| STROUHAL, Michal, Petra MATĚJKOVÁ, David ŠMAJS, E. SODERGREN, S. J. NORRIS a G. M. WEINSTOCK. Comparative genomics of closely related treponemal strains. In In Abstract Book: 17th European Congress of Clinical Microbiology and Infectous Diseases, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. Munich, Germany: European Congress of Clinical Microbiology and Infectous Diseases, 2007, s. 915. ISSN 0924-8579. |
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@inproceedings{720020,
author = {Strouhal, Michal and Matějková, Petra and Šmajs, David and Sodergren, E. and Norris, S. J. and Weinstock, G. M.},
address = {Munich, Germany},
booktitle = {In Abstract Book: 17th European Congress of Clinical Microbiology and Infectous Diseases, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS},
keywords = {Comparative genomics; treponemal strains},
language = {eng},
location = {Munich, Germany},
pages = {915-915},
publisher = {European Congress of Clinical Microbiology and Infectous Diseases},
title = {Comparative genomics of closely related treponemal strains},
year = {2007}
}
TY - JOUR
ID - 720020
AU - Strouhal, Michal - Matějková, Petra - Šmajs, David - Sodergren, E. - Norris, S. J. - Weinstock, G. M.
PY - 2007
TI - Comparative genomics of closely related treponemal strains
PB - European Congress of Clinical Microbiology and Infectous Diseases
CY - Munich, Germany
KW - Comparative genomics
KW - treponemal strains
N2 - Genus Treponema includes several pathogenic spirochetes: Treponema pallidum ssp. pallidum (TPA) is the causative agent of sexually transmitted syphilis, Treponema pallidum ssp. pertenue (TPE) causes endemic nonveneral treponemal infections and T. paraluiscuniculi (TPAR) is the etiologic agent of veneral syphilis in rabbits and does not infect humans. These treponemes cannot be continuously cultivated under in vitro conditions and are indistinguishable by morphological and serological methods. In this study, genomes of closely related treponemes were compared. When compared to the Nichols genome the prominent indels and sequence changes were preferentially localised in tpr genes (and in the hypothetical genes in the vicinity of tpr genes). Differences in number of tandem repetitions within the gene TP470 and genes TP0433-4 (hypothetical genes) were detected in all analysed strains. In the second case fusion of both genes (TP0433-4) resulted in one acidic repeat protein gene (arp gene).
ER -
STROUHAL, Michal, Petra MATĚJKOVÁ, David ŠMAJS, E. SODERGREN, S. J. NORRIS a G. M. WEINSTOCK. Comparative genomics of closely related treponemal strains. In \textit{In Abstract Book: 17th European Congress of Clinical Microbiology and Infectous Diseases, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS}. Munich, Germany: European Congress of Clinical Microbiology and Infectous Diseases, 2007, s.~915. ISSN~0924-8579.
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