TRÁVNÍČEK, Z., Jaromír MAREK and L. SZÜČOVÁ. trans-Bis{2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine-N7}platinum(II) dimethylformamide disolvate. Acta Crystallographica Section E: Structure Reports Online. Chester, UK: IUCr, E62, No 7, p. m1482-m1484, 3 pp. ISSN 1600-5368. 2006.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name trans-Bis{2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine-N7}platinum(II) dimethylformamide disolvate
Name in Czech trans-Bis{2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine-N7}platnatý komplex s dvěma solvátovými molekulami dimethylformamidu
Authors TRÁVNÍČEK, Z. (203 Czech Republic), Jaromír MAREK (203 Czech Republic, guarantor) and L. SZÜČOVÁ (203 Czech Republic).
Edition Acta Crystallographica Section E: Structure Reports Online, Chester, UK, IUCr, 2006, 1600-5368.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10402 Inorganic and nuclear chemistry
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.567
RIV identification code RIV/00216224:14310/06:00016905
Organization unit Faculty of Science
UT WoS 000238731900020
Keywords in English cyclin-dependent kinase; CDK inhibitor; anti-cancer; transition metal complex; platinum complex
Tags anti-cancer, CDK inhibitor, cyclin-dependent kinase, platinum complex, transition metal complex
Tags Reviewed
Changed by Changed by: doc. RNDr. Jaromír Marek, Ph.D., učo 1989. Changed: 12/12/2006 10:04.
Abstract
The title complex, trans-[PtIICl2(C15H16ClN5O)2].2C3H7NO, is centrosymmetric, with square-planar coordination of the Pt atom within a trans-Cl2N2 donor set. The complex is connected through O-H...O hydrogen bonds to two dimethylformamide solvent molecules. The complex is the first structural example of a Pt(II) complex involving two coordinated cyclin-dependent kinase inhibitors, viz. 2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine.
Abstract (in Czech)
Titulní komplex, trans-[PtIICl2(C15H16ClN5O)2].2C3H7NO, je centrosymetrický se čtvercově-planární koordinací centrálního Pt atomu a trans-konfigurací Cl2 N2 ligandů. Komplex je O-H...O vodíkovými vazbami spojen se dvěma solvátovými molekulami dimethylformamidu. Jde o první popsanou strukturu Pt(II) komplexu obsahující 2 koordinované inhibitory cyklin dependentní kinázy, CDK (konkrétně 2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurin).
Links
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
PrintDisplayed: 17/4/2024 05:20