ŠIMEK, Zdeněk, Radim ŠVÁBENSKÝ a Kamila KOČÍ. Analytical Determination of Polycyclic Aromatic Nitrogen Heterocycles in the mixture with Polycyclioc Aromatic Hydrocarbons and their Derivatives. In Book of Abstracts-3rd Black Sea Basin Conference on Analytical Chemistry. Constanta, Romania: Ovidius University Press. s. 42-42. ISBN 614-291-4. 2005.
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Základní údaje
Originální název Analytical Determination of Polycyclic Aromatic Nitrogen Heterocycles in the mixture with Polycyclioc Aromatic Hydrocarbons and their Derivatives
Název česky Analytické stanovení polycyklických aromatických dusíkatých heterocyklů ve směsi s PAH a jejich deriváty.
Autoři ŠIMEK, Zdeněk (203 Česká republika, garant), Radim ŠVÁBENSKÝ (203 Česká republika) a Kamila KOČÍ (203 Česká republika).
Vydání Constanta, Romania, Book of Abstracts-3rd Black Sea Basin Conference on Analytical Chemistry, od s. 42-42, 1 s. 2005.
Nakladatel Ovidius University Press
Další údaje
Originální jazyk angličtina
Typ výsledku Stať ve sborníku
Obor 10406 Analytical chemistry
Stát vydavatele Rumunsko
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14310/05:00014612
Organizační jednotka Přírodovědecká fakulta
ISBN 614-291-4
Klíčová slova anglicky Polycyclic Aromatic Nitrogen Heterocycles; Polycyclioc Aromatic Hydrocarbons; Derivatives
Štítky DERIVATIVES, Polycyclic Aromatic Nitrogen Heterocycles, Polycyclioc Aromatic Hydrocarbons
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnil: doc. RNDr. Zdeněk Šimek, CSc., učo 37019. Změněno: 31. 1. 2008 15:58.
Anotace
The most used explosives contain nitroderivatives of toluene such as 2,4,6-trinitrotoluene (TNT). TNT, other trinitrotoluenes and products of their biotranformations, aminodinitrotoluenes (ADNT) and diaminonitrotoluenes (DANT) are widely distributed in the environment as a consequence of extensive usage in military zones and as a result of wrong handling. The various nitroaromatic compounds have been found as contaminants in soils at munitions manufacturing facilities, storage depots, and sites of the explosives use. TNT is often stepwise biologically reduced to aminodinitrotoluenes and diaminonitrotoluenes in the environment. They have mutagenic, carcinogenic and toxic effects. TNT, 2-ADNT, 4-ADNT, 2,4-DANT, 2,6-DANT have been found to be cytotoxic presumably due to induced oxidative stress. TNT, and the TNT-derived metabolites demonstrate mutagenic capability. According to EPA, TNT is possible human carcinogen. The most commonly used method for the analysis of nitrotoluenes and aminonitrotoluenes is high performance liquid chromatography (HPLC) with UV detection due to its widespread availability. At present, electromigration methods are used due to their unrivalled separation efficiency. Comparison of retention behaviour of selected nitroderivatives of toluene and aminonitroderivatives of toluene in high performance liquid chromatography (HPLC), with their electromigration behaviour in capillary electrochromatography (CEC) and micellar electrokinetic chromatography (MECC) separation systems is presented. Analytical column with octadecyl stationary phase was used for HPLC separation, fused silica capillary filled with octadecylsilica stationary phase was used for CEC experiments and the standard bare fused silica capillary for MECC. Effect of pH and concentration of background electrolyte, sodium dodecylsulphate (SDS) concentration and organic modifier content was investigated in electrophoretic methods. Effect of mobile phase composition and different gradient elutions was studied in reversed phase liquid chromatography system. The applicability of separation method under investigation for determination of nitroderivatives of toluene in environmental samples is discussed.
Anotace česky
The most used explosives contain nitroderivatives of toluene such as 2,4,6-trinitrotoluene (TNT). TNT, other trinitrotoluenes and products of their biotranformations, aminodinitrotoluenes (ADNT) and diaminonitrotoluenes (DANT) are widely distributed in the environment as a consequence of extensive usage in military zones and as a result of wrong handling. The various nitroaromatic compounds have been found as contaminants in soils at munitions manufacturing facilities, storage depots, and sites of the explosives use. TNT is often stepwise biologically reduced to aminodinitrotoluenes and diaminonitrotoluenes in the environment. They have mutagenic, carcinogenic and toxic effects. TNT, 2-ADNT, 4-ADNT, 2,4-DANT, 2,6-DANT have been found to be cytotoxic presumably due to induced oxidative stress. TNT, and the TNT-derived metabolites demonstrate mutagenic capability. According to EPA, TNT is possible human carcinogen. The most commonly used method for the analysis of nitrotoluenes and aminonitrotoluenes is high performance liquid chromatography (HPLC) with UV detection due to its widespread availability. At present, electromigration methods are used due to their unrivalled separation efficiency. Comparison of retention behaviour of selected nitroderivatives of toluene and aminonitroderivatives of toluene in high performance liquid chromatography (HPLC), with their electromigration behaviour in capillary electrochromatography (CEC) and micellar electrokinetic chromatography (MECC) separation systems is presented. Analytical column with octadecyl stationary phase was used for HPLC separation, fused silica capillary filled with octadecylsilica stationary phase was used for CEC experiments and the standard bare fused silica capillary for MECC. Effect of pH and concentration of background electrolyte, sodium dodecylsulphate (SDS) concentration and organic modifier content was investigated in electrophoretic methods. Effect of mobile phase composition and different gradient elutions was studied in reversed phase liquid chromatography system. The applicability of separation method under investigation for determination of nitroderivatives of toluene in environmental samples is discussed.
Návaznosti
MSM0021622412, záměrNázev: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Akronym: INCHEMBIOL)
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální , regionální a lokální úrovni
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