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@inproceedings{621710, author = {Pásek, Michal and Šimurda, Jiří and Orchard, Clive and Christé, Georges}, address = {Lyon}, booktitle = {Computers in cardiology 2005}, keywords = {cardiac cell; tubular system; quantitative modelling}, language = {eng}, location = {Lyon}, isbn = {0-7803-9337-6}, pages = {993-995}, publisher = {IEEE}, title = {Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study}, year = {2005} }
TY - JOUR ID - 621710 AU - Pásek, Michal - Šimurda, Jiří - Orchard, Clive - Christé, Georges PY - 2005 TI - Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study PB - IEEE CY - Lyon SN - 0780393376 KW - cardiac cell KW - tubular system KW - quantitative modelling N2 - Experimental data related to the transverse - axial tubular system of guinea pig and rat ventricular myocytes were incorporated into quantitative models of their electrical activity. The results of simulations suggest that activity-dependent depletion of Ca within the tubular lumen decreases the intracellular Ca-load and intracellular Ca-transients in both species. However, considerable species differences in the magnitude of the depletion, its frequency dependence and the resulting effect on cellular activity were observed. ER -
PÁSEK, Michal, Jiří ŠIMURDA, Clive ORCHARD a Georges CHRISTÉ. Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study. In \textit{Computers in cardiology 2005}. Lyon: IEEE, 2005, s.~993-995. ISBN~0-7803-9337-6.
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