Schwann cells and endoneurial extracellular matrix molecules as
potential cues for sorting of regenerated axons: A review

J 2004

Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review

DUBOVÝ, Petr

Základní údaje

Originální název

Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review

Název česky

Schwannovy buňky a endoneuriální extracelulární matrix a jejich vliv na sortování regenerovaných axonů

Autoři

DUBOVÝ, Petr

Vydání

Anatomical Science International, 2004, 1447-6959

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Japonsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/04:00010572

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

nerve regeneration; selective reinnervation; sensory and motor axons

Štítky

nerve regeneration, selective reinnervation, sensory and motor axons

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 6. 2009 10:48, prof. RNDr. Petr Dubový, CSc.

Anotace

ORIG CZ

V originále

Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses.

Česky

V review jsou shrnuty vlastní a publikované výsledky naznačující vliv Schwannových buněk a endoneuriální extracelulární matrix na sortování regenerujících axonů v periferních nervech.

Návaznosti

GA309/00/0407, projekt VaV

Název: Celulární a extracelulární prostředí pro regeneraci axonů při kořenových a distálních lezích periferních nervů

Investor: Grantová agentura ČR, Celulární a extracelulární prostředí pro regeneraci axonů při kořenových a distálních lezích periferních nervů

Citovat

DUBOVÝ, Petr. Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review. Anatomical Science International. 2004, roč. 79, č. 2, s. 198-208. ISSN 1447-6959.

@article{561600,
   author = {Dubový, Petr},
   article_number = {2},
   keywords = {nerve regeneration; selective reinnervation; sensory and motor axons},
   language = {eng},
   issn = {1447-6959},
   journal = {Anatomical Science International},
   title = {Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review},
   url = {http://www.scopus.com/record/display.url?view=extended&origin=recordpage&eid=2-s2.0-10944248377&noHighlight=false&sort=plf-f&src=s&st1=Dubovy+P&nlo=&nlr=&nls=&sid=YZ0Txkp8n2akK-75SmbVStm%3a90&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Dubovy+P%29&relpos=12},
   volume = {79},
   year = {2004}
}

TY  - JOUR
ID  - 561600
AU  - Dubový, Petr
PY  - 2004
TI  - Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review
JF  - Anatomical Science International
VL  - 79
IS  - 2
SP  - 198-208
EP  - 198-208
SN  - 14476959
KW  - nerve regeneration
KW  - selective reinnervation
KW  - sensory and motor axons
UR  - http://www.scopus.com/record/display.url?view=extended&origin=recordpage&eid=2-s2.0-10944248377&noHighlight=false&sort=plf-f&src=s&st1=Dubovy+P&nlo=&nlr=&nls=&sid=YZ0Txkp8n2akK-75SmbVStm%3a90&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Dubovy+P%29&relpos=12
N2  - Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses.
ER  -

DUBOVÝ, Petr. Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review. \textit{Anatomical Science International}. 2004, roč.~79, č.~2, s.~198-208. ISSN~1447-6959.

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