Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques

HUDEČEK, Robert, Pavel VENTRUBA, Constantinos TSOMPSOS, Eva RAČANSKÁ, Radka VAVRUŠOVÁ a Karel NOVÁK. Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques. Helen. Jour. Obstet. Gynecol. Řecko: Helen. Jour. Obstet. Gynecol, 2006, roč. 5/2006, č. 5, s. 75-79, 4 s. ISSN 1109-4117.

Základní údaje

• Originální název: Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
• Název česky: Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
• Název anglicky: Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
• Autoři: HUDEČEK, Robert, Pavel VENTRUBA, Constantinos TSOMPSOS, Eva RAČANSKÁ, Radka VAVRUŠOVÁ a Karel NOVÁK.
• Vydání: Helen. Jour. Obstet. Gynecol, Řecko, Helen. Jour. Obstet. Gynecol, 2006, 1109-4117.

Další údaje

• Originální jazyk: řečtina stará
• Typ výsledku: Článek v odborném periodiku
• Obor: 30214 Obstetrics and gynaecology
• Stát vydavatele: Řecko
• Utajení: není předmětem státního či obchodního tajemství
• Organizační jednotka: Lékařská fakulta
• Klíčová slova anglicky: Malignancy occurance; infertility; assisted reproduction techniques
• Štítky: assisted reproduction techniques, infertility, Malignancy occurance
• Příznaky: Mezinárodní význam, Recenzováno

Anotace

The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).

Anotace česky

The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).

Anotace anglicky

The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).

Návaznosti

• NO7696, projekt VaV: Název: Ovariální karcinom a léčba neplodnosti metodami in vitro fertilizace - analýza rizikových faktorů pomocí systému pro dolování znalostí z databází SHLUK a umělé neuronové sítě NEUL 3