D 2004

Prognostic factors of the Pharynx and supraglottic Carcinoma

KOSTŘICA, Rom; Pavel SMILEK; Jan ROTTENBERG; Karel VESELÝ; Ladislav DUŠEK et al.

Základní údaje

Originální název

Prognostic factors of the Pharynx and supraglottic Carcinoma

Název anglicky

Prognostic factors of the Pharynx and supraglottic Carcinoma

Autoři

KOSTŘICA, Rom; Pavel SMILEK ORCID; Jan ROTTENBERG; Karel VESELÝ; Ladislav DUŠEK a Jiří HLOŽEK

Vydání

Stuttgart, HNO Infromationen, s. 139-139, 2004

Nakladatel

Karl Demetr Verlag im Georg Thieme VErlag

Další údaje

Jazyk

čeština

Typ výsledku

Stať ve sborníku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/04:00010082

Organizační jednotka

Lékařská fakulta

ISBN

03 44-93 19

Klíčová slova anglicky

Prognosis of head and neck carcinoma - DNA content - Ki-67
Změněno: 2. 6. 2004 08:02, doc. MUDr. Pavel Smilek, Ph.D.

Anotace

V originále

The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis treated at the Clinic of Otorhinolaryngology and Head and Neck Surgery in Brno within 1991 - 1999. Besides routine examinations, flow cytometric analysis of DNA was performed and Ki-67 marker was established by means of immunohistochemistry. The evaluation of kinetic parameters of the cellular cycle has revealed quite clearly the significantly lower share of SPF in tumors with poor prognosis. Tumors with direct progression immediately after treatment have shown statistically significantly higher share of cells in G2/M phase.

Anglicky

The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis treated at the Clinic of Otorhinolaryngology and Head and Neck Surgery in Brno within 1991 - 1999. Besides routine examinations, flow cytometric analysis of DNA was performed and Ki-67 marker was established by means of immunohistochemistry. The evaluation of kinetic parameters of the cellular cycle has revealed quite clearly the significantly lower share of SPF in tumors with poor prognosis. Tumors with direct progression immediately after treatment have shown statistically significantly higher share of cells in G2/M phase.

Návaznosti

MSM 141100003, záměr
Název: Zevní prostředí - karcinogeneze - onkologie
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Zevní prostředí - karcinogeneze - onkologie