BIENERTOVÁ VAŠKŮ, Julie, Vladimír VAŠKŮ, Petr BIENERT and Anna VAŠKŮ. Polymorphisms in Energy Homeostasis Genes are Associated with Cutaneous T-Cell Lymphoma (Polymorphims in Energy Homeostasis Genes are Associated with Cutaneous T-Cell Lymphoma). In Tumor Markers Research Perspectives. New York: Nova Publishers, 2007, p. 5-15, 10 pp. XX - in press. ISBN 1-60021-423-1.
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Basic information
Original name Polymorphisms in Energy Homeostasis Genes are Associated with Cutaneous T-Cell Lymphoma
Name in Czech Polymorfismy v genech kontrolujících energetickou homeostázu u pacientů s kožními T-lymfomy
Authors BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor), Vladimír VAŠKŮ (203 Czech Republic), Petr BIENERT (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic).
Edition New York, Tumor Markers Research Perspectives, p. 5-15, 10 pp. XX - in press, 2007.
Publisher Nova Publishers
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30216 Dermatology and venereal diseases
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/07:00021739
Organization unit Faculty of Medicine
ISBN 1-60021-423-1
Keywords in English gene; cutaneous T-cell lymphoma; adipokines; leptin; adiponectin
Tags adipokines, adiponectin, cutaneous T-cell lymphoma, gene, leptin
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Julie Dobrovolná, Ph.D., učo 4805. Changed: 1/7/2008 09:51.
Abstract
In conclusion, this study suggests that genetic variation in the adiponectin and proopiomelanocortin genes may act as attractive susceptibility markers for cutaneous T-cell lymphoma (CTCL). In contrast, no association of variability in tandem region of leptin gene with CTCL has been observed. The role of the adiponectin as well as POMC as genetic markers of CTCL will require further investigation to elucidate the underlying pathophysiological consequences.
Abstract (in Czech)
Naše výsledky naznačují, že polymorfní oblasti v genech kontrolujících energetické hospodaření organismu (leptin, adiponektin, proopiomelanokortin) se uplatňují jako atraktivní genetické markery rizika pro kožní T-lymfom.
Links
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
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