2007
The role of major histocompatibility complex diversity in vigour of fish males (Abramis brama L.) and parasite selection
OTTOVÁ, Eva, Andrea ŠIMKOVÁ a Serge MORANDZákladní údaje
Originální název
The role of major histocompatibility complex diversity in vigour of fish males (Abramis brama L.) and parasite selection
Název česky
Úloha hlavního histokompatibilitního komplexu ve vztahu k vitalite samců cejna velkeho (Abramis brama L.) a parazitické selekci
Autoři
OTTOVÁ, Eva (203 Česká republika), Andrea ŠIMKOVÁ (203 Česká republika, garant, domácí) a Serge MORAND (250 Francie)
Vydání
Biological Journal of the Linnean Society, Blackwell Publishing, 2007, 0024-4066
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
10600 1.6 Biological sciences
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 2.368
Kód RIV
RIV/00216224:14310/07:00020123
Organizační jednotka
Přírodovědecká fakulta
UT WoS
000245107100012
Klíčová slova anglicky
DAB genes MHC polymorphism parasite-driven selection sexual ornamentation
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 31. 3. 2011 12:48, prof. RNDr. Andrea Vetešníková Šimková, PhD.
V originále
The MHC presents a group of genes with highly polymorphic loci involved in specific immune response. The factors maintaining extensive MHC polymorphism have been questioned considering three possible hypotheses of parasite-mediated selection driving an extensive MHC diversity, i.e. heterozygote advantage, rare-allele advantage and favouring optimal MHC diversity. The patterns of MHC diversity of class IIB genes were investigated following two non-contradicting hypotheses: parasite-driven selection and MHC-based mating preferences, using males of common bream collected in the spawning period. Two allelic groups DAB1 and DAB3 were recognized from the phylogenetic analyses. Individuals expressed one or two alleles of the same or different allelic groups. Several individuals shared identical alleles, however, the presence of parasite species was not associated with the occurrence of a particular allele. The presence of different allelic groups (only DAB1, only DAB3 or both DAB1 and DAB3) in individuals was not associated with parasite presence or diversity. The expression of two DAB1 alleles was associated with higher endoparasite abundance. Moreover, nucleotide diversity in individuals expressing a single type of alleles (DAB1 or DAB3) increased with the abundance of ectoparasitic Dactylogyrus spp. (Monogenea) and Ergasilus sp. (Crustacea). This suggests that the expression of two alleles of a single allelic type is connected with high metazoan parasite infection whilst no significant influence of parasitism on the combined allelic form (the presence of both DAB1 and DAB3 alleles) was found. Moreover, the expression of two alleles of a single allelic type was connected with decreased immunocompetence measured by spleen size. The condition factor was higher in fish expressing the combined allelic type. Thus, the presence of alleles of different lineages in individuals seems to be advantageous for individual male fitness. The expression of a single allelic type was connected with higher sexual ornamentation, which could support the role of MHC in connection with hypothesis of sexual selection of good genes.
Česky
The MHC presents a group of genes with highly polymorphic loci involved in specific immune response. The factors maintaining extensive MHC polymorphism have been questioned considering three possible hypotheses of parasite-mediated selection driving an extensive MHC diversity, i.e. heterozygote advantage, rare-allele advantage and favouring optimal MHC diversity. The patterns of MHC diversity of class IIB genes were investigated following two non-contradicting hypotheses: parasite-driven selection and MHC-based mating preferences, using males of common bream collected in the spawning period. Two allelic groups DAB1 and DAB3 were recognized from the phylogenetic analyses. Individuals expressed one or two alleles of the same or different allelic groups. Several individuals shared identical alleles, however, the presence of parasite species was not associated with the occurrence of a particular allele. The presence of different allelic groups (only DAB1, only DAB3 or both DAB1 and DAB3) in individuals was not associated with parasite presence or diversity. The expression of two DAB1 alleles was associated with higher endoparasite abundance. Moreover, nucleotide diversity in individuals expressing a single type of alleles (DAB1 or DAB3) increased with the abundance of ectoparasitic Dactylogyrus spp. (Monogenea) and Ergasilus sp. (Crustacea). This suggests that the expression of two alleles of a single allelic type is connected with high metazoan parasite infection whilst no significant influence of parasitism on the combined allelic form (the presence of both DAB1 and DAB3 alleles) was found. Moreover, the expression of two alleles of a single allelic type was connected with decreased immunocompetence measured by spleen size. The condition factor was higher in fish expressing the combined allelic type. Thus, the presence of alleles of different lineages in individuals seems to be advantageous for individual male fitness. The expression of a single allelic type was connected with higher sexual ornamentation, which could support the role of MHC in connection with hypothesis of sexual selection of good genes.
Návaznosti
| GA524/04/1128, projekt VaV |
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| MSM0021622416, záměr |
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