Neopterin and oxidative stress in patients with heart failure

D 2007

Neopterin and oxidative stress in patients with heart failure

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ et. al.

Základní údaje

Originální název

Neopterin and oxidative stress in patients with heart failure

Název česky

Neopterin a oxidační stres u pacientů se srdečním selháním

Autoři

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ a Jindřich ŠPINAR

Vydání

1. vyd. Bratislava, Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention. od s. 97-97, 1 s. 2007

Nakladatel

Mind and Helth, civil association

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Slovensko

Utajení

není předmětem státního či obchodního tajemství

Organizační jednotka

Lékařská fakulta

ISBN

978-80-969663-2-5

Klíčová slova anglicky

heart failure; oxidative stress; neopterin; cell-mediated immunity

Štítky

cell-mediated immunity, Heart failure, neopterin, oxidative stress

Příznaky

Mezinárodní význam

Změněno: 3. 4. 2007 15:44, doc. RNDr. Josef Tomandl, Ph.D.

Anotace

ORIG CZ

V originále

Recent data suggest among others that inflammation and oxidative stress may be associated with the development of heart failure. Neopterin is a sensitive marker for disease involving activated cell-mediated immune system in humans and besides induce oxidative stress in vitro. The aim of our study was to determine neopterin levels in patients with acute myocardial infarction (AMI) and chronic heart failure (CHF) and find a possible relationship with parameters of oxidative stress. The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.

Česky

The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.

Návaznosti

MSM0021622402, záměr

Název: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob

Citovat

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ a Jindřich ŠPINAR. Neopterin and oxidative stress in patients with heart failure. In Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention. 1. vyd. Bratislava: Mind and Helth, civil association, 2007, s. 97-97. ISBN 978-80-969663-2-5.

@inproceedings{716014,
   author = {Tomandl, Josef and Pařenica, Jiří and Táborská, Eva and Špinarová, Lenka and Čermáková, Zdeňka and Špinar, Jindřich},
   address = {Bratislava},
   booktitle = {Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.},
   edition = {1.},
   keywords = {heart failure; oxidative stress; neopterin; cell-mediated immunity},
   language = {eng},
   location = {Bratislava},
   isbn = {978-80-969663-2-5},
   pages = {97-97},
   publisher = {Mind and Helth, civil association},
   title = {Neopterin and oxidative stress in patients with heart failure},
   year = {2007}
}

TY  - JOUR
ID  - 716014
AU  - Tomandl, Josef - Pařenica, Jiří - Táborská, Eva - Špinarová, Lenka - Čermáková, Zdeňka - Špinar, Jindřich
PY  - 2007
TI  - Neopterin and oxidative stress in patients with heart failure
PB  - Mind and Helth, civil association
CY  - Bratislava
SN  - 9788096966325
KW  - heart failure
KW  - oxidative stress
KW  - neopterin
KW  - cell-mediated immunity
N2  - Recent data suggest among others that inflammation and oxidative stress may be associated with the development of heart failure. Neopterin is a sensitive marker for disease involving activated cell-mediated immune system in humans and besides induce oxidative stress in vitro. The aim of our study was to determine neopterin levels in patients with acute myocardial infarction (AMI) and chronic heart failure (CHF) and find a possible relationship with parameters of oxidative stress. The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.
ER  -

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ a Jindřich ŠPINAR. Neopterin and oxidative stress in patients with heart failure. In \textit{Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.}. 1. vyd. Bratislava: Mind and Helth, civil association, 2007, s.~97-97. ISBN~978-80-969663-2-5.

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