LANDA, Leoš and Michal JURAJDA. Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain. European Neuropsychopharmacology. Amsterdam: Elsevier, 2007, vol. 17, Suppl. 4, p. S557-S557, 1 pp. ISSN 0924-977X.
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Basic information
Original name Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain
Name in Czech Akutní a opakovaná expozice metamfetaminu mění expresi CB1 receptoru v mesencefalonu myšího mozku
Authors LANDA, Leoš and Michal JURAJDA.
Edition European Neuropsychopharmacology, Amsterdam, Elsevier, 2007, 0924-977X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Austria
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 4.430
Organization unit Faculty of Medicine
UT WoS 000251231901273
Keywords in English PCR; behavioural sensitization; methamphetamine; cannabinoids; CB1 receptor; mesencephalon
Tags behavioural sensitization, cannabinoids, CB1 receptor, mesencephalon, methamphetamine, PCR
Tags International impact, Reviewed
Changed by Changed by: MUDr. Michal Jurajda, Ph.D., učo 24045. Changed: 19/6/2009 14:20.
Abstract
Real-time PCR results showed increased CB1 mRNA expression after both methamphetamine and methanandamide first doses followed by decrease in CB1 mRNA expression observed after the challenge dose of methamphetamine, i.e. in sensitized animals.
Abstract (in Czech)
Výsledky real time PCR ukázaly zvýšenou expresi mRNA CB1 jak po první dávce metamfetaminu tak metanandamidu a následně snížení exprese mRNA CB1, která bylo pozorováno po provokující dávce metamfetaminu, tzn. u senzitizovaných zvířat.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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