2005
PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS
SMILEK, Pavel, Rom KOSTŘICA, Jan ROTTENBERG, Karel VESELÝ, Ladislav DUŠEK et. al.Základní údaje
Originální název
PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS
Název česky
Prediktivní parametry karcinomu faryngu a supraglottis
Název anglicky
PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS
Autoři
SMILEK, Pavel, Rom KOSTŘICA, Jan ROTTENBERG, Karel VESELÝ a Ladislav DUŠEK
Vydání
Brno, Sborník abstrakt a program 68. kongresu České spol. pro otorinolaryngologii a chir. hlavy a krku, s. 111-111, 2005
Nakladatel
Medica Publishing and consulting s.r.o.
Další údaje
Jazyk
čeština
Typ výsledku
Stať ve sborníku
Obor
30200 3.2 Clinical medicine
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Organizační jednotka
Lékařská fakulta
ISBN
80-239-5112-2
Klíčová slova anglicky
head and neck cancer; prognosis; p53; DNA flow-cytometry
Štítky
Změněno: 22. 6. 2005 08:16, doc. MUDr. Pavel Smilek, Ph.D.
V originále
The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis. Besides routine examinations, flow cytometric analysis of was performed, p53 and Ki-67 markers were established by means of immunohistochemistry. Furthermore mitotic and apoptotic index were established. Cytokinetic parameters and proliferation activity were found as important predictors of the second level (after recognizing stage, grade and DNA status of the tumor). Early progressed cases have typically decreased SPF fraction combined with increased mitotic activity.
Anglicky
The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis. Besides routine examinations, flow cytometric analysis of was performed, p53 and Ki-67 markers were established by means of immunohistochemistry. Furthermore mitotic and apoptotic index were established. Cytokinetic parameters and proliferation activity were found as important predictors of the second level (after recognizing stage, grade and DNA status of the tumor). Early progressed cases have typically decreased SPF fraction combined with increased mitotic activity.