| PISTOVČÁKOVÁ, Jana a Alexandra ŠULCOVÁ. Behavioural effects of selected antiepileptics in mice defeated on social interactions. Behavioural Pharmacology. London: Lippincott Williams & Wilkins, 2005, roč. 16, Suppl.1, s. S42-S42, 1 s. ISSN 0955-8810. |
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@article{581862,
author = {Pistovčáková, Jana and Šulcová, Alexandra},
article_location = {London},
article_number = {Suppl.1},
keywords = {valproate; carbamazepine; lamotrigine; gabapentin; tiagabine; mice; depression; antiepileptic; social interactions},
language = {eng},
issn = {0955-8810},
journal = {Behavioural Pharmacology},
title = {Behavioural effects of selected antiepileptics in mice defeated on social interactions},
volume = {16},
year = {2005}
}
TY - JOUR
ID - 581862
AU - Pistovčáková, Jana - Šulcová, Alexandra
PY - 2005
TI - Behavioural effects of selected antiepileptics in mice defeated on social interactions
JF - Behavioural Pharmacology
VL - 16
IS - Suppl.1
SP - S42-S42
EP - S42-S42
PB - Lippincott Williams & Wilkins
SN - 09558810
KW - valproate
KW - carbamazepine
KW - lamotrigine
KW - gabapentin
KW - tiagabine
KW - mice
KW - depression
KW - antiepileptic
KW - social interactions
N2 - The model of behavioural response of the group-housed non-aggressive male mice repeatedly defeated on paired social interactions with singly-housed aggressive counterparts refers to the spectrum of social conflict-related behavioural profiles. These group-housed mice exhibit a suppressed ambulation in the subsequent open field test compared to the controls without such an aversive social experience. This type of inhibited behaviour might be a model for testing of antidepressant-like drug activities. The present study demonstrates utilisation of the method for analysis of psychotropic antidepressant-like drug effects. Despite that effects of lamotrigine and gabapentin, advocated at present as antidepressants, did not resemble effects of other drugs tested, all clinically used antidepressants (citalopram, valproate, carbamazepine) produced very similar disinhibition of the behaviour suppressed by social defeats.
ER -
PISTOVČÁKOVÁ, Jana a Alexandra ŠULCOVÁ. Behavioural effects of selected antiepileptics in mice defeated on social interactions. \textit{Behavioural Pharmacology}. London: Lippincott Williams \&{} Wilkins, 2005, roč.~16, Suppl.1, s.~S42-S42, 1 s. ISSN~0955-8810.
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