.~5, s.~319-325. ISSN~0028-2685.
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