Assessment of myocardial viability by acoustic densitometry in
patients with left ventricle dysfunction due to coronary artery
disease

J 2003

Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease

PANOVSKÝ, Roman; Jaroslav MELUZÍN; Vladimír KINCL; Blanka FISCHEROVÁ; František ŠTĚTKA et al.

Základní údaje

Originální název

Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease

Autoři

PANOVSKÝ, Roman; Jaroslav MELUZÍN; Vladimír KINCL; Blanka FISCHEROVÁ a František ŠTĚTKA

Vydání

European Journal of Echocardiography, Exeter, Great Britain, Elsevier, 2003, 1525-2167

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/03:00009492

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

acoustic densitometry; viability; coronary artery disease

Štítky

acoustic densitometry, coronary artery disease, viability

Změněno: 1. 2. 2004 16:37, doc. MUDr. Roman Panovský, Ph.D.

Anotace

V originále

Aim: The purpose of our study was to assess whether acoustic densitometry could distinguish between viable and irreversible dysfunctional myocardium in patients with coronary artery disease before myocardial revascularization. Methods: Seventy patients with chronic coronary artery disease and dysfunctional myocardial segments before planned myocardial revascularization were examined by acoustic densitometry. Fifty four patients had revascularization of at least one coronary artery supplying dysfunctional segments. Control echocardiography of these patients was performed after 3 months after bypass surgery or percutaneous coronary intervention for assessing contractility of revascularized, initially dysfunctional myocardial segments. The dysfunctional segments were defined as viable if they exhibited improvement in their thickening after revascularization. Wall motion was scored using 16-segment model of left ventricle, acoustic densitometry was evaluated from parasternal long axis view, parasternal short axis view at the level of papilary muscles and apical four-chamber and two-chamber views. Amplitude of cyclic variation of integrated backscatter (CVIB) was evaluated from each dysfunctional segment. Optimal cut off value of CVIB for distinction between viable and irreversible dysfunctional myocardium was found using receiver operating characteristic curves. Results: Cut off values for anteroseptal, posterior, interventricular septal, lateral, inferior and anterior segments were 4,1; 4,3; 4,4; 4,2; 4,5; 4,0 and 4,2 decibels, respectively. Sensitivity, specificity, positive and negative predictive values for identification of myocardial viability by acoustic densitometry using this cut off values were 918%, 81%, 87%, and 86%, respectively. Conclusion: Acoustic densitometry can differentiate viable and irreversible dysfunctional myocardium in patients with coronary artery disease before myocardial revascularization.

Citovat

PANOVSKÝ, Roman; Jaroslav MELUZÍN; Vladimír KINCL; Blanka FISCHEROVÁ a František ŠTĚTKA. Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease. European Journal of Echocardiography. Exeter, Great Britain: Elsevier, 2003, roč. 4, Suppl 1, s. S80, 1 s. ISSN 1525-2167.

@article{492615,
   author = {Panovský, Roman and Meluzín, Jaroslav and Kincl, Vladimír and Fischerová, Blanka and Štětka, František},
   article_location = {Exeter, Great Britain},
   article_number = {Suppl 1},
   keywords = {acoustic densitometry; viability; coronary artery disease},
   language = {eng},
   issn = {1525-2167},
   journal = {European Journal of Echocardiography},
   title = {Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease},
   volume = {4},
   year = {2003}
}

TY  - JOUR
ID  - 492615
AU  - Panovský, Roman - Meluzín, Jaroslav - Kincl, Vladimír - Fischerová, Blanka - Štětka, František
PY  - 2003
TI  - Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease
JF  - European Journal of Echocardiography
VL  - 4
IS  - Suppl 1
SP  - S80
EP  - S80
PB  - Elsevier
SN  - 15252167
KW  - acoustic densitometry
KW  - viability
KW  - coronary artery disease
N2  - Aim: The purpose of our study was to assess whether acoustic densitometry could distinguish between viable and irreversible dysfunctional myocardium in patients with coronary artery disease before myocardial revascularization. Methods: Seventy patients with chronic coronary artery disease and dysfunctional myocardial segments before planned myocardial revascularization were examined by acoustic densitometry. Fifty four patients had revascularization of at least one coronary artery supplying dysfunctional segments. Control echocardiography of these patients was performed after 3 months after bypass surgery or percutaneous coronary intervention for assessing contractility of revascularized, initially dysfunctional myocardial segments. The dysfunctional segments were defined as viable if they exhibited improvement in their thickening after revascularization. Wall motion was scored using 16-segment model of left ventricle, acoustic densitometry was evaluated from parasternal long axis view, parasternal short axis view at the level of papilary muscles and apical four-chamber and two-chamber views. Amplitude of cyclic variation of integrated backscatter (CVIB) was evaluated from each dysfunctional segment. Optimal cut off value of CVIB for distinction between viable and irreversible dysfunctional myocardium was found using receiver operating characteristic curves. Results: Cut off values for anteroseptal, posterior, interventricular septal, lateral, inferior and anterior segments were 4,1; 4,3; 4,4; 4,2; 4,5; 4,0 and 4,2 decibels, respectively. Sensitivity, specificity, positive and negative predictive values for identification of myocardial viability by acoustic densitometry using this cut off values were 918%, 81%, 87%, and 86%, respectively. Conclusion: Acoustic densitometry can differentiate viable and irreversible dysfunctional myocardium in patients with coronary artery disease before myocardial revascularization.
ER  -

PANOVSKÝ, Roman; Jaroslav MELUZÍN; Vladimír KINCL; Blanka FISCHEROVÁ a František ŠTĚTKA. Assessment of myocardial viability by acoustic densitometry in patients with left ventricle dysfunction due to coronary artery disease. \textit{European Journal of Echocardiography}. Exeter, Great Britain: Elsevier, 2003, roč.~4, Suppl 1, s.~S80, 1 s. ISSN~1525-2167.

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