ŠEDO, Ondrej, Klára NOVOTNÁ and Josef HAVEL. Advantages of derivatization by osmium tetroxide and 2,2 '-bipyridine for matrix-assisted laser desorption/ionization post-source decay fragment ion analysis of peptides. Rapid Communications in Mass Spectrometry. 2004, vol. 18, No 3, p. 339-344. ISSN 0951-4198.
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Basic information
Original name Advantages of derivatization by osmium tetroxide and 2,2 '-bipyridine for matrix-assisted laser desorption/ionization post-source decay fragment ion analysis of peptides
Name in Czech Výhody derivatizace peptidů činidlem oxid osmičelý-bipyridin z hlediska jejich rozpadu za iontovým zdrojem po ionizaci a desorpci za účasti matrice
Authors ŠEDO, Ondrej (203 Czech Republic), Klára NOVOTNÁ (203 Czech Republic) and Josef HAVEL (203 Czech Republic, guarantor).
Edition Rapid Communications in Mass Spectrometry, 2004, 0951-4198.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10406 Analytical chemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.750
RIV identification code RIV/00216224:14310/04:00011463
Organization unit Faculty of Science
UT WoS 000188695200016
Keywords in English MALDI-TOF MS; PSD; Os;bipy; [Gly14]-humanin derivatives;
Tags bipy, MALDI-TOF MS, Os, PSD, [Gly14]-humanin derivatives
Changed by Changed by: Mgr. Ondrej Šedo, Ph.D., učo 13589. Changed: 14/2/2005 14:12.
Abstract
Matrix-assisted laser desorption/ionization-post-source decay (MALDI-PSD) fragment ion analysis is frequently used for peptide sequence determination. PSD fragmentation is often changed or improved in terms of, e.g., sequence coverage, after derivatization. In this work, the influence of modification by an osmium tetroxide-bipyridine reagent (Os,bipy) on the MALDI-PSD behaviour of peptides is studied.
Abstract (in Czech)
Byl studován vliv derivatizace peptidů činidlem oxid osmičelý-bipyridin na jejich chování během rozpadu za iontovým zdrojem po ionizaci MALDI.
Links
GA305/03/1100, research and development projectName: Syntéza a studium neuroprotektivních peptidů odvozených od humaninu
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